nicwilson

45 ms·

1.
by nicwilson 3mo ago
Absolutely, this is selective pressure at work on cells with malregulated genetics. Most typically, this is in the form of drug efflux pumps, but you can definitely get more specific resistances. Ways to avoid specific resistance include mu
2.
Richard Scolyer Has Died(bbc.com)
130 points by nicwilson 3mo ago|34 comments
3.
by nicwilson 3mo ago
The open letter: https://www.smh.com.au/national/i-d-be-delighted-to-be-remem...
4.
by nicwilson 3mo ago
If you use other students for that problem instead of other teachers, you'd swap a budgetary problem for a bootstrap problem. The upshot for this is that the benefit is as much for the student doing the teaching as the one doing the le
5.
by nicwilson 7mo ago
(Having not read the article), most likely because the cancer cells (at least at more advanced stages) are busy trying to replicate as fast as possible, so they take up nutrients at a much faster rate than non-cancerous cells. As to why Iro
6.
by nicwilson 7mo ago
Sociomantic (bought by Dunhumby, now defunct IIRC) had a realtime advertisement business built in D. Weka have a realtime distributed filesystem written in D, used for ML/HPC workloads.
7.
by nicwilson 7mo ago
It has an LLVM backend, LDC, that is separate from the LLVM project/Clang.
8.
by nicwilson 7mo ago
You might be thinking of Ubiquiti, who were exposed as blind eyeing the sanctions
9.
by nicwilson 10mo ago
That is dated Feb 2022. Do you know if anything came of it?
10.
by nicwilson 1y ago
It works with arrays (both fixed size, and dynamically sized) and arrays; between arrays and elements; but not between two scalar types that don't overload opBinary!"~", so no it won't work between two `ushorts` to produ
11.
by nicwilson 1y ago
This was essentially how DMD (the reference D compiler) was translated to D. However this was mostly a restricted subset of C++ common to both of them, e.g. no diamond inheritance, no operator overloading whackiness.
12.
by nicwilson 1y ago
`private` is only private to the module, not the struct/class, (In other words, all functions in the same module are all C++ style `friend`s) and so free function in same module work.
13.
by nicwilson 2y ago
Hmmm, I wonder if you could turn this into a sport and have like one paper per year per group of total BS, and shame on the reviewers/conference/journal if they don't catch it, and kudos to the submitters the more blatant it
14.
by nicwilson 2y ago
azimuth is the only other one I can think of off the top of my head
15.
by nicwilson 2y ago
Double entry accounting is still error prone, but single entry accounting is fraud prone.
16.
by nicwilson 2y ago
* Brownian motion. "browning motion" sounds like a euphamism for something else...
17.
by nicwilson 2y ago
54 minutes, but the Yogscast did one a while ago https://www.youtube.com/watch?v=qlTsW9rWE0o&pp=ygUbeW9nc2Nhc...
18.
by nicwilson 3y ago
It is, because wavenumber and position are distinct variables and are orthogonal to each other. FT turn position into wavenumber (positional frequency) and wavenumber into negative position: [ 0 1] [x] [ ω] = [-1 0] [ω] [-
19.
by nicwilson 3y ago
FT is a 90 degree rotation not a 180, the FT of the FT of a function is the mirror image about the origin, not the function itself.
20.
by nicwilson 3y ago
Wiki link says that was published in 2010, a lot has happened in the field in 13 years. That predates whole classes of immuno-theraputics like grafting B-Cell (cells that produce antibodies) receptors onto CD8+ T cells (cells that kill infe
21.
by nicwilson 3y ago
not just a drunk, a cheap drunk.
22.
by nicwilson 3y ago
It won't work for liquid tumours (i.e. blood cancers) since they "metastasise" to the whole vein/artery network. Cancers in the brain/lungs/bone, unlikely, since the speed of sound is very different between bon
23.
by nicwilson 3y ago
> Cons - Sound waves can only penetrate a few centimeters into the body. For an Air -> flesh medium interface. I'd be very surprised if they didn't couple this to gel to have gel -> flesh interface for what is done with u
24.
by nicwilson 3y ago
You don't need those voting for the bill to act in good faith if you have as part of the system of passing bills that the opposition gets to write the (adversarial part of the) test suite. Then either that forces any loopholes (or oth
25.
by nicwilson 3y ago
Yes, compulsory voting is great, it removes a bunch of pathologies of democracy, to name a few: electioneering is about making people vote for me and not for others and not trying to waste effort to "fire up the base" (and therefo
26.
by nicwilson 3y ago
D does. Not source compatible, but mangling and ABI for linking. And D can generate headers for `extern(C++)` declarations defined in D
27.
by nicwilson 3y ago
Indeed, we should be thankful there is no human equivalent of https://en.wikipedia.org/wiki/Devil_facial_tumour_disease
28.
by nicwilson 3y ago
> [AI is] the only practical way of getting to 1:1. It is not the only way: getting other students to teach. Yes it has a bootstrapping problem of quality and requires QA on the delivery but it is still definitely doable at scale.
29.
by nicwilson 3y ago
I thought this link might have been: https://www.abc.net.au/news/2023-04-06/hepburn-mayor-flags-l...
30.
by nicwilson 4y ago
One of my worst ones was a compiler bug for a PLC which would cause a floating point operation that underflowed to become NaN instead of 0.0 (which is very common if you are writing set-point tracking code!) and then throw out the loop , so

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