skosuri

8 ms·

1.
by skosuri 3y ago
Aspartame breaks down in the digestive track and doesn't enter circulation. It breaks down into three well known compounds that are found in much greater amounts in our natural diets, phenylalanine, aspartic acid, and methanol. The am
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by skosuri 4y ago
I am a founder of a startup (Octant - a16z backed) that has a small & growing software engineering and data science team (see the Nov who's hiring post). Some thoughts on some of the discussion here: 1. Compensation – In academia,
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by skosuri 4y ago
Octant | Software Engineer | Full-time | ONSITE Emeryville, CA | https://www.octant.bio/ Octant is a well-backed (Largest investor is A16Z) team of experienced technologists and entrepreneurs at the frontiers of biology, ch
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by skosuri 5y ago
I imagine how hard this must be on you and your family and kudos for having the energy and wherewithal to try to organize. I think there are a few people/places that might be worth reaching out to in order to learn more. 1. AllStripes
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by skosuri 5y ago
Very little drug development happens in academia. You are missing all the time, money spent in public and private markets in the biotech ecosystem that Pharma largely is the back end buyer for through off-balance sheet acquisitions/dea
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by skosuri 5y ago
Congrats @jrkelly and team! Exciting day for synthetic biology, and love the pictures of the NYSE: https://twitter.com/Ginkgo/status/1438837881649381377?s=20
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by skosuri 5y ago
Yay! Come work with Nicholas, he’s awesome. I’m a cofounder at Octant and feel free to reach out to me as well (dm here or sri@ the same email address). Also, if you are interested in what some of our SWE/ML interns have done over the
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The human genome is finally fully sequenced(biorxiv.org)
5 points by skosuri 5y ago|0 comments
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by skosuri 6y ago
Jesse Bloom of the Hutch is giving a talk tomorrow on the functional consequences and antibody escape about escape mutations in SARS-CoV-2; these are his slides. The talk tomorrow at HHMO can be found here: http://janelia.org&#x
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Interpreting the evolution of SARS-CoV-2(slides.com)
7 points by skosuri 6y ago|2 comments
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by skosuri 6y ago
For the last twenty years I thought things would eventually just come back to center. I’m not sure anymore. It’s possible it’s as follows: One side will win. History will be written by those winners. Pick your side and fight for it?
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by skosuri 6y ago
People have used electron diffraction using cryo-em scopes to do sub-angstrom resolution. For example, my colleague Jose Rodridguez published this a few years ago. https://www.nature.com/articles/s41594-017-0018-0
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by skosuri 6y ago
Lol. Totally agreed.
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by skosuri 6y ago
Totally agreed with you Re: teaching. I think universities are systematically not valuing teaching enough in my opinion. That said, at my university (UCLA), if you are a great teacher, teaching large, popular and impactful classes; you will
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by skosuri 6y ago
What would you propose as an alternative to peer-feedback? I really enjoyed academia and didn't find it soul sucking. Does it suck to get rejected sometimes? Yes. Does the work eventually get out; yes? With pre-prints these days, most
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by skosuri 6y ago
Agreed with this. One big thing that is missing here is teaching. If you are an amazing teacher, things will be much better for you longer term. You will also enjoy the job a lot more.
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by skosuri 6y ago
Post-tenure? Peer-recognition & Funding.
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by skosuri 6y ago
>>And this is it. A reward system based on paper publishing and conference speeches is fundamentally broken. What should it be based on? Should academics be judged on performance? If so, how?
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by skosuri 6y ago
I don't know. I think people overblow this publish or perish thing. Shipping something and regularly is a thing that's important to practice; whether in industry or academia. The reason it's important is that both cases, at s
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by skosuri 6y ago
Octant Bio | Software Engineer (Full-stack) | SynBio Platform Engineer | Emeryville, CA | ONSITE | Full-time | https://www.octant.bio/ Octant is decoding biology’s complexity to build better drugs by engineering biology its
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by skosuri 6y ago
Octant Bio | Software Engineer (Full-stack) | Emeryville, CA | ONSITE | Full-time | https://www.octant.bio/ Octant is decoding biology’s complexity to build better drugs by engineering biology itself. We combine large-scale
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by skosuri 6y ago
Class F stock has a variable number of votes? Is that a standard way to keep control amongst the founders?
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by skosuri 6y ago
To be fair, it's mostly people that do this because negative results publishing is rare. There have definitely been papers saying this though; plenty of shade thrown at basically every new method in its infancy with papers saying why t
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by skosuri 6y ago
This. Writing up work is a LOT of work. Doing that for something that's negative, often for unknown reasons is just opportunity cost most of the time.
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by skosuri 6y ago
https://www.ascb.org/publications-columns/presidents-column/...
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by skosuri 6y ago
1. Other than your time, why not preprint it? 2. As an aside, I can't tell you how many times I've tried to work on stuff, it ends up working, and then I find papers and people saying what we did would never work. Sometimes the ig
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by skosuri 6y ago
1. Plenty of scientists do. In biology, medRxiv and bioRxiv are pretty popular. For example, all publications from my lab are first put there (www.kosurilab.org/publications.html). If we have smaller pieces of work, we tend to just ope
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by skosuri 6y ago
Actually, emphasis on the optimism. The Yale work is really well done. Sensitivity is a little low, but people keep ignoring cost, scalability, frequency and ease. This is what is needed for back to work/school applications and the fir
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by skosuri 6y ago
They both work very similar in theory: unpurified saliva with qPCR. Though as far as I know U of I doesn't have their EUA and have not stated they applied.
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by skosuri 6y ago
It's way easier because it's purification free.

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