aaauaucuggaa

17 ms·

1. 1.▲
   by aaauaucuggaa 2y ago

   Generally speaking: - Delivery: getting the mRNA and guide RNA into the target cells - Expression: ensuring the target cell expresses the mRNA, thus making the protein - On Target Editing Efficiency: ensuring the intended edit happens at a
2. 2.▲
   by aaauaucuggaa 3y ago

   If working in python, Pint is an excellent choice: https://pypi.org/project/Pint/
3. 3.▲
   by aaauaucuggaa 3y ago

   There is still time, we are very, very far away from "we can genetically modify everything".
4. 4.▲
   by aaauaucuggaa 3y ago

   I got some great advice when I first started coding / CS classes. "Skip Eclipse, use Dr. Java. Skip the intellisense and autocomplete at first so you can really learn". I've kept that mindset for all of my coursework and
5. 5.▲
   by aaauaucuggaa 3y ago

   Thank you very much for sharing these links, a SNP id and browser link was exactly what I was looking for!
6. 6.▲
   by aaauaucuggaa 3y ago

   > What's the risk of lab leak? I think you are latching onto the whole Sars-Cov2 concept here, but it is really a completely different situation. These lipid nanoparticles are highly unstable and require freezing, careful handling,
7. 7.▲
   by aaauaucuggaa 3y ago

   I think you might be over estimating how effective these technologies are. Even in the most controlled circumstances, the amount of actual specific editing which occurs is probably quite low. Off target edits are likely also occuring. The f
8. 8.▲
   by aaauaucuggaa 3y ago

   Hop on the slack, there are plenty of folks (myself included) who are happy to help get you started. I found prefect after slogging through a year of painful development work on an Airflow project, and I have been a rabid fan of it ever sin
9. 9.▲
   by aaauaucuggaa 4y ago

   Your answer is much better
10. 10.▲
    by aaauaucuggaa 4y ago

    With DNA sequencing?
11. 11.▲
    by aaauaucuggaa 4y ago

    Sure, feel free to drop me am email at kylem at mammothbiosci.com
12. 12.▲
    by aaauaucuggaa 4y ago

    I will add Mammoth Biosciences to the list. We are looking for Software Engineers, Data Engineers, Data Scientists and more. https://mammoth.bio/careers/
13. 13.▲
    by aaauaucuggaa 4y ago

    Start with downloading SRA toolkit: https://github.com/ncbi/sra-tools/wiki/02.-Installing-SRA-To... Find some data of interest: https://www.ncbi.nlm.nih.gov/sra?term=(%22Homo%20sapiens%22[...
14. 14.▲
    by aaauaucuggaa 5y ago

    Yes! Thank you!
15. 15.▲
    Ask HN: New Platform for Software Tutorials

    10 points by aaauaucuggaa 5y ago|2 comments
16. 16.▲
    by aaauaucuggaa 5y ago

    a few examples that come to mind: EC2, EMR, ECR, EKS, RDS, EBS, DMS, ECS, VPC, SSS (S3), SNS, SES, IAM,
17. 17.▲
    by aaauaucuggaa 5y ago

    Prions are in a very different category then these 2, which are closer to humans phylogenetically then bacteria are. If they were present (some likely are) in these samples, they would be easily found in the NGS data.
18. 18.▲
    by aaauaucuggaa 5y ago

    Mammoth Biosciences | https://mammoth.bio/ | Full Stack Software Engineer, Data Scientist | Brisbane, CA | Full-time | ONESITE or REMOTE We are a small software team supporting our in-house labratory and research teams as t
19. 19.▲
    by aaauaucuggaa 7y ago

    Super exciting launch! Always good to see more bio companies in YC. I applied for an engineering position and would love to know more about what challenges are being tackled on the software/bioinformatics front.
20. 20.▲
    by aaauaucuggaa 7y ago

    Hopefully picked the right isoform!
21. 21.▲
    by aaauaucuggaa 8y ago

    is REMOTE okay for all of these positions? I applied to St. Jude's awhile back and indicated that I would not relocate (was hoping to be remote) and never heard back.