ptest1

5 ms·

1.
Some things I’ve learned about memory(neugierig.org)
1 points by ptest1 5y ago|0 comments
2.
Why not add an option for that?(neugierig.org)
2 points by ptest1 5y ago|2 comments
3.
by ptest1 6y ago
Not only that, but many nonprofits must force their employees and even volunteers to use annoying time tracking software!
4.
by ptest1 6y ago
I was floored to discover Reddit is violating Google’s Auth TOS! Check this out: 1. Log in using your Google account. 2. Log out of reddit. 3. Clear your Reddit cookies. 4. Visit Reddit again. You’ll be automatically logged in..!! This is
5.
Sorry, millennials. The crying emoji isn't cool anymore(cnn.com)
2 points by ptest1 6y ago|1 comments
6.
by ptest1 6y ago
In large dense American cities there are risks with even going outside on a walk. There are stories of people who didn’t leave their homes except on walks but caught COVID-19. There was a NYT columnist who got it and hadn’t done anything ex
7.
by ptest1 6y ago
I added “beside the point” because I believe so, yeah.
8.
by ptest1 6y ago
None of the items were life or death essentials. These were things like protein cookies, pet-themed gifts, exercise equipment, etc. I wouldn’t have bought them if I never saw the ads. But wanting and needing are different things. I wouldn’t
9.
by ptest1 6y ago
I might be one of the few, but I like the ads I see on Instagram and have purchased lots of things via IG ads. I can’t think of any other app/site where the ads have sucked me in. I realize this is besides the point, but I thought it
10.
by ptest1 6y ago
The problem I see with this trial is that it’s open-label, small n, and has subjective endpoints (ICU admission as the primary outcome). The study is underpowered to detect mortality. Given the open-label nature of the trial, the subjective
11.
by ptest1 7y ago
I guess what I think could be possible is: ARBs upregulate ACE2 but within normal physiological limit (see other comment). My understanding is it is the Ang II activation of AT2R that drives the increase in ACE2 expression. In this case, we
12.
by ptest1 7y ago
Just a little clarification. These renin-angiotensin terms are totally confusing (due to how similar they all are!) and from my correspondence with physicians, many of them even get them mixed up! Virus binds to and downregulates ACE2. ACE2
13.
by ptest1 7y ago
As far as I can tell, there are no studies showing a higher ACE2 causes more severe disease. Sure, it could, but the pathophysiological models and animal data suggest that it is the loss of ACE2 that may drive disease severity. There is a
14.
by ptest1 7y ago
I wrote a long comment and it got deleted, argh! Best guess? ACE2 loss is probably bad, having more ACE2 probably doesn’t drive disease severity: https://twitter.com/__philipn__/status/1229568317167243264?s... Rel
15.
by ptest1 7y ago
They won’t block ACE2 but as indicated in the article they may prevent the lung damage associated with SARS by blocking AT1R which is the receptor that may mediate lung damage. There’s lots of discussion and papers collected here: https:&#
16.
by ptest1 7y ago
This wasn’t in a petri dish actually, this was an in vivo study using mice. Other in vivo studies show similar. There are actually no known trials with ARBs and SARS-CoV-2, which is really weird. There should be. One reason why is because m
17.
by ptest1 7y ago
Excessive unrelated business income causes a loss of public charity status due to failing the public support test. In this case it’s moot because ISOC is giving up on their status regardless. I was wrong saying 501(c)3 status is lost- inste
18.
by ptest1 7y ago
(I also work in the nonprofit space) In this case, ISOC should almost certainly lose their 501(c)3 status, as the transaction is unrelated business income, and may or may not have been sold at fair market value (I don’t believe it was). In
19.
by ptest1 7y ago
The mass complaints work very well when backed by an organized effort to lobby, press attention, etc. There are people vulnerable to political and social pressure who make decisions based on this stuff, e.g. the CA attorney general (in the
20.
by ptest1 7y ago
The former CEO of ICANN basically started the PE firm PIR was “sold” to: https://www.privateinternetaccess.com/blog/2019/11/isoc-pir-... ICANN, by lifting the price restriction, was likely “in” on this deal.
21.
by ptest1 7y ago
I’m doing this! Both for PIR and ICANN. Please see my other comment on this thread. It is likely this “sale” could be considered illegal. Here is the information for ICANN which can be used for the above form as well: https://www
22.
by ptest1 7y ago
I don’t understand how this “sale” is legal in the first place. PIR is a legal 501(c)3 nonprofit. You can’t really sell a nonprofit to a for-profit company except in unusual and rare circumstances. In California, I know you need a letter fr
23.
by ptest1 7y ago
Comment deleted because this doesn’t appear to be the right place to discuss nuanced issues about Facebook.
24.
by ptest1 7y ago
I think accessibility is very important, but I share your worry about the future for very small startup projects. I think it’s already almost impossible. I worry about it getting much worse, especially with the animosity the larger tech com
25.
by ptest1 7y ago
Yes, please!!
26.
by ptest1 7y ago
Yeah so you could do a rebase and remove all of the user’s commits, but their work would likely still remain in the subsequent history- integrated as changes in some way. It would be a real mess.
27.
by ptest1 7y ago
Again, the GitHub example is a good one. I have some commits in Django core from years ago. What if I “request” my data be deleted from GitHub? What are they supposed to do? If they rewrite the history it will destroy the project; and if an
28.
by ptest1 7y ago
What I’m saying is that there is more work for startups / side projects to do, not that it’s impossible. It raises the barrier.
29.
by ptest1 7y ago
Besides the tremendous onus laws like this may place on small startups and side projects: Does anyone know how companies are supposed to comply if “user data” literally cannot be deleted? I’m thinking in the case of blockchain type applicat
30.
by ptest1 7y ago
I believe these vaping cases are from using elicit, underground THC vaping products and not the usual e-cigarette / nicotine vaping we usually associate with the word “vaping.” There’s some details over on Reddit: https://ww

More ›