gpcr1949

6 ms·

1.
Grok's Profile Fills with AI Bikini Edits Sparking Consent Backlash(x.com)
17 points by gpcr1949 9mo ago|0 comments
2.
by gpcr1949 1y ago
I think it is an underestimation to say ~800 people died in the Gaza war. The Ukraine number also seems like a serious underestimation.
3.
New Mersenne Prime discovered (probably)(mersenne.org)
2 points by gpcr1949 2y ago|1 comments
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by gpcr1949 2y ago
Israel is committing what some experts are calling a genocide. In any case, they killed a lot of civilians. It can probably be debated whether this is noble or "striving to be better". But either way, the political beliefs and hob
5.
Meta 'pauses' AI data collection in EU following Irish DPC request(independent.ie)
4 points by gpcr1949 2y ago|0 comments
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by gpcr1949 3y ago
I am really surprised they fired him for a really relatively mild series of tweets. I know some of the Israeli scientists leading the campaign against him also pointed out he tweeted "Fuck Israel" in 2018 [0]. Due to the date, May
7.
by gpcr1949 3y ago
Writing Basel as Bâle would be silly and non-standard too, yes. Maybe "wrong" is too strong of a classification. But for example, I wouldn't immediately recognize it as Basel in a headline. FWIW Leuven refers to itself in En
8.
by gpcr1949 3y ago
Interesting history, but people in Leuven call this city Leuven and not Louvain. No need to use the french term in a flemish city where almost no one speaks french as their first language. In fact, french language was the subject of some am
9.
by gpcr1949 3y ago
https://archive.vn/lByGj
10.
The rise of the new tech right(newstatesman.com)
2 points by gpcr1949 3y ago|1 comments
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by gpcr1949 3y ago
They use a random forest classifier, which is an ensemble model that gives a consensus result of several decision trees. One way to achieve this consensus is voting. Random forest models are commonly used in building chemical models like th
12.
by gpcr1949 4y ago
High-throughput screening (HTS), i.e. testing a large amount of compounds in simple biochemical assays can't be compared with testing 10 compounds in monkeys. The point of HTS is finding active substances in a large collection of compo
13.
by gpcr1949 4y ago
You can read about the development of this new route and its advantages here [0]. Ctrl+F for ibuprofen or go to p.54. https://sci-hub.se/10.1016/B978-0-12-804190-1.00004-5
14.
by gpcr1949 4y ago
Agreed the process is very simple. The innovation that makes the resolution worth it is (as Derek also mentioned in the blog post) an efficient way to re-racemize the L-meth to DL-meth, which can then be resolved again. With steady state pr
15.
by gpcr1949 4y ago
This is really a scandalously misinformed stunt. The chemical they released is SO_2 - one of the gasses and car pollutants causing acid rain.
16.
by gpcr1949 4y ago
I was wondering the same thing. I found this in a guardian article > The military’s firefighters use aqueous film-forming foam, or AFFF, which contains extremely high levels of PFAS, in training exercises and emergencies. Though AFFF is
17.
by gpcr1949 4y ago
Good to see the results respect Benford's law and are therefore not fabricated.
18.
by gpcr1949 4y ago
I may be misreading it, but doesn't the GoL as commonly understood also depend on diagonal neighbors (i.e. 8 direct neighbors)? In that case the rule space would explode beyond the 32 bit integer one. (to a 256 bit one)
19.
by gpcr1949 4y ago
BOL-148 is not like the others. All others are N1-acyl analogs of LSD, so unlike bol148 they rapidly metabolize to LSD proper. This also means until they make a prodrug or analog law, it will be easy to keep on thinking of new LSD prodrugs.
20.
by gpcr1949 4y ago
They definitely will, this is after all the intended purpose of these firms, and some of the more professional among them are producing cGMP APIs at scale in a completely legitimate context. Although if you have a need for ACE2 inhibitors (
21.
by gpcr1949 4y ago
Fluorine on an aromatic ring is not labile: other examples of substances with fluorinated aromatic rings are fluoxetine(prozac), citalopram (celexa) and paroxetine (paxil), which are antidepressants many people are taking daily without fluo
22.
by gpcr1949 4y ago
With all due respect for the forensic chemists and their good work on identifying an unknown substance, it is fairly common for forensic groups to once in a while detect new chemical analogs of known drugs. A few years back, lots of new can
23.
by gpcr1949 4y ago
Pretty unlikely. The F would be already in place at an early stage, the precursor is probably 2-F-benzonitrile, alternatively 2-f-phenylmagnesium bromide.
24.
Every Class Is Some Student's Orgo(chadorzel.substack.com)
2 points by gpcr1949 4y ago|0 comments
25.
by gpcr1949 4y ago
(I have a background in organic chemistry as well) I somewhat disagree with this. Measuring chemical similarity is notoriously difficult, see these two interesting blog posts from a cheminformatic angle [0][1]. The molecules are not only ph
26.
by gpcr1949 4y ago
Of course, it's somewhat disappointing that any molecule you look at will result in isomerization of cis-retinal to trans-retinal - including a picture of the consumed cis-retinal. Another interesting example where molecules will produ
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by gpcr1949 4y ago
Exploring the neighborhood around what I like usually works. This means: see what's released on the same music labels. See which journalists and bloggers wrote about the thing i liked. See what artists the original artist considers to
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by gpcr1949 4y ago
a quick and dirty trick to have a limiter on the signal is put [tanh~] between your signal and the dac
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by gpcr1949 4y ago
> Sorry, that email domain is not recognized. -- An email address from a recognized U.S. school or university is required. If your school's domain is not recognized, please request it to be allowed by clicking HERE edit: to add some
30.
by gpcr1949 4y ago
The nitrogen source is effectively in the nutrients (so not air/nitrogen fixation by their organism), and is provided as ammonia, according to this video by Solar Foods[0]. I agree this is cheating considering what is needed to produce

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