meew0

7 ms·

1.
by meew0 5mo ago
Metamizole is an amazing drug, I'm always grateful that I work and live in an area where it is available. But it is not a miracle drug. Metamizole-induced agranulocytosis absolutely exists, and the insidious thing is that you don'
2.
by meew0 6mo ago
Sorry if this is too specific/personal, but I've been wondering, why does the treatment timeline include antibiotics (dalbavancin)? Does dalbavancin have any suspected antitumor effects, or was it simply to treat complications of
3.
by meew0 1y ago
https://secuso.aifb.kit.edu/Team_Volkamer.php > Prof. Dr. Melanie Volkamer is a full professor at KIT in the Department of Economics and Management. She leads the SECUSO research group.
4.
by meew0 1y ago
Cysteine proteases are named after their reaction mechanism, which involves a key cysteine residue within the enzyme . It doesn't have anything to do with the amino acids in the cleaved proteins.
5.
by meew0 1y ago
The problem is that N-acetylcysteine tastes and smells awful (like farts/rotten eggs) and often causes nausea and vomiting as a side effect. The vast majority of people use acetaminophen in a safe way, and acetaminophen doesn't re
6.
by meew0 1y ago
Any EMR (electronic medical record) would probably fit this description. For example Epic, the leading one in the US: https://www.emrsystems.net/epic-ehr-software/ Or Orbis, the leading one in Europe: (there's not
7.
by meew0 1y ago
Reading about this process always makes me wonder: in a particular round, was an elector allowed to choose someone who had already been chosen in a previous round? And if yes, to what extent was this done in practice? Depending on this deta
8.
by meew0 1y ago
This was a great challenge, thanks for sharing! I do agree that the messaging could be improved a bit about what is possible and what is not. Here are my solutions, for anyone who is interested: https://gist.github.com/meew0
9.
by meew0 1y ago
There absolutely exist checklists for safe surgery as well, most famously the WHO Surgical Safety Checklist [pdf]: https://iris.who.int/bitstream/handle/10665/44186/9789241598... It's definitely wid
10.
by meew0 1y ago
Yes, in fact, most of the types of research I mentioned, where random people at hospitals do small trials on existing medications, is going to be partially government funded. But care must be taken to avoid the tulip subsidies problem [1]:
11.
by meew0 1y ago
Once drugs lose patent protection, it's difficult for them to gain approval for new indications, because drug approval procedures are extremely expensive and there's no patent holder left for whom it would make economic sense to s
12.
by meew0 2y ago
Reminds me of Scott Alexander's “GATTACA II: EPI-GATTACA”: https://slatestarcodex.com/2018/06/19/the-gattaca-trilogy/
13.
by meew0 2y ago
The screenshot feature is easily accessible in Firefox using the right-click context menu on any webpage
14.
by meew0 2y ago
I feel like you could do even better than chilies/ginger for replicating the burn. The burn from chilies feels completely different than the burn from alcohol, because ethanol is much more volatile than capsaicin. Plausibly, using a mo
15.
by meew0 2y ago
I wish there was a version of this for proportional fonts as well. I never use monospace fonts for coding anymore if I can avoid it, but I'm still in search of the “perfect” proportional coding font.
16.
by meew0 2y ago
> I’ve always liked blogging about calendrical things, but I don’t remember doing anything on the Metonic cycle before. If I had written faster, I could’ve published it on Friday the 13th. Too bad. On the other hand, you published it dur
17.
by meew0 2y ago
The “invisible symbols” are necessary to correctly represent human language. For instance, one of the most infamous Unicode control characters — the right-to-left override — is required to correctly encode mixed Latin and Hebrew text [1], w
18.
by meew0 2y ago
I do this too. It's worth noting that you don't need to host your own email server to do this. I personally use Migadu as an email host for my own domains which lets me define arbitrary wildcard redirects. I'm sure most of it
19.
by meew0 2y ago
There is a huge difference in dose between “bacteria in your mouth producing an antibiotic” and “taking an antibiotic for an infection”. Bacteria, even the normal bacteria currently present in your mouth even without taking BCS3L-1, constan
20.
by meew0 3y ago
S. mutans was named in 1924, long before the idea of genetic mutations was established. It was likely named that because it converts sugars to acid.
21.
by meew0 3y ago
Yes, for example this one: https://onyxboox.com/boox_novaairc
22.
by meew0 3y ago
Something I'm personally excited about: colour e-ink displays. There are a few decent colour e-ink tablets on the market already, for surprisingly low prices ($400-500). So far the colour reproduction and refresh rate is still somewhat
23.
by meew0 4y ago
Humans are 3D objects, but fat is not distributed equally throughout the body. Most fat is subcutaneous fat, i.e. located right below the skin. Its abundance can therefore be approximated by body surface area, which is proportional to heigh