mrosett

5 ms·

1.
by mrosett 4mo ago
It won't impact the disclosure of key business details because it doesn't reduce the level of disclosure needed in the S-1 or the 10-K.
2.
by mrosett 6mo ago
Reminds me of this classic: https://xkcd.com/1217/
3.
by mrosett 10mo ago
I'm calling BS on this one. The claimed increase in ridership is modest (18%) off a low baseline (0 service on weekends) and occurred over a long time period (pre-pandemic to today.) They also expanded service during that period, which
4.
by mrosett 11mo ago
The belief is that MH370 was depressurized which would have killed the passengers. A better example is Germanwings 9525 where the locked door allowed the first officer to crash the plane.
5.
by mrosett 1y ago
Plenty of docs making the better part of a million dollars.
6.
by mrosett 1y ago
Your assertion runs counter to the original article, which says that acquiring external practice groups raises prices.
7.
by mrosett 1y ago
These are two distinct issues. The study you linked concerns whether the hospital is owned by a nonprofit or by a private equity group. The question in this study is whether physicians work for their own practice or for the hospital directl
8.
by mrosett 1y ago
IPOs aren't what they once were. The burden of being a public company has increased (SOX and related public company costs are $5-10M/year), so companies are far more likely to stay private. That has created a positive feedback cyc
9.
by mrosett 1y ago
Checkpoint inhibitors (which are the primary driver of improved cancer treatment over the last 15 years and generate > $50B/year in sales) generally don't look very good preclinically. Even their clinical data can be hard to in
10.
by mrosett 1y ago
This is an oft-refuted trope that does harm to patients. Numerous randomized phase 3 studies show meaningful survival advantages for modern treatments.
11.
by mrosett 1y ago
This isn’t really an issue in biotech since companies don’t have any revenue until late in their lives. Ie if I’m doing discovery work for a drug candidate today, it won’t generate revenue for 7+ years. So when if I have to amortize those c
12.
by mrosett 2y ago
Does this article actually provide evidence for the headline claim?
13.
by mrosett 3y ago
Forested is not wilderness. Most forests have lots of roads, power lines running through them, etc. You're just trying to redefine a defined term.
14.
by mrosett 3y ago
I don’t think he was ever offered a plea deal
15.
by mrosett 3y ago
Western European countries are around 1 per 100,000 population per year. Seattle is 15x that rate based on those statistics. Seems bad.
16.
by mrosett 3y ago
And now I’m having the same experience
17.
by mrosett 3y ago
The comment you're responding to is incorrect. SBV was blown up by 10 year US bonds (ironically the quintessential safe investment): https://www.npr.org/2023/03/19/1164531413/bank-fail-how-gove...
18.
by mrosett 3y ago
This is entirely correct.
19.
by mrosett 3y ago
That’s the rumor.
20.
by mrosett 3y ago
That’s the freedom-to-operate side. But “Patent hell” could also be the lack of clear IP that would allow a commercializer to capture a return on developing this. Not much incentive to spend tens of millions on trials if at the of the proce
21.
by mrosett 3y ago
In the US, I would assume generally positive. The mountain west gets more sun than the northeast or northwest.
22.
by mrosett 3y ago
They have immense adaptive pressure at the cellular level. The evolutionary process plays out within each patient. Aberrant cells that don’t have some sort of evasion mechanism will be identified and destroyed by the immune system.
23.
by mrosett 3y ago
Severance is the best TV show I've seen in a long time.
24.
by mrosett 3y ago
This would only make sense if the cost-of-living indicators were actually driven by ecological impact. Instead they’re largely driven by preferences of local residents.
25.
by mrosett 3y ago
“Benevolent” dictatorship
26.
by mrosett 3y ago
The prompt matters, and GPT-4 is better than ChatGPT (apologies for missing line breaks, but the point is still clear): Prompt: A 26 year old female patient presents at the emergency room with lower right quadrant pain. What are the questi
27.
by mrosett 3y ago
Ok, apologies for a slightly irritated tone, but this touched a nerve. Of course the author is an MD who doesn’t mention the extremely high salaries paid to physicians in this country, instead acting like they’re somehow victims of high hea
28.
by mrosett 4y ago
Interesting response. Subjectively, do you THC-linked psychosis regularly?
29.
by mrosett 4y ago
It is in the non-technical sense.
30.
by mrosett 4y ago
> Daily reminder that bank runs wouldn't be a thing if we did duration matching, forbidding banks from borrowing short and lending long. If we really want to prevent bank runs, shouldn't we just forbid lending? Snark aside, tra

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