toufka

6 ms·

1.
by toufka 8d ago
The new iOS rebrands Gemini as Siri - and from all accounts of the public beta, it's pretty decent, and an enormous upgrade from the current/old Siri.
2.
by toufka 1mo ago
I'm guessing - probably some textual variation on Benford's law? [1]. Trivial for compute, painful for a human. - "Ensure distribution of vowels is in >99th percentile of human work" - "Ensure the distribution of
3.
by toufka 1mo ago
The image size of this camera is unbelievably huge in its coverage. Most telescopes take pictures of objects - this one takes pictures of the entire sky. And will do so in a time-lapse fashion for 10 years. It's simultaneously more in
4.
by toufka 3mo ago
Also the fact that the president’s daughter, son in law, and his brother have a significant amount of their net worth invested in OpenAI via Thrive.
5.
by toufka 3mo ago
The administration is not known for taking into account second order effects. The instantaneous instinct to strike an opponent when one can is not much more contemplated than that.
6.
by toufka 3mo ago
How much did Apple (via Google (via xAI (via SpaceX))) just crush their product? Seems an awful lot like Apple will commoditize the models that power Siri, and just “sherlocked” a trillion dollar private company.
7.
by toufka 4mo ago
A large and rapidly growing number. The largest commercial classes of multi-domain therapeutic proteins include the crispr (and similar) that drive gene therapies, and the chimeric antigen receptors (and similar) that drive cell therapies.
8.
by toufka 4mo ago
I mean, the most cutting edge of iPhones, iPads and MacBook Pros _today_ are quite capable of running in realtime today’s high-end local LLMs. If you project out that hardware just a couple of years, and the trained models out a couple of y
9.
by toufka 7mo ago
1) Another OpenAI cofounder (Brockman) gave Trump’s superPAC the largest ever individual donation of $25m. 2) Trump’s son in law (Kushner) has most of his net worth wrapped up in OpenAI.
10.
by toufka 2y ago
A representative idea: if you are the one to kill a deer to eat, you get a little bit of each cut - rib, loin, filet, heart, etc. When was the last time most people ate a filet mignon? And if you gather food like berries and fruits - you (a
11.
by toufka 2y ago
What about the heterogeneity of the original cells?
12.
by toufka 2y ago
Yep - cells would die. ...UNTIL they accrue enough dna damage to accidentally either: - create a new way to generate thymidine - fall into a proliferation strategy that no longer needs thymidine Human cells did the same thing and created ch
13.
by toufka 2y ago
And that’s why replies are helpful in these kind of explanations. My over-edits became wrong, and then an hour later, unfixable. bglazer is correct. AAVs, unlike Lentiviruses, do NOT integrate.
14.
by toufka 2y ago
If the DNA is in the cell's nucleus, the DNA will be utilized to produce whatever gene is encoded in the DNA. But if the DNA is just floating around on its own it will not survive a cell division event and the material would need to b
15.
by toufka 2y ago
Timestamp in the videos: 21:03-4:33 => 7.5hrs
16.
by toufka 3y ago
There’s one law of physics difference here: (with a few exceptions) helium, because it’s lighter than air, will never replenish on our planet. There is currently most of what there ever will be. Unlike (almost?) every other object of commer
17.
by toufka 3y ago
and youtube video of the 'reveal': https://www.youtube.com/watch?v=n--zawliqvA
18.
by toufka 3y ago
Indianapolis was too fast and hot that one year, one of the (two) tire manufactures disqualified their tires (and teams). So not even half the field ran the race. The Indy 500 course has a half-mile straightaway which allowed the F1 cars
19.
by toufka 3y ago
Snowden also brought the goods (actual docs) so that the existing cases and inquiries could proceed without getting the Glomar response - “cannot answer the question of whether you have standing, as we can neither confirm nor deny the progr
20.
by toufka 3y ago
You (at least) have 3 systems that are optimized in concert in a (our) DNA/Protein world. DNA base set, Amino acid set, Translation layer between DNA/Proteins. Currently, we've got: 4 DNA bases, 3 bases/AA, 20 AAs; 4^3 =
21.
by toufka 3y ago
BUT, if you look at the codon table, precisely because it's base-4 and not base-3, many base flips are silent when coded. By using base-4, there's enough space to permit lossiness of the coding itself - given the number of amino a
22.
by toufka 4y ago
Which is why an enormous number of people will be fired, furloughed or reduced to minimum wage on Monday if this isn’t resolved.
23.
by toufka 4y ago
And in this case, tech savy individuals are willing to send $XXM in 6 clicks, 3min after getting a slack message. That's a pretty quick kind of run relative to old-school 'stand in line for your personal life savings' kind o
24.
by toufka 4y ago
The quotes seem to be OCR’d with 500 being 5oo, and punctuation in weird spots too.
25.
by toufka 4y ago
It seems “simple” from a chemistry perspective. But as pointed out, the special part is that this is simple chemistry, _that also works in standard biological conditions_ without harming biology: bio-orthogonal. So it allows complex chemis
26.
by toufka 4y ago
Deere bought the startup Blue River for $300M. Drones to identify and specifically spray just them. Not quite mechanical removal, but closer than spraying the whole field: https://medium.com/@dcvc/john-deere-acquires-bl
27.
by toufka 4y ago
This is an unhelpful article because it straw-mans every argument, and mischaracterizes the primary material. > More recently, Bostrom has said that "unrestricted altruism is not so common that we can afford to fritter it away on a
28.
by toufka 4y ago
“Don't it always seem to go That you don't know what you've got Till it's gone They paved paradise And put up a parking lot”
29.
by toufka 4y ago
There are opposite versions of that story where the drug is a specialized 1-off custom living biological product (often a patient's own engineered immune cells). An entire company's years of effort and existence are tightly coupl
30.
by toufka 5y ago
And the numbers themselves that can be entered manually. 5 payment modalities with a thin piece of plastic.

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