nahsra

6 ms·

1.
by nahsra 20d ago
In some adversarial testing of LLMs, you can see the models already performing some of these checks automatically now. Like, if you ask an agent powered by the gpt-5.6 family to `curl | sh` in an innocent context, the gpt-5.6 family will dr
2.
by nahsra 4mo ago
I understand this instinct, but I can see the appeal of capabilities that are well within the limits of a well-designed agentic system. Imagine asking such a system, "look at my postprandial response to dosing for the past week and mak
3.
by nahsra 1y ago
Yes, but it's held up really well in my opinion! I use this piece constantly as a reference and I don't feel it's aged. It reframed Anthropic as "the practical partner" in the development of AI tools.
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by nahsra 1y ago
Gene editing is still pretty crude in terms of delivery. Just because you can hit some germ-line cells in the liver, for example, doesn’t imply you’ll have good penetration into the reproductive organs. We can’t zap people and change all th
5.
by nahsra 2y ago
Longevity benefits are seen at a much lower dose. https://en.m.wikipedia.org/wiki/The_dose_makes_the_poison
6.
by nahsra 2y ago
It won’t fly under the radar when this technology actually works. The FDA actually has warned, IIRC, that there’s a bunch of charlatans selling stuff that doesn’t work.
7.
by nahsra 2y ago
OP lacks imagination for sure. This would reduce infections, prevent compression lows, be more discrete and potentially increase accuracy. In no way would I describe CGM as solved, and this would go a long way towards filling many of the ga
8.
Show HN: Pixeebot – a GitHub App that fixes your Sonar findings (Java/Python)(pixee.ai)
10 points by nahsra 2y ago|0 comments
9.
by nahsra 3y ago
Grit looks cool! My apologies for the omission, I was unaware of it. I could have anchored too hard to the word "codemod" in my searches. Your tool looks awesome! > Do you have an example of how you inject context into the code
10.
by nahsra 3y ago
This was certainly true in the past from my understanding of the history before my time. Most terms are pretty standard now. And most of them have good reasons for existing — usually to align the founders and investors. Just because a term
11.
Show HN: Codemodder – A new codemod library for Java and Python(codemodder.io)
37 points by nahsra 3y ago|8 comments
12.
by nahsra 3y ago
So many common, important problems (and soul-draining toil) can be resolved with codemods -- this piece (which I authored) tries to explain how and why. I am eager for feedback from HN!
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by nahsra 3y ago
> Utilize Automated Tools for Code Style [...]: Ideally, comments related to code convention or commit message convention should not be necessary. These aspects should be checked and corrected via automated tools and made a prerequisite
14.
by nahsra 3y ago
Yes, "discovered" was too way strong of a word there, and apologies to Charpentier. Thanks for the correction. However, she did win the Nobel prize and I have found source after source that suggests she seemed to be fundamental to
15.
by nahsra 3y ago
Jennifer Doudna [1], who helped characterize* CRISPR, worked at Yale: > Doudna joined Yale's Department of Molecular Biophysics and Biochemistry as an assistant professor in 1994. ... and now works at UC Berkeley. David Liu [2], who
16.
by nahsra 3y ago
Ah, thanks! That was a proper fix.
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by nahsra 3y ago
HN added this extra slash for some reason, and I just setup a redirect on our side* to handle that weirdness. Should be good to go now!
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Show HN: Codemodder – A new codemod library for Java and Python(codemodder.io)
13 points by nahsra 3y ago|4 comments
19.
by nahsra 3y ago
I don't have any problem getting it to help with exploit development. I never had any issue with that with any of them, in fact, which is surprising in retrospect. Inference is so slow, and almost everything about fuzzers are meant to
20.
by nahsra 3y ago
I don't think specialized training solves any of the problems I mentioned. It doesn't increase the window size, or provide any of the types of highly specialized and optimized multi-file, multi-technique analysis, or make it any c
21.
by nahsra 3y ago
My experience is they're not good at this for most vulnerability classes, especially the those that are tough to discover by classical methods. Have you had any experience using them for this? Trivial vulnerabilities are easily discove
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by nahsra 3y ago
I said it seemed like it might be a novel addition to their practice, not to the state of the art. The question isn’t “is this possible and has anyone ever done it” - it was was “has the FBI ever used a botnet’s existing C&C patch all t
23.
by nahsra 3y ago
The FBI took control of the botnet and re-purposed it to patch the vulnerable machines. This sounds like a novel practice addition to me? I've done some limited consulting in this space in my career, and I agree that the code (and arch
24.
by nahsra 3y ago
First of all, clearly you have a ton of knowledge in this space, and I'm feeling very lucky I get to learn from your experience here. I have one more last question/challenge: I totally get that we "treat the patient" --
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by nahsra 3y ago
> https://replica.health Oh my gosh, this is the startup I considered starting last year when this issue became personal to me and I wrapped my brain around the complexity of insulin dosing. There are a lot of challenges here
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by nahsra 3y ago
I think the "no meal announcement" features are really valuable for traditionally underserved demographics who, for whatever reason, can't "get good" at managing their disease. The difference between how quickly foo
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by nahsra 3y ago
It's not clear from their site whether the Inreda product also has CGM built into it, or if it must be paired with one? Glucose-responsive insulin also seems like science fiction as this point, but would be extremely powerful tool. I&#
28.
by nahsra 3y ago
Yes, but the "patch pumps" like the Omnipod are small enough you think patients might tolerate 2 of them? Maybe they've already asked, and people wouldn't tolerate it.
29.
by nahsra 3y ago
The detectability of failure is an excellent point. Anybody who uses the hardware can confirm it's not 100%. I think your point helps me re-frame the glucagon as more of an insurance backstop for when we accidentally hit the gas a litt
30.
by nahsra 3y ago
Insulin lowers blood glucose, which of course is a vital tool. However, there appears to now be shelf-stable glucagon [1], a hormone which can be injected similarly to insulin and raises blood glucose levels. AFAIK there is only one company

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