5 ms·
Generally speaking: - Delivery: getting the mRNA and guide RNA into the target cells - Expression: ensuring the target cell expresses the mRNA, thus making th
by aaauaucuggaa 2y ago
Generally speaking:
- Delivery: getting the mRNA and guide RNA into the target cells
- Expression: ensuring the target cell expresses the mRNA, thus making the protein
- On Target Editing Efficiency: ensuring the intended edit happens at a high rate
- Off Target Editing: ensuring other edits in other locations do not occur
- interestinghiv 2y ago[flagged]
- agnokapathetic 2y agomRNA vaccines are about getting mRNA into just a few non-specific cells which then instructs the cell to produce Corona Virus Spike Protein. This gets identified by the immune system which then makes antibodies targeting the spike protein. So the mRNA only needs to get taken up by a few cells to produce an immune response. The HIV CRISPR-Cas technique needs to target several orders of magnitude more cells in the body, and is performing a far more complicated procedure than simple transcription like with an mRNA vaccine.
- Brian_K_White 2y agoThe covid vaccines weren't crispr. Keep trying soldier.
- Terr_ 2y ago"Good soldiers follow orde^H^H^H^H talking-points." (To wit, I bet someone heard "the vaccine rewrites your DNA" bullshit again somewhere, so it must be true...) https://hcrl.wustl.edu/claims-that-mrna-vaccines-change-human-dna-are-back/ https://hcrl.wustl.edu/claims-that-mrna-vaccines-change-huma...
- tjpnz 2y agoAnd that Bill Gates wants to use the vaccine to depopulate Earth, and that the vaccine includes a 5G enabled microchip to coerce you into adopting SDGs. It's really bullshit all the way down.
- IntelMiner 2y ago"the narrative" [High pitched dog whistle noise]