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prefrontal
searching Neon…
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1.
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by
prefrontal
9mo ago
Many thanks - appreciate the kind words. Thanks also for always working to work with care in your science. It makes all the difference. Among other challenges, when we first submitted the poster to the Human Brain Mapping conference we got
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prefrontal
9mo ago
Yeah, it did prove to be a rather one-sided conversation... ;)
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prefrontal
9mo ago
Many thanks! It was a ton of fun. Hard to beleive that we are coming up on 20 years since the data for the salmon was first collected...
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prefrontal
9mo ago
While I would agree that the prevalence of the problem has been minimized in fMRI during the last 15 years, I disagree that our critique does not hold up. The root of our concern was that proper statistical correction(s) need to be complete
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by
prefrontal
9mo ago
When we published the salmon paper, approximately 25-35% of published fMRI results used uncorrected statistics. For myself and my co-authors, this was evidence of shaky science. The reader of a research paper could not say with certainty wh
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by
prefrontal
9mo ago
That was our paper! We showed that you can get false positives (significant brain activity in this case) if fMRI if you don't use the proper statistical corrections. We did win an Ig Nobel for that work in 2012 - it was a ton of fun.
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by
prefrontal
9mo ago
As the first author of the salmon paper, yes, this was exactly our point. fMRI can be an amazing tool, but if you are going to trust the results you need to have proper statistical corrections along the way.
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prefrontal
9mo ago
As the first author on the salmon paper, yes, that was exactly our point. Researchers were capitalizing on chance in many cases as they failed to do effective corrections to the multiple comparisons problem. We argued with the dead fish tha
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prefrontal
2y ago
Pretty much what TeMPOraL said. You can scan pretty much anything with fMRI and find results if you don't use proper statistical corrections. I have found "significant" voxels in a pumpkin before while doing testing. Our argu
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prefrontal
2y ago
> we have a print of the poster on our lab's wall That's amazing - you made my day with that statement. I left neuroscience for the software world back in 2012, so I don't have a lot of data points since then. I know bet
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prefrontal
2y ago
I'm the first author of the salmon fMRI paper, if you have any questions. Generally, how the investigators do their statistics can lead to implausible conclusions. Extraordinary claims should require extraordinary evidence.
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prefrontal
5y ago
I've scanned about 300 people as part of my research career. The director of the imaging center reviewed every anatomical scan. From that group of 300 we informed about three people that they had an anomaly which should be examined by
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prefrontal
5y ago
Marc Abrahams, organizer of the Ig Nobels, asked us for a salmon recipe to include in a cookbook they were publishing. We sent in a single page recipe for how to cook a salmon in an MRI scanner by overriding the safety protocols. That was f
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prefrontal
5y ago
Thanks for the kind words. I am the first author of the "Neural correlates of interspecies perspective taking in the post-mortem Atlantic Salmon: An argument for multiple comparisons correction" paper. Happy to take any questions
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prefrontal
6y ago
My wife and I are so irritated about this. She bought a Cricut Maker last year to make masks for friends and family. Custom images were cut for every person she made a mask for. Now, nine months after we bought the machine, we will have t
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prefrontal
6y ago
As the first author of that paper, I approve of this link.
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prefrontal
8y ago
I cooked it for dinner. We kept it cold in the snow outside the building all day while we worked. Tasted like regular salmon when we ate it.
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prefrontal
8y ago
We just had the one salmon to scan, unfortunately. Regardless of the pre-existing condition of the salmon (zombie, rust, etc) there were no significant voxels of activity once we applied proper statistical corrections. This strongly point
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prefrontal
8y ago
Good question. Ultimately, in fMRI we are looking for changes in the local ratio of oxygenated to deoxygenated blood. As neurons begin firing in a brain region more oxygen-rich blood is dumped in by the circulatory system. If the salmon
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prefrontal
8y ago
At least six, most of them in Cambridge on the night we won the IgNobel prize.
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prefrontal
8y ago
I am the first author of the salmon poster/paper. If you all have any questions I am happy to answer!
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by
prefrontal
9y ago
My wife and I actually ate it for dinner that night!
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by
prefrontal
9y ago
Glad that you found it useful and/or humorous!
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prefrontal
9y ago
We were the inaugural article in what was to be an entire journal dedicated to surprising/odd results. The salmon paper went through a pretty solid peer review as part of publication in JSUR, so we felt good sending it there. Our pape
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prefrontal
9y ago
My grad school advisor and I were always scanning interesting things when we had sequence testing to do. We scanned other objects like pumpkins and such as well. We scanned the salmon since we thought it would look interesting on a high r
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prefrontal
9y ago
Sorry man - the karma train is probably done. We wrote a few other papers on fMRI reliability, but nothing with the popularity that the salmon paper had. There are a huge number of fMRI papers that have significant results, statistically a
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prefrontal
9y ago
We were doing testing for an fMRI experiment that we planned to run with humans later. So, yes, all of the stimuli were presented to the salmon. It only felt a bit ridiculous at the time...
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prefrontal
9y ago
I think it was just asking you to register for Dropbox. If you close that popup the PDF is already open behind it. Here's a link from my server that should just work: http://prefrontal.org/files/papers/Bennet
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by
prefrontal
9y ago
Yeah, actually, we feel like it did serve as a solid illustration as to why proper statistical correction is necessary. We had a lot of emails saying what a useful tool it was for lab meetings and classes. We did a review of the literature
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prefrontal
9y ago
Yeah! One of the other authors on the paper sent it my way right after it was published. Freaking amazing - I love it.
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