5 ms·
With all due respect for the forensic chemists and their good work on identifying an unknown substance, it is fairly common for forensic groups to once in a whi
by gpcr1949 4y ago
With all due respect for the forensic chemists and their good work on identifying an unknown substance, it is fairly common for forensic groups to once in a while detect new chemical analogs of known drugs. A few years back, lots of new cannabinoids and cathinones were getting released constantly as older analogs were getting banned. Often, these novel analogs are pharmacological low hanging fruit. The drug in this article is also such low-hanging fruit: it is well known an N-methyl to N-ethyl substitution does not lead to reduced activity in this category of arylcyclohexylamine dissociative anesthetics (this was actually one of the SAR considerations taken by the designers of methoxetamine!). And indeed, this very same substitution was used here on 2-Fluorodeschloroketamine, leading to the drug from the article.
PS the Chinese abbreviation for "CanKet", 2F-NENDCK, most likely stands for 2-fluoro-N-ethyl-nordeschloroketamine. It is almost certain this drug was synthesized by a Chinese custom synthesis group (the most typical source for these type of substances at scale) and not by Australian clandestine chemists.
- girvo 4y agoIndeed. Though as a semi-related aside, Canberra recently had some stats put out where quite literally less that 50% of "ketamine" tested was actually ketamine, most of the street ketamine out here now are these research chemical analogs.
- tsol 4y ago>It is almost certain this drug was synthesized by a Chinese custom synthesis group (the most typical source for these type of substances at scale) and not by Australian clandestine chemists. Most people don't realize this, but you can order a synthesis of just about any (legal) chemical with enough money. People do it for pharmaceutical or nootropic drugs sometimes in group buys. It's trivial if you have enough money to find some vaguely legal analog of a recreational drug, and order a synthesis of it. 2f-dck is a ketamine analog that I believe is still legal and reported to be very similar in effect, and I'd guess 2f-nendck is somewhat similar to that. Not that I'm suggesting anyone should, there are risks and it's not an easy process. It's just interesting how easily accessible it is if you have the right information.
- Loic 4y agoTo the point to be annoying. I am running an open database of chemical properties[0], I get nearly every single day Chinese companies proposing me to buy whatever compounds they are producing including non legal ones. Even more stupid, I get phone calls and email asking me if I can source stupidly well known illegal drug for a friend doing some research. Even if this is clear that I am just providing experimental data and no chemicals at all. So yes, you can get chemicals very easily and you have a lot of providers which are not really looking at the legality of the stuff. [0]: https://www.chemeo.com https://www.chemeo.com
- rendall 4y agoA friend is looking to do research into any one of the following: Can-D, Chew-Z, skooma (moon sugar ok), Jet or UltraJet, spark, spike, spin or spank, and velocet. They are prepared to pay well. You can reach them here: https://youtu.be/PZqx-lMZHM0 https://youtu.be/PZqx-lMZHM0
- Our_Benefactors 4y agoSorry, only Zyme is available these days.
- zasdffaa 4y agoHowzabout some clarky cat? https://www.youtube.com/watch?v=MIAJemmO-bg https://www.youtube.com/watch?v=MIAJemmO-bg The first 5 minute of this is one of the funniest things I've watched.
- rendall 4y agoThis video contains content from LDS, who has blocked it in your country on copyright grounds Weird. Mormons getting salty?
- zasdffaa 4y agoThat's a pity. It's from Brass Eye (https://en.wikipedia.org/wiki/Brass_Eye https://en.wikipedia.org/wiki/Brass_Eye), a piss-take on panicky documentaries, it's the drugs one and totally brilliant. And they got a mandrill on it. Most of them are well worth a watch, get them if you can.