mnode

14 ms·

1.
by mnode 5mo ago
Many in the research community realised the model was wrong a long time ago. This is a great read about the reasons why: 'How not to study a disease: the story of Alzheimer’s.' by Karl Herrup.
2.
by mnode 1y ago
Base rates going up isn't fully understood but a large part is likely just changes to diagnosis. There's a recent summary of research evidence here: https://www.nature.com/articles/d41586-025-02636-1
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A mathematical model that predicts human biological age(elifesciences.org)
1 points by mnode 1y ago|1 comments
4.
by mnode 1y ago
A small number of readily measured physiological traits may be used clinically to evaluate therapeutics designed to slow aging and extend healthy life. Playing computer games associates with slower ageing.
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by mnode 1y ago
I use Elfeed within Emacs to browse feeds from https://hnrss.github.io/ . I have it fine tuned to be reasonably selective.
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by mnode 2y ago
Elfeed https://github.com/skeeto/elfeed
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Why 'open' AI systems are closed, and why this matters(nature.com)
5 points by mnode 2y ago|0 comments
8.
by mnode 2y ago
Speedball 2: Brutal Deluxe (1991, Amiga version). Awesome, future sports sim.
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Large language models can serve as a shared linguistic space for communication(doi.org)
1 points by mnode 2y ago|0 comments
10.
by mnode 2y ago
Thanks for clarifying. I didn't appreciate that it only searches abstracts. That might explain some of the missing references. Anyway, great work, will look forward to using it more.
11.
by mnode 2y ago
I tried this with a question for an area I know well. It's pretty impressive but missed some key references. I'd love to see limitations like this quantified and clearly flagged. Otherwise there's a danger that people may the
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by mnode 2y ago
Yes, that is overly cyncial. The last 10 years or so has seen big leaps in our understanding of the fundamentals of sleep mechanisms. I think there's a long way to go, but we know enough that genuinely science-based advice can help a l
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Economics scenarios for the transition to AGI [pdf](nber.org)
2 points by mnode 2y ago|0 comments
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AI used well can restore middle class jobs [pdf](nber.org)
75 points by mnode 2y ago|139 comments
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The Bill Gates Problem(nature.com)
8 points by mnode 3y ago|5 comments
16.
by mnode 3y ago
This is great! Thanks for sharing.
17.
by mnode 3y ago
In this case perverse incentives. Check out 'How not to study a disease: the story of Alzheimer’s' (by Karl Herrup) for a perspective on why this is not at all surprising. That being said, I think it would be unfair to tarnish all
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Large language models lack deep insights or a theory of mind(arxiv.org)
277 points by mnode 3y ago|261 comments
19.
by mnode 3y ago
I agree, brilliant book.
20.
by mnode 3y ago
Finally finished "Gödel, Escher, Bach" by by Douglas Hofstadter. Hugely original and entertaining, and although it's pretty old now, some ideas still very relevant to current AI debates. Also "Ringworld" by Larry Ni
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IBM Debuts Brain-Inspired Chip(spectrum.ieee.org)
2 points by mnode 3y ago|0 comments
22.
by mnode 3y ago
It does exist in nature and mechanisms of RNA interference are pretty well understood. The headline is actually incorrect here as the gene isn't altered, but instead the RNA product of the gene is suppressed. The important thing for sa
23.
by mnode 3y ago
Beautiful website. They massively over-claim on their science though. Their 'tech' is nothing special, people have been culturing and recording from neurons for years. And their claims of 'sentient' neurons in a dish sho
24.
by mnode 3y ago
Good reasons to be cautious, but a game changer if it works. This is gene silencing rather than gene editing so in principle risks to humans and the wider environment are relatively low.
25.
by mnode 3y ago
This explanation isn't consistent with my understanding. The key reasons are that SPADs have lower quantum efficiency than conventional CCDs and typical SPAD arrays have fewer pixels. Both are improving, but still not competitive for m