ryankemper

6 ms·

1.
by ryankemper 5y ago
As an operator you're always making a tradeoff between the "negatives" of a license and the "positives" enabled by the actual software. So for one example, the recent (bait and) switch of Elasticsearch to SSPL effec
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by ryankemper 5y ago
> There’s nothing silly about a novel virus having greater abilities to overcome barriers when compared to other pathogens that humans have had years decades and centuries to develop defenses again. This isn't really quite accurate
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by ryankemper 5y ago
> You are removing roughly 10% of the population in the U.S., or 2% worldwide. These numbers seem way too low if you're talking about the prevalence of people that have been exposed to SARS-CoV-2.
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by ryankemper 5y ago
> Seems like the simplest answer is just "actions that have reduced the spread of one disease have also reduced the spread of another, that's historically less widespread already." This is not the simplest answer, and the
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by ryankemper 5y ago
Actually, what you're saying is untrue. The overwhelming evidence shows that children spread COVID less than adults do. My favorite is this: https://www.nejm.org/doi/pdf/10.1056/NEJMoa2006100?articleTo...
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by ryankemper 5y ago
For context, in India there's about 27,000 deaths per day in a normal year (napkin math: 7.344 deaths per 1000 from https://www.macrotrends.net/countries/IND/india/death-rate , multiplied by the indian po
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by ryankemper 5y ago
> OK, but you can make the same argument for COVID. It seems to me that the slides are at least comparing apples with apples. If you look at the rates of acute side effects to the vaccines, I forget the exact number but it's at leas
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by ryankemper 5y ago
That doesn't compare vaccination to naturalistic rates at all. It just gives rates of reinfection for those with antibodies versus without.
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by ryankemper 5y ago
A coding camp is the opposite of hustling. It's called "bootcamp" for a reason - it's there to impose some structure for those who need it. Also bootcamp is very overhyped. There's some great people that come out of
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by ryankemper 5y ago
What dataset are you referring to?
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by ryankemper 5y ago
Second shot syndrome is apparently worse in the young (20's / 30's) due to the stronger immune response. I wasn't assuming that everyone who gets the syndrome would be asymp. but just that many would.
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by ryankemper 5y ago
> fwiw, new and better better technologies need to get used for the first time, eventually. No-one disputed that, I'm just pointing out that it is a very valid point for someone to say "I have concerns that we're rushing o
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by ryankemper 5y ago
> Difference is that I know person that got COVID in November and now has issues with memory. > I don't know a single person that has that after flue and cold - and those are with us much longer. Look into ME/CFS, whose exis
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by ryankemper 5y ago
The fact that the vaccines create just a single spike protein and the real virus creates much more is actually one of the issues. First: does the rate at which the cells are made to artificially produce spike protein follow a different curv
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by ryankemper 5y ago
(Not the one you responded to) I know what an mRNA vaccine is and the only clearcut answer is that "yes, obviously the long-tail risks of mRNA vaccines could outpace the long-tail risk of COVID-19". The statement is also true when
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by ryankemper 5y ago
> Also don't think the long-tail risk of an mRNA vaccine can be worse then COVID's long-tail risk. It absolutely could, and that should be self-evident. > Also pretty sure risk of death outweighs literally any possible long-
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by ryankemper 5y ago
We've never taken such an attitude for any other endemic respiratory pathogen in existence, and for good reason. It's completely absurd and ignores not only the important health benefits of regular social contact, including direct
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by ryankemper 5y ago
It is true; the PDF linked in the GC has to make a number of assumptions and is very obviously made from a point of bias (which does not invalidate its claims but warrants extra scrutiny). Also it's comparing raw ICU admissions, but th
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by ryankemper 5y ago
> The chance the disease kills you is 1 in 100 It's 6 in 1000 if you listen to the CDC; personally I think the real number is closer to 3 in 1000. That's not too far off from what you said but I prefer being more explicit rathe
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by ryankemper 5y ago
Thanks. To avoid repeating myself: https://news.ycombinator.com/item?id=26799734 TL;DR you can probably s/mRNA/adenovirus vector/g although I will grant that adenovirus vector seems less "experimental&qu
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by ryankemper 5y ago
> It's not dishonest. It's a very adequate answer to the over-simplifying claim above. I would disagree that calling it "rushed, experimental, and not necessary for [the original commenter]" is an over-simplifying cla
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by ryankemper 5y ago
Thanks for the important clarification; I didn't read closely enough. My argument was definitely tailored for the mRNA discussion, although the purpose was more to illustrate the broader principle, but, not knowing a whole lot about ad
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by ryankemper 5y ago
It's extra frustrating because organizations like the CDC get held to lower standards than anyone else. They can make a pronouncement recommending the use of face masks for SARS-CoV-2 community transmission when the body of the researc
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by ryankemper 5y ago
I hear this line being trotted out all over - especially from the "experts" - and I find it nothing short of enraging. There is a difference between saying "an mRNA platform in general might not be safe" and the actual c
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by ryankemper 5y ago
> All these anti-vaxers talking about living in fear of a virus that has 98% survival rate Please cite a source here. Survival rate usually means IFR not CFR, and even the CDC's own number (the CDC is going to be incentivized to ove
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by ryankemper 5y ago
We live in a time in which we've thrown everything we knew about health and immunology out the window and have built a society in which all scientific (or philosophical) dissent to the COVID-19 fear-narrative is censored by large tech
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by ryankemper 5y ago
Traditionally, opioids/opiates kill via mu-opioid receptor agonism, which is why administration of a mu-opioid antagonist (Naloxone, brand name Narcan) is the first line of defense for avoiding mortality. However Fentanyl is unique in
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Non-opioid MoA in Fentanyl explains failure of Naloxone in opioid crisis (2019)(ncbi.nlm.nih.gov)
4 points by ryankemper 5y ago|1 comments
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by ryankemper 6y ago
> And then the site exploded, and it had to learn how to handle things like actual nazis calling for the deaths of jewish people. Oh, so is that why they banned The Donald? Or any of the other number of subreddits they have quarantined
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by ryankemper 6y ago
> Reddit is still very much anti censorship. This is just not true. They are very transparently trying to kick off users/communities that they don't "like". For example basically any subreddit associated with the &quo

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