stenl

5 ms·

1.
by stenl 1mo ago
Done, enjoy! I posted links to his web site instead of Sotheby’s. Even though his web site is a little broken, it had much more detail on the technical process, which I think HN will appreciate. https://news.ycombinator.com/
2.
Self reflected, spatiotemporal brain art by Greg Dunn(gregadunn.com)
3 points by stenl 1mo ago|1 comments
3.
by stenl 1mo ago
Greg A Dunn, neuroscientist turned artist, uses microetching to encode time as a third dimension in his artwork. This piece ”Self reflected” is a depiction of the flow of signals in the human brain, which come to live as you shine light on
4.
by stenl 1mo ago
Related: ”Self Reflected” by neuroscientist and artist Gregg Dunn, https://www.sothebys.com/en/articles/self-reflected-a-giant-... He uses the third dimension to encode time, so that you get an image of the brain
5.
by stenl 2mo ago
This seems to be the original: https://s3.amazonaws.com/b2icontent.irpass.cc/2660/rl168199.... (via CBS News: https://www.cbsnews.com/news/truth-api-trump-media/ ) So it seems to be preci
6.
by stenl 5mo ago
My group published a cell atlas of the developing human brain in 2023, giving gene expression in single cells from postconception week 5 to 13. It’s on github: https://github.com/linnarsson-lab/developing-human-brain T
7.
by stenl 11mo ago
He was not head of state when the crime was committed and he is not head of state now.
8.
by stenl 1y ago
If, like me, you wanted to see the actual farthest distance photo, here it is: https://beyondrange.wordpress.com/
9.
by stenl 1y ago
The average federal tax rate is 14%, and the USAID budget was about 0.8% of the federal budget, so you’ve been paying about a 0.1% tax to fund USAID.
10.
by stenl 1y ago
A much more detailed and thoughtful (and peer reviewed) take on the same question from my colleague Jussi Taipale: https://www.embopress.org/doi/full/10.15252/embj.201696114
11.
by stenl 2y ago
Cool! Has anything similar been attempted in tumor tissue, given the many claims of microbes in tumors? Especially tumors not in contact with the exterior.
12.
by stenl 2y ago
And further down: ” Contributions J.J. and D.H. led the research. J.J., R.E., A. Pritzel, M.F., O.R., R.B., A. Potapenko, S.A.A.K., B.R.-P., J.A., M.P., T. Berghammer and O.V. developed the neural network architecture and training. T.G., A.
13.
by stenl 2y ago
These cells won’t divide because they will fail to replicate their DNA due to the lack of thymidine. The use case is cell therapies, where you give the patient cells grown in the lab but you don’t want those cells to potentially divide and
14.
by stenl 2y ago
TERT activation is one of the most common alterations causing cancer. In fact, the whole point of the normally very low TERT expression in somatic cells is likely to be cancer prevention. It’s the mechanism behind the Hayflick limit, which
15.
by stenl 2y ago
Freezing and thawing organoids is not new, it’s fairly routine. The frozen piece of brain from an epilepsy patient doesn’t retain ”normal function”. There is no evidence in the paper that it integrates into neuronal circuits (this was not e
16.
by stenl 2y ago
”The Emperor of all Maladies” by Siddhartha Mukherjee is fantastic
17.
by stenl 3y ago
Related: Dijkstra, ”Why numbering should start at zero” https://www.cs.utexas.edu/users/EWD/transcriptions/EWD08xx/E...
18.
by stenl 3y ago
No that would be amazing. But we don’t have the technology to map all the connections in large mammalian brains. It was done in the fruitfly just this year: https://www.science.org/doi/10.1126/science.add9330
19.
by stenl 3y ago
None, that was done 100 years ago, e.g. by Ramon y Cajal (Nobel prize 1906). But microscopic detail does not give molecular detail. What these current studies add is data on gene expression (mRNA molecules), chromatin accessibility (related
20.
by stenl 3y ago
Papers are paywalled but most can be found on bioRxiv, e.g. https://www.biorxiv.org/content/10.1101/2022.10.12.511898v1
21.
by stenl 3y ago
That’s not a terrible summary of the one paper, but there are 20 more papers. An overview by the Science editor: https://www.science.org/doi/full/10.1126/science.adl0913 The full collection of papers is linke
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A Quest into the Human Brain(science.org)
1 points by stenl 3y ago|0 comments
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A comprehensive census of brain cell types(science.org)
1 points by stenl 3y ago|1 comments
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The Gadget Guru’s Homepage(bobtomalski.com)
2 points by stenl 3y ago|0 comments
25.
by stenl 4y ago
Yes, but at the same time most inbred strains have genetic disorders precisely because they are inbred. E.g. the most commonly used strain C57BL/6 develops age-related hearing loss. To avoid this, there are other lab strains like CD-1,
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by stenl 4y ago
Salmon and cod are both delicious.
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by stenl 4y ago
Boston Globe did a long, thoughtful writeup of the whole affair a while ago, for those interested in more nuance. https://apps.bostonglobe.com/metro/investigations/spotlight/...
28.
by stenl 4y ago
John PA Ioannidis, one of the authors of that paper (which is from 2018 btw) has published an average of 60 papers per year for the last decade, and more than 1100 in total ( https://pubmed.ncbi.nlm.nih.gov/?term=Ioannidis+JP
29.
by stenl 4y ago
Some observations in support, by researchers at Yale: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4167193
30.
by stenl 4y ago
I have this glass sphere model of the universe [1] showing galaxies as tiny bubbles. It’s beautiful and humbling (it represents about 1/100 of the observable universe). [1] https://www.cinks-labs.de/products/the-un

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