5 ms·
Naveen here from Immunity Project. Thanks for the question. We have not done receptor analysis. We are using animal models as our starting point - we are look
by naveenspark 13y ago
Naveen here from Immunity Project. Thanks for the question. We have not done receptor analysis. We are using animal models as our starting point - we are looking for an immune response with memory to the administered peptides - if we get that response in Phase I we should be in good shape!
We received the peptides from researchers who have a manuscript in publication and would like us to keep the sequences confidential until they publish. Please see below for similar statistical research looking for targets to beneficial regions on HIV:
Mothe B, Anuska L, Ibarrondo J, Daniels M, Miranda C, Zamarreno J, et al. Definition of the viral targets of protective HIV-1-specific T cell responses. Journal of Translational Medicine 2011;9(208):20.
re: your startup / cost savings on reagents, supplies and equipment, we would love to talk to you about that. Please email us at team@immunityproject.org. Thanks!