packeted

5 ms·

1. 1.▲
   by packeted 3mo ago

   Files are huge for sure (mine are like 25Gb x 3 of us) but Claude Science / Macbook Pro M5 Max knocked out my analyses in minutes using command line tools like bcftools and scripting. Honestly think this opens up WGS data to much easie
2. 2.▲
   by packeted 3mo ago

   Thanks for the kind words. Actually we got the trio whole genome sequencing through our neurologist/geneticist a couple of years ago. It was performed by a company called GeneDx. They interpreted the data at the time which is how we go
3. 3.▲
   by packeted 3mo ago

   Marginally but the data manipulation is actually being done locally as the genome CRAM files are like 24Gb each.
4. 4.▲
   by packeted 3mo ago

   I watched the announcement and gave it a spin as I'm a heavy user of cowork/code. So far I'm super impressed. I used it to analyze my whole genome sequencing data I have as my son has a rare genetic condition. I used it to an
5. 5.▲
   by packeted 7mo ago

   It's been a painstaking process of combing consolidator websites (eg. PetVet Care Centers, NVA) for practice names, verifying and adding them to a list over the course of over a year. I now get many people writing in to report practice
6. 6.▲
   by packeted 7mo ago

   Thanks! Actually I did add the UK very recently but this is a good reminder to improve the UI to make it more obvious, if you go to https://www.privateequityvet.org/vet-list/map.html you can toggle between US and UK. I
7. 7.▲
   by packeted 7mo ago

   I'm working on a website that lists veterinary practices owned by private equity or large corporations to help people make more informed decisions about where they take their pets. It started as a small passion project after our dog (w
8. 8.▲
   by packeted 8mo ago

   I'm looking forward to reading your book! Part of my expose of PE in the veterinary business can be found at https://www.privateequityvet.org
9. 9.▲
   by packeted 8mo ago

   If anyone wants to see how private equity has transformed the veterinary industry check out www.privateequityvet.org/vet-list - over 7000 practices mapped across the US so far. Our dog died at the hands of a recently acquired PE practi
10. 10.▲
    by packeted 1y ago

    Wow, great work. This is the kind of citizen hackery we need in society :)
11. 11.▲
    by packeted 2y ago

    Auricle | Founding Biomechanical Engineer (Neurotech Medical Device) | ONSITE (Mountain View, CA) | Full-time | https://auricle.com Auricle is developing a next-generation neurostimulation implant to restore hearing and the abil
12. 12.▲
    by packeted 3y ago

    Congratulations on the launch, this looks like a super useful product and I'll give it a try. I've been responsible for conducting hundreds of qualitative interviews over zoom in the past and while the insights were very useful, i
13. 13.▲
    by packeted 4y ago

    Auricle | Mechanical Engineer, Simulation Engineer | Mountain View, CA / Remote | Full-time & Internship | https://auricle.com Auricle is a medical device company developing a breakthrough minimally-invasive neurostimul
14. 14.▲
    by packeted 4y ago

    Planet Money is looking for people who have had questionable experiences with BNPL providers, I'd take a look if you haven't already: https://www.npr.org/2022/02/10/1079837232/have-you-used-buy-
15. 15.▲
    by packeted 5y ago

    That's exactly why Tesla are so good at what they do! I've had VW , BMW and Ford rental cars in the last year and they are literally stuck in the dark ages when it comes to on car entertainment and the things that just work and ar
16. 16.▲
    by packeted 5y ago

    Are google workspace accounts treated the same? I have several fill me domains hosted with Google duo curious if this behavior tracks over to their paid products
17. 17.▲
    by packeted 6y ago

    There are a few that I have listed on my website at https://franciswong.com/digital-health although since COVID some have been less active. Take a look at Docs and Hackers, UCSF Health Hub and Stanford's Center for Dig
18. 18.▲
    by packeted 7y ago

    I have the base model MBP 16 inch and I've been experiencing slow downs with laggy keyboard input, momentary freezes, etc. Battery life is also not as good as on my old MPB 13 and I don't use it for much more than browsing with ma
19. 19.▲
    by packeted 7y ago

    You can't beat free. SVB and others get you with free for x months but once their fees and "analysis fees" kick in it really gets quite expensive for a small bootstrapped business even with little activity on your account. It
20. 20.▲
    by packeted 8y ago

    I wanted to read this article especially as I've been to Chateau de Chambord, but this website is the epitome of adverts ruining the browsing experience!
21. 21.▲
    by packeted 8y ago

    I recently listened to The Fountainhead by Ayn Rand and feel that it has changed the way I think. As an entrepreneur who has been in the trenches, I felt a lot of empathy for Roark's uncompromising ideals, his pursuit of excellence, hi
22. 22.▲
    by packeted 8y ago

    I want to love eBay but I can see why the board is so unhappy and the rot has been infiltrating the company for a long time. Back in the 00's I was a PowerSeller, shifting over $20k a month. At first it was an incredible experience and
23. 23.▲
    by packeted 8y ago

    Not very surprising, voice is a terrible interface for buying random products, even more so when you're talking to a dumb computer. It's what people used to have to do decades ago before e-commerce became widespread. That said I c
24. 24.▲
    by packeted 8y ago

    These guys are definitely predatory. I'm a bootstrapped startup founder and I think Prosper caught wind that I have some debt, most likely because I use Credit Karma who I'm sure must sell one's credit information. I now get
25. 25.▲
    by packeted 8y ago

    Loved reading this! I just finished restored a 1912 house in Oakland made out of the same old growth west coast douglas fir - from the framing to the copious clear vertical grain and quarter sawn wainscoting, all stripped, sanded and refini
26. 26.▲
    by packeted 8y ago

    Would be very interested to hear whether this is actually a long-term fix to the problem. I have had this issue many times with my MBP non-TB model, usually resolved by some compressed air under the keys.
27. 27.▲
    by packeted 8y ago

    Awesome. I was playing Batman Arkham City yesterday and this is "Detective Mode" in the real life!
28. 28.▲
    by packeted 8y ago

    Though this was concerning the company who handle our home insurance, also a startup named Hippo, who are great. Thankfully not!
29. 29.▲
    by packeted 8y ago

    Why does Facebook need to give up any of this information to developers in the first place? Presumably these apps are part of the reason Facebook has the engagement it has? Or part of the reason for the user growth it has seen in the past?
30. 30.▲
    by packeted 8y ago

    It's also interesting that there is barely a mention of all this in my news feed on Facebook and there have been no links to it as a trending story.