rdmirza

20 ms·

1.
by rdmirza 1mo ago
We’ve had a bunch of folks express interest (thanks!).. But to be clear: this is an in person (Toronto) / remote hybrid position. If your CV doesn’t have a locale, please confirm your willingness to come in person/relocate
2.
by rdmirza 1mo ago
*Strello Health | Founding Software Engineer | Full-time | Hybrid Remote | Toronto/GTA* Strello Health builds AI voice agents for healthcare. We’re post-seed, generating revenue, and scaling quickly. You’ll work directly with the found
3.
by rdmirza 2mo ago
Aye. Outside edit window unfortunately
4.
by rdmirza 2mo ago
It's established that COVID can persist in tissue/blood - particularly in immunocompromised patients - and is associated with long COVID [1]. This abstract only reports a cut-off of >60 days from COVID infection, so it's h
5.
by rdmirza 8mo ago
Two familial cases of sudden cardiac death? That’s not normal. That’s an indication to investigate.
6.
by rdmirza 1y ago
Your take on Evidence Based Medicine (EBM) is wrong. At the top of the evidence hierarchy is N-of-1 trials (and below that are high quality meta-analyses of trials). Nothing is more informative about treatment response in a person than test
7.
by rdmirza 3y ago
My immediate thought. Big Claims without backing. Your model makes predictions. Prove they’re worth salt.
8.
by rdmirza 3y ago
At that point you’d simply cut out the tumor.
9.
by rdmirza 3y ago
Small individual study sample size does not necessarily mean junk. Junk is a product of poor methodology. The main concern with sample sizes may be overestimates of effects if the event is rare, or poor precision (ie large confidence interv
10.
by rdmirza 3y ago
I think you’re spot on about the clear advantage of your approach relative to the article and blood biopsies: If you’re looking for cancer in the blood, you’re probably too late as this suggests metastatic spread. You suggest something bett
11.
by rdmirza 3y ago
Even better is installing an implantable cardiac defibrillator (ICD) in those at high risk.
12.
by rdmirza 4y ago
The main concern here (and most observational studies) is confounding by indication. Specifically, the same reason some people got hydroxychloroquine as opposed methotrexate is the same reason you see differences in the outcome. In this cas
13.
by rdmirza 4y ago
I'm intrigued about your research and would love to hear more. I'm a physician interested the effect of for-profit care on health care and outcomes. As an example, we showed that for-profit dialysis facilities in the US have about
14.
by rdmirza 4y ago
Yes cholesterol is a vital building block. However the medical literature consistently shows a strong relationship between LDL and non-HDL cholesterol levels and heart attack and stroke. Various cholesterol lowering drugs, statins being the
15.
by rdmirza 4y ago
That’s a great thought, however, when you look at tissue under a microscope you should see evidence that the immune system was at play. This means the presence of complement activation (an ancient arm of the immune system), antibodies, whit
16.
by rdmirza 5y ago
Wow, this is appalling medical advice. Perhaps diet, exercise, and evidenced based treatments would be a good place to start.
17.
by rdmirza 5y ago
This is no longer true. The GLP1s have proven to have excellent efficacy for weight loss (and cardiovascular mortality in diabetics). Their numbers approach bariatric surgery (>10% body weight in the obese). People keep the weight off to
18.
by rdmirza 5y ago
This piece entirely misses the point of the recommendation. The new recommendation is that aspirin should not be used to prevent heart attack in those without a history of heart disease (ie avoid routine aspirin for "primary prevention
19.
by rdmirza 5y ago
My meaning was that there is no other therapeutic agent available for prevention of post-ERCP pancreatitis. But you're quite right, there must be another reason. If I had to hazard a guess, it may be the market isn't attractive en
20.
by rdmirza 5y ago
Ahh, the pricing of rectal indomethacin. Here's the tale: If you have obstruction of your bile ducts below the liver or gallbladder, usually gallstones or sometimes neoplasm, you need an endoscopic retrograde cholangiopancreatography (
21.
by rdmirza 5y ago
I did not bother to read this thread in its entirety though I typically enjoy HN discussion. Undoubtedly, masks of any quality work. Airborne viruses still exist in secretions (likely, in much higher concentrations). Secretions sometimes ev
22.
by rdmirza 6y ago
Compare those values to your own weight, and pay attention when you hear someone’s weight to see if it matches your heuristic.
23.
by rdmirza 6y ago
MAPS (multidisciplinary association of psychedelic studies) is systematically demonstrating the positive effects of psychedelics. Their most impressive work is in PTSD. In Phase 2 trials, they took people with established PTSD (for years) a
24.
Pointed Thoughts about AI
2 points by rdmirza 7y ago|0 comments
25.
by rdmirza 7y ago
This comment is so entirely out of place on HN.
26.
by rdmirza 7y ago
Yes, and no. Yes: the net impact on the environment is likely to be equivalent if imports and exports balance. No: a major criticism of renewable energy is that it is less reliable. Achieving 100% is much more impressive without a handicap.
27.
by rdmirza 7y ago
That's fascinating. Though it's not quite 100% renewable energy unless the energy being imported is also renewable.
28.
by rdmirza 9y ago
This doesn't necessarily change anything about computing neural nets. You need to view the genomic variation as representing the complexity of each neural unit: its connections (in and out), it's propensity to fire, and function i
29.
by rdmirza 12y ago
FMT is already used as a treatment for c. dif here in Canada.
30.
by rdmirza 13y ago
Im surprise that nobody has mentioned that the author here is being sarcastic. The author is clearly being facetious. "How to apply to your own life: When in need, seek sociopathic counsel," do you really think the author means th

More ›