xab31

8 ms·

1.
by xab31 5y ago
Lots of condescension here, but supposing that overnight returns are in fact on average substantially greater than intraday returns, what is the layman-friendly, non-conspiracy-theory explanation of this phenomenon?
2.
by xab31 5y ago
Well, I do aging research (mostly from a computational+biochemical perspective). I've met most/all of the important players in the field, and it baffles me how this important area of research continues to be a backwater, as far as
3.
by xab31 5y ago
The problem is that if you communicate to the public at the level of normal scientific certainty -- with all the methodological and statistical caveats -- it's very hard to generate the moral authority needed to push sweeping mandates
4.
by xab31 5y ago
> "...Scientists go looking for trouble." It is several repeated and very costly attempts that I made to do just that which leads me to give the advice I did. The pyramid quote is an interesting one. Obviously there is a tensio
5.
by xab31 5y ago
It's a good question, and I don't like posting excessively long comments and didn't have time to make it concise, so here's an attempt at an answer: https://pastebin.com/fsrTtiKY I think science is too b
6.
by xab31 5y ago
Very early on, I noticed that graduate students tend to be idealistic, postdocs extremely cynical, and faculty ruthlessly pragmatic perhaps to the point of occasional shortsightedness. Clearly, something about this progression is expected a
7.
by xab31 5y ago
My big eye-openers (some from postdoc) were more about the sociology of science than the day-to-day productivity: - Even the most blatantly wrong and illogical published work can only be displaced by another publication that explains/d
8.
by xab31 5y ago
Thanks to you, and others, for sharing. I hadn't yet resorted to looking in the consumer space. In research (and presumably clinical)-land, the costs are substantially higher. I'll be looking into it further to figure out whether
9.
by xab31 5y ago
I work in an adjacent area and agree this is all good advice. OP, how did you even get the sequence to begin with? I have a friend who has an immunodeficiency which is almost certainly due to a rare genetic disorder and want to do a very si
10.
by xab31 5y ago
So, we have a climate crisis, uncontrolled health care and college costs, decades of pointless war, mass incarceration, and a variety of other crises that cause a lot of death and suffering. Yet isn't it strange that the one crisis we
11.
by xab31 5y ago
One of our graduate students is thrilled about this paper, although he tends to do that with any new CS advance that seems sensational and that we barely understand (we do bioinformatics). He said that it stood to reason that if it can mmul
12.
by xab31 6y ago
My gut reaction if I were Jeremy would be to say that "This is absolutely absurd; there is no way that claiming 'X's opinion is wrong' is in itself a CoC violation, and if it somehow is, then the CoC is ridiculous. The f
13.
by xab31 6y ago
Yes, I think you're right. He refers to " the two reporters" (and previously mentions that there were two complaints).
14.
by xab31 6y ago
EDIT: My reading was wrong, see below. The thing that seemed to me oddest about all this is that Jeremy says the committee spoke to two reporters before hearing his side of the story, and before issuing a judgment. It is not totally clear
15.
by xab31 6y ago
It was a very effective response from Jeremy. He clearly describes his side of the story and convincingly explains why he thought he did nothing wrong. What is a little more troubling is that he (A) describes codes of conduct in detail and
16.
by xab31 6y ago
> The issue, amazingly, is Fox News and it’s ilk. Yet, the conversation here is the NYT. That is because practically everyone on HN agrees Fox is bad, biased, etc. Therefore the debate is going to be implicitly about how bad the NYT is i
17.
by xab31 6y ago
It's still used quite heavily in research also (medical is what I'm familiar with). NCBI puts a lot of critical data on FTP, as do individual researchers. In the case of NCBI, the actual transfer protocol usually used is Aspera, b
18.
by xab31 6y ago
Interesting because in the original post, he declares his resolve to quit HN and declares that he's not visited it in one whole month . "Yeah, right", I thought, and indeed in the intervening 3 years, he came back. I'd
19.
by xab31 6y ago
Seconded. I work as a data analyst in medical research (bioinformatics postdoc). I am often introduced as a statistician, even though I'm not, because I can do a bit more than a t-test. The situation in research is exactly as you descr
20.
by xab31 6y ago
Even middle schoolers are taught that there are "reliable sources" and "unreliable sources". Wikipedia (pretty good usually) is not considered a reliable source, let alone Twitter or Facebook. Even a reliable source, lik
21.
by xab31 6y ago
> I'd gently suggest that, were you to look around, you'd see others behaving in similar manner; but, for whatever reason, you are noticing it more with this chap...confirmation bias. I agree, I'm well aware of the possibi
22.
by xab31 6y ago
Not sure if this will help, but I'll share my very recent story of how ageism looks from the other (youngish people) side, which contains some pitfalls to avoid. I'm 32, and the technical lead of a mid-sized research computing &#x
23.
by xab31 6y ago
> I do have to comment that the diction used is a bit dramatic. Fair. I wouldn't use this kind of language when talking to colleagues in person, for sure. In fact, I wouldn't address the subject at all. > But, at the same ti
24.
by xab31 6y ago
To avoid giving the impression that I had a horrible advisor who twisted me into cynicism, I should say: My advisor was definitely one of the "idealists". I was his first graduate student. He always treated me well, with respect a
25.
by xab31 6y ago
> An effective PhD advisor/thesis isn't wandering the woods to find something. It's a guided coaching exercise, with an outcome in mind. There is a tradeoff here. One of Eric's selling points for his lab is obviously
26.
by xab31 6y ago
Hard disagree. I made every possible mistake that can be made related to being too idealistic about grad school; for example, I believed: - My advisor and collaborators have my best interests at heart - My primary role in graduate school is
27.
by xab31 6y ago
Well, if the AI turns out to be benevolent, it could end aging and disease, enable interplanetary or interstellar travel, end all relevant forms of scarcity, and liberate us to focus on artistic or hedonistic pursuits for our 10,000-year li
28.
by xab31 6y ago
Unpublished data, I'm afraid, from a collaborator. But the manuscript is very close to submission. I'd expect to see it in 3-6 months. It is honestly very hard to know about this kind of thing, because the results can vary based o
29.
by xab31 6y ago
Thanks very much for that correction. I have no idea how I got the idea that the Commonwealth is so much smaller than it is. So I retract the points I made based on that false assertion.
30.
by xab31 6y ago
Unfortunately the relationship between clock readouts and actual health state is tenuous at best, and is really more of a postulate than an established fact. It is true that Horvath and others have shown that clock deltas (between predicted

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