dpatrick86

7 ms·

1.
by dpatrick86 7mo ago
It would be really interesting if cars did this by default. Maybe it could figure out your threshold, how much of an outlier you are, and then you could opt-in to a new threshold that's somewhat better and/or closer to average.
2.
by dpatrick86 2y ago
Artificial is fine and playing word games for pedants is a trap.
3.
by dpatrick86 4y ago
Getting big "on a bender" vibes from Elon right now...
4.
by dpatrick86 4y ago
Some use cas9, such as dead cas9 (has endonuclease activity removed), and others do not. Great interview where Dr. George Church talks base editing and CRISPR: https://www.foundmyfitness.com/episodes/george-church
5.
by dpatrick86 4y ago
This is being reported as false https://ew.com/music/jerry-lee-lewis-alive-after-erronerous-...
6.
by dpatrick86 6y ago
At least in the case of the heart, there’s the beginnings of evidence that is suggestive of the fact that the damage is not simply incidental to systemic inflammation. https://medicine.wustl.edu/news/covid-19-can-kill-h
7.
by dpatrick86 6y ago
Your point may be broadly true but subject to important caveats. Cancer is a very heterogeneous disease. There is evidence that _some_ cancers can use, for example, acetoacetate. https://www.sciencedaily.com/releases/20
8.
by dpatrick86 6y ago
Wow, refreshing. To me, the most interesting part here is the incentive. It sounds like they ultimately just wanted to rise to the standard once it was made exhaustively clear. The important part here probably being that, by including peers
9.
by dpatrick86 7y ago
Might be inhibiting sirtuin activity... http://www.jbc.org/content/277/47/45099.short
10.
by dpatrick86 7y ago
What makes you think NMN has been "proven to be safe?" That's a pretty strong standard to conform to. There's virtually no clinical work that's been done at all, for starters. A lot of genuine promising research in
11.
by dpatrick86 7y ago
Taken in light of the existence of the glymphatic system, a robust mechanism of clearance activated by slow wave sleep, what is more likely... misfolded protein accumulation is incidental to the loss of sleep during the course of fatal fami
12.
by dpatrick86 7y ago
Allele misassignment is another rampant issue. https://www.ncbi.nlm.nih.gov/pubmed/18154681?dopt=Abstract
13.
by dpatrick86 7y ago
I appreciate your comment, despite not relating to it very well and it seeming a bit strange to me. I know that might come across a bit odd, but it's refreshing to actually try to understand other viewpoints and to do so inoffensively.
14.
by dpatrick86 7y ago
It sure seems like patterns of cortical activation (or something like that) could be compared to some sort of waking standard to take a very good measured guess at some point.
15.
by dpatrick86 7y ago
That's awfully late in life to be developing a foundation for morality. It seems far more likely to be extremely influenced by early upbringing. More controversially, there may even be a genetic component too. https://www.sc
16.
by dpatrick86 7y ago
Interestingly, the legacy of Biosphere 2 includes the recently emerging fasting and fasting-mimicking science demonstrating some interesting healthspan promoting properties. Dr. Roy Walford of Biosphere 2 helped kick off the caloric restric
17.
by dpatrick86 7y ago
This was based on the SELECT trial data, which means that it could just as easily be measuring the effects of a very large and prolonged dose of 400 IU of alpha-tocopherol as it is omega-3. Greater than 12x RDA. Moreover, it's been man
18.
by dpatrick86 7y ago
What if it's both?
19.
by dpatrick86 8y ago
VSL#3 is one that has a lot of clinical research (search Google Scholar or PubMed). The catch is that the company producing VSL#3 no longer uses the formula that historically was used in the vast array of clinical research conducted. Whethe
20.
by dpatrick86 8y ago
Some research is adopting this pattern too. A great example is Dr. Satchin Panda's clinical trial on time-restricted eating. You self-select an eating window and then document it through the app. Pretty cool stuff. mycircadianclock.org
21.
by dpatrick86 8y ago
Not required for the optional smart key system.
22.
by dpatrick86 8y ago
It might be written better as, "Cardiometabolic resilience may be neurobiological." Of course, mental resilience being neurobiological would be a banality, however, they are talking about the strength of a specific brain network b
23.
by dpatrick86 8y ago
Following the instructions pedantically (e.g. emphasizing "uniquely identify," especially for the individuals) probably leads to an enormous biasing of the score.
24.
by dpatrick86 8y ago
Interesting journalistic experiment, however, ads like these are irrelevant unless they can push the amount of exposure that shifts elections. That's going to take a lot of money. The question, then, becomes not whether they can get ad
25.
by dpatrick86 8y ago
On the contrary, Bredesen talks about viruses quite a bit in this recent interview... https://www.youtube.com/watch?v=Sq7uVZ_0D3U Specific time points listed in the show notes... https://www.foundmyfitness.com&#x
26.
by dpatrick86 8y ago
6:30AM is just some other city's 11:30AM... the difference in between is just light exposure, food consumption, and activity (the three big zeitgebers). Unless you think you'd never resynchronize after moving across the world, it&
27.
by dpatrick86 8y ago
It really sounds like a software issue to me. If the watch is causing atrial fibrillation to be detected too often, then you can either make the software meet some greater threshold before alerting the user.. or, even better, determine more
28.
by dpatrick86 8y ago
Valter Longo's work has shown that fasting causes a destruction of immune cells that get renewed from progenitors (absent the autoimmunity) after the refeeding phase. The mechanism has been shown to help with an animal model of multipl
29.
by dpatrick86 8y ago
Very interesting to hear your successes in light of the immune cell turnover effect that prolonged fasting seems to have (Valter Longo's research). FYI: these episodes also have a transcript and show notes not available at the youtube
30.
by dpatrick86 8y ago
Transcript and other resources available here. https://www.foundmyfitness.com/episodes/guido-kroemer Thanks for sharing!

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