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naveenspark
searching Neon…
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by
naveenspark
8y ago
Founders should invest time and effort to ask for more board seats. The YC doc is a good start but if you follow this to the letter you may lose control in your B or C when the B and C investor also want board seats. Also it’s important to
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naveenspark
8y ago
You could always try the startup for 1 year and see how it goes. This way you get past your cliff, and you will have a much better idea of whether or not it has a chance of becoming something. If its flopping around like a fish then you can
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naveenspark
10y ago
Its unclear what Peter Thiel is supporting with this donation. This candidate is highly inconsistent. Perhaps his bet is that if this candidate is elected, it will result in chaos. A sharp, rapid upheaval will enable him to accelerate hi
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naveenspark
10y ago
Great point. Editing my post to include this.
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naveenspark
10y ago
Offering to cover defense increases their overall cost. If they agree to provide defense up front prior to anyone filing, and they are able to file first, they are able to make the bet that the opposing party won't file a counter. If
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naveenspark
10y ago
From personal experience, the moment someone does any work on a project they have a claim. The state of CA is extremely worker friendly in this regard. I've made this stupid mistake twice in two different startups unrelated to Immu
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naveenspark
11y ago
David and Chris are extraordinary entrepreneurs. I learned a lot watching them build Zesty week over week during YC W14. This is a hard business to build. Providing consistent service in terms of restaurant relations, food quality, and d
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naveenspark
11y ago
Taylor Swift is signed to Big Machine Records (BMLG). Big Machine Records is distributed by Universal Music Group (UMG). I am sure BMLG/UMG received a sizable advance from Apple in exchange for streaming rights for their master recor
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Keys: Musical Keyboard with Gesture Controls, Modularity, and LEDs
(playkeys.io)
30 points
by
naveenspark
12y ago
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18 comments
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naveenspark
12y ago
Thank you! Our article is open access on ScienceDirect here: http://bit.ly/SKzPgO
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Immunity Project gets published in Vaccine
(immunityproject.org)
44 points
by
naveenspark
12y ago
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5 comments
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naveenspark
12y ago
I live and work in Oakland. My office is 3 blocks from 19th street BART in the heart of uptown. There is so much incredible development happening in this part of the city. The Hive project launches later this year (The Hub is already ope
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naveenspark
12y ago
The base compensation is reasonable given the high cost of living in SF and the personal risk associated with the job. The pension is tougher to justify. Up to 90% of your salary at age 58 until EOL is likely unsustainable for the city.
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naveenspark
12y ago
Not sure why this is ruffling so many feathers. There are thousands of great tech companys to work for that aren't on any Google, Apple or EBay "no-hire" list and vice versa. I fail to see how a few big companys agreeing no
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naveenspark
12y ago
Disclosure: I am biased (Noora is in our YC batch). That being said, what Noora is doing is very important. If patients and caregivers have better education on what to do post treatment, outcomes improve. The cost savings gained from th
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naveenspark
13y ago
Apologies if my post felt unnecessarily snarky. Yes I am cofounder @ Immunity Project, but I previously helped create Redbox Tickets so I have that hat on for this thread. My opinion on the video aside, when you have a line of people in f
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naveenspark
13y ago
This feels gimmicky. How does this help solve real issues with admission control? The idea of admitting based on a face vs. a barcode for a reserved show won't work. Assuming this is for GA only? Why not just allow users to import
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naveenspark
13y ago
Congrats Sam! Thank you for the ridiculously good advice you give us and our fellow YC founders. The future is very bright for YC.
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naveenspark
13y ago
Hey this is Naveen from Immunity Project. We had a great experience w/ Crowdhoster. It performed well for us and Ajay + team were super responsive. Highly recommend it for those who are considering crowdfunding on their own domain.
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naveenspark
13y ago
We are using TrueVault for Immunity Project. We have some bias since TrueVault is in our YC batch, but Jason and Trey worked 24/7 to help us with our HIPAA compliance needs. They used their API to build a custom portal for us to secu
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naveenspark
13y ago
Thank you for the kind words and support! We are very focused on our stated goal which is ending HIV/AIDS with a free vaccine. We haven't received any pressure to stop our work yet. If we do we will definitely let you know so w
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naveenspark
13y ago
Naveen here from Immunity Project. Thanks for the question. We have not done receptor analysis. We are using animal models as our starting point - we are looking for an immune response with memory to the administered peptides - if we get
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naveenspark
13y ago
The article is describing one of the many explanations that has been brought forward to explain why controllers do what they do. If you are looking for a common denominator across controllers broadly, the selective epitope targeting explan
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naveenspark
13y ago
More then happy to give you the full details on how we've set this up: the vaccine is being developed by Flow Pharma Inc. Instead of setting up our own 501(c)3, we setup a fiscal sponsorship agreement with Until There's A Cure,
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naveenspark
13y ago
Right now the project is only relying epitopes derived from actual controller targets. Our hypothesis is that if we go after the epitopes that HIV controllers preferentially target that we will get an immune response with memory in humans
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naveenspark
13y ago
Thank you for your support!
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naveenspark
13y ago
Yes our overhead is far lower. Our other "trick" is that several members of our team are multi-talented. For example Dr. Herst can do tissue culture work, formulation development, analytical chemistry, and immunochemistry.
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naveenspark
13y ago
HIV/AIDS is a giant problem. North of 35MM people are living with HIV worldwide and more are infected every day. Yes we have made strides in reducing infection rates, but we are far from solving this problem with existing approaches.
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naveenspark
13y ago
Thank you for your support! Yes it will be presented as a double blind, placebo controlled study. Regarding the risky behavior point, this is a well known challenge with all vaccine studies. And yes telling people that they don't kn
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naveenspark
13y ago
We are pursuing all major funders we know of for funding for our work (including Bill and Melinda Gates Foundation etc.). The challenge is that it takes significant time to prepare grants apps, and go through the process. Some large funde
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