soudiere

9 ms·

1.
by soudiere 3y ago
Many reasons, that's a different discussion. Note that you've gone from this statement, to acknowledging that they are regularly prescribed. > Imagining a doctor writing a script for meth is pretty amusing, and maybe if that’s
2.
by soudiere 3y ago
That statement is true of all amphetamines. Look, this is what I'm driving at, you appear to have some illusions that methamphetamine is significantly different than other amphetamines, or has some higher toxicity profile, more addicti
3.
by soudiere 3y ago
Not playing obtuse, trying to get you to say why you think it's so crazy. Section 3 of this 2019 paper has stats on meth (desoxyn) prescriptions https://www.medrxiv.org/content/10.1101/2022.05.23.22275471v...
4.
by soudiere 3y ago
You most likely did far more than 50mg of methamphetamine. I just weighed a couple 20mg orange adderall pills, they're each around 0.2-0.3 grams (my scale is only accurate to 0.1g)
5.
by soudiere 3y ago
That is not what racemic means, ratios can exist. There's a whole section, "Single-Isomer Versus Racemic Formulation", in this recent review article titled "Novel Formulations of ADHD Medications: Stimulant Selection and
6.
by soudiere 3y ago
Why is it amusing? Because you think it has no therapeutic value?
7.
by soudiere 3y ago
Serotonegic? What does that even mean? For a given quantity, eg 1mg, of methylamphetamine vs d-amphetamine, the meth will release more serotonin?
8.
by soudiere 3y ago
The worst discussions we have on Hacker News are around healthcare and medicine. For some reason the community refuses to apply a high of research and rigor to this topic, as if it's lesser than the non-sense we call computer science.
9.
by soudiere 3y ago
DEA isn't the issue here. The Justice Department brought the lawsuit against Purdue Pharma, and distributors are scared.
10.
by soudiere 3y ago
Higher potency, longer duration of action. If your goal was to get inebriated (drinking), would everclear be more effective than vodka?
11.
by soudiere 3y ago
Why does it blow your mind?
12.
by soudiere 3y ago
People who do a lot of meth tend to smoke it. Method of administration affects the time delay for euphoria. Smoke > Shooting > Eating. People who do a lot of meth (or drugs outside of a prescription) tend to do as much as they can pur
13.
by soudiere 3y ago
Bingo
14.
by soudiere 3y ago
Yeah, this guy doesn't know what he's talking about. If we just discussed this as d-amphetamine, l-amphetamine & methyl-amphetamine, the issue of interchangeability would be less confusing.
15.
by soudiere 3y ago
Adderally XR formulations are still a minority of prescriptions. Talking about methamphetamine as a different molecule is not helpful, as Adderall itself is not a single molecule. Which I suspect you know, as you mention different enantiome
16.
by soudiere 3y ago
I've tried both as well, and I suspect your lying to yourself about potency. I certainly didn't have a scale to measure the dosage to match say a 10mg orange adderall pill. By analogy, if you did a 75ml "shot" of alcohol
17.
by soudiere 3y ago
Nah fam, this is fallout from Purdue pharma litigation, distributors are figuring out how to shield their future liability. Have a read here from people who work in the industry https://www.reddit.com/r/medicine/co
18.
by soudiere 3y ago
> The reason for the remaining C-Section was that she "needed" a C-Section before. Yeah she probably had a vertical incision c-section, which clinically indicates a c-section for the next birth. You can read about it, the fiber
19.
by soudiere 3y ago
I said read the guidelines. Casually scanning the literature on pubmed shows babies that come out after IDK 39 weeks have sometimes not great outcomes, and it gets worse as time goes on. You say "the baby will come out when they'r
20.
by soudiere 3y ago
A little over 800 per 100,000 in 1900 per CDC data. Infant mortality was 10% in 1915. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm4838a2.htm
21.
by soudiere 3y ago
Dude, what common sense approaches about pregnancy do you think go against the scientific recommendations? Please take a look at the CDC data over the last century. In 1915 infant mortality was _10_ percent. Maternal mortality was around 0.
22.
by soudiere 3y ago
Of course he hasn't. Imagine talking to this guy in the delivery room. "Evolution has selected for safe child birth, nuchal cord isn't a problem". At that point every professional in the room is thinking "How do we
23.
by soudiere 3y ago
I'm certainly an asshole, and drunk, but at least I can read and look up studies on pubmed. What are you even arguing about nuchal cords? They're common and we should ignore them? Who cares that the "complications" are f
24.
by soudiere 3y ago
Sure, patient (mother) gets to make decisions about what treatments they want, clinician advises them on the pros/cons of each option. Just pointing out squat birthing isn't the panacea some people paint it as. The study wasn&#x27
25.
by soudiere 3y ago
Rate of complications will be the same, outcomes from those complications won't be the same. Accident rates on the highway might be say, equal among people who do/don't wear seatbelts, but outcomes are not. Look at common com
26.
by soudiere 3y ago
Humor me, what did science actually get wrong in this article? The milk transfusions were shitty solution for lack of blood during a cholera epidemic, but the articles claims are false "In the late 19th century, milk was believed to be
27.
by soudiere 3y ago
Same, I linked him a paper on the error margin of these scans in another comment. The poor assumption here is the error margin at 18-19 weeks is the same at 36 weeks. Might be worth reviewing the ACOG's recommendations on post-term del
28.
by soudiere 3y ago
Imagine working with this guy on a software system. Says no to established best practices across the board "no" to version control, CI/CD, vulnerability scans, patching and all the interventions. Gets one project off the grou
29.
by soudiere 3y ago
Squat birthing is a nice idea, but you have to look at the evidence, it's good for some things and maybe not great for other things like cesarean (RR 2.26 in this meta analysis) https://www.sciencedirect.com/science&#x2
30.
by soudiere 3y ago
Inventors were a wife/husband pair...

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