5 ms·

Sources?

__MatrixMan__ 2y ago
Anecdotal, but I've tripped with two people who showed seizure like symptoms that they never had before or since. Couldn't find any data at the time. Tried to get them to submit experience reports on erowid so that there would be some data out there, but they didn't want to put anything about it in writing.
- mistrial9 2y ago
  ok - an underweight 20 year old woman who did not eat well before a Rolling Stones concert and then used cocaine and alcohol, also had a seizure. goddam Mick Jagger !
- foobiekr 2y ago
  Are you sure shrooms? If chocolates or gummies the compound therein is not quite the same as recent news stories have noted.
  - __MatrixMan__ 2y ago
    Yeah, I grew them. I didn't sequence them for identification, but they were phenotypically P. Cubensis, as advertised on the spore syringe. In neither case was it a big deal in the long run (not exactly great vibes in the short term though). I used to be a pretty enthusiastic user, so "just two times" is indeed uncommon. Hopefully with the recent trend of decriminalization we can get together some respected data about this sort of thing. I still believe that psilocybin has been a net positive thing for most people who have tried it (including these two cases). Even if the seizure thing were confirmed, all the conventional wisdom re: tripping remains unchanged. Be in a safe place with trusted people, consider a trip sitter, etc. On the other hand, I think having the data might help drive some better decisions: Situations you might avoid (e.g. swimming), etc.
  - greentxt 2y ago
    Can I get a cite on one of those news stories?
- muzani 2y ago
  Yeah, I think data on this would be hard to get. A tangential anecdote... I took a Pfizer COVID booster vaccine and saw my heart rate go up to resting above 100 on my calorie tracker watch. I talked with my doctor about this. He said he stayed away from the COVID boosters because they weren't a good balance of risk vs safety. I asked him whether high resting heart rates were a side effect. He said, no, there's no data for that, but there is data that it has an impact on heart rates. I said, if there's no data, that means the vaccine isn't the source? He said, no, there's no data because I didn't report it.
  - SoftTalker 2y ago
    > I took a Pfizer COVID booster vaccine and saw my heart rate go up to resting above 100 Temporarily or permanently?
    - zdragnar 2y ago
      My brother has this permanently, though whether a delayed reaction to the booster or from when he got COVID itself (a relatively mild case) not long after, there's no way to know. It has been a major detriment to his day to day life though. Any physically involved hobbies are impossible; just walking up a flight or two of stairs now leaves him completely winded for several minutes, as his heart rate also takes longer to come back to resting than before. Would not recommend.
      - im3w1l 2y ago
        Maybe it's running at high rate to compensate for some issue? An issue that could be found and resolved?
        zdragnar 2y ago
        He's seen all the specialists. I think they ultimately came down on neurological damage, and tried a battery of drugs until they found some that slightly mitigated the problem. Last we talked about it, though, it hasn't been fully resolved.

Sources?

Anecdotal, but I've tripped with two people who showed seizure like symptoms that they never had before or since. Couldn't find any data at the time. Tried to get them to submit experience reports on erowid so that there would be some data out there, but they didn't want to put anything about it in writing.

mistrial9 2y ago
ok - an underweight 20 year old woman who did not eat well before a Rolling Stones concert and then used cocaine and alcohol, also had a seizure. goddam Mick Jagger !
foobiekr 2y ago
Are you sure shrooms? If chocolates or gummies the compound therein is not quite the same as recent news stories have noted.
- __MatrixMan__ 2y ago
  Yeah, I grew them. I didn't sequence them for identification, but they were phenotypically P. Cubensis, as advertised on the spore syringe. In neither case was it a big deal in the long run (not exactly great vibes in the short term though). I used to be a pretty enthusiastic user, so "just two times" is indeed uncommon. Hopefully with the recent trend of decriminalization we can get together some respected data about this sort of thing. I still believe that psilocybin has been a net positive thing for most people who have tried it (including these two cases). Even if the seizure thing were confirmed, all the conventional wisdom re: tripping remains unchanged. Be in a safe place with trusted people, consider a trip sitter, etc. On the other hand, I think having the data might help drive some better decisions: Situations you might avoid (e.g. swimming), etc.
- greentxt 2y ago
  Can I get a cite on one of those news stories?
muzani 2y ago
Yeah, I think data on this would be hard to get. A tangential anecdote... I took a Pfizer COVID booster vaccine and saw my heart rate go up to resting above 100 on my calorie tracker watch. I talked with my doctor about this. He said he stayed away from the COVID boosters because they weren't a good balance of risk vs safety. I asked him whether high resting heart rates were a side effect. He said, no, there's no data for that, but there is data that it has an impact on heart rates. I said, if there's no data, that means the vaccine isn't the source? He said, no, there's no data because I didn't report it.
- SoftTalker 2y ago
  > I took a Pfizer COVID booster vaccine and saw my heart rate go up to resting above 100 Temporarily or permanently?
  - zdragnar 2y ago
    My brother has this permanently, though whether a delayed reaction to the booster or from when he got COVID itself (a relatively mild case) not long after, there's no way to know. It has been a major detriment to his day to day life though. Any physically involved hobbies are impossible; just walking up a flight or two of stairs now leaves him completely winded for several minutes, as his heart rate also takes longer to come back to resting than before. Would not recommend.
    - im3w1l 2y ago
      Maybe it's running at high rate to compensate for some issue? An issue that could be found and resolved?
      - zdragnar 2y ago
        He's seen all the specialists. I think they ultimately came down on neurological damage, and tried a battery of drugs until they found some that slightly mitigated the problem. Last we talked about it, though, it hasn't been fully resolved.