mdomans

6 ms·

1.
by mdomans 5y ago
In general optimising Python is: * understanding that pure Python is not a language to write CPU-heavy computational code in it and was never intended as such * understanding that Python lets you write 3-4 solutions to a problem easy and 1
2.
by mdomans 5y ago
Oh boy, the IJF is going to have an epic hissy fit
3.
by mdomans 6y ago
Mostly because both JavaVM and ErlangVM are solid but Java VM is much more popular. If you're looking for a technology to run a service focused on privacy and security one of the things to consider is the amount of use and thus testing
4.
by mdomans 6y ago
Best regard to you too :)
5.
by mdomans 6y ago
> I'm not saying that every person must study these metabolic pathways in detail, but rather that the quick and simple rules and choices people make in daily life should take advantage of what is known, hopefully for a better outcom
6.
by mdomans 6y ago
> I didn't understand that the main point was "debunking the idea that insulin is what makes us fat", since I don't know anyone who believes that. Chronic poor nutrition can make you fat, sure, and rising basal insuli
7.
by mdomans 6y ago
Insulin is mostly (in humans, not rats) a hormone signalling energy availability. That's why many humans secret insulin when we smell or taste food, way before it hits GI tract. > Maintaining the insulin/glucagon cycle is impo
8.
by mdomans 6y ago
No. I can elaborate but generally it's the glucose that stimulates the insulin release (the pancreas has glucose receptors). Weight gain IS NOT driven by insulin or glucose. You can put someone on euglycemic clamp literally pumping him
9.
by mdomans 7y ago
You can't force or even ask someone to be a role model because than that's not being a role model. Much like telling someone to volunteer makes them "not a volunteer".
10.
by mdomans 8y ago
tl;dr somebody who has little idea about economy or history tries to write about economy and politics, fails miserably longer read: It's hard to consider Foucault serious basis for in-depth political analysis. I'm not a total fan
11.
by mdomans 8y ago
Cool, happy you have your stuff together :)
12.
by mdomans 8y ago
If I may, and this is a delicate topic but I often suggest talking to a psychiatrist who specialises in depression or a clinical psychologist. I know antidepressants (and visiting a psych is still a stigma somewhere, it shouldn't be) h
13.
by mdomans 8y ago
Yeah, a lot of TRT clinics are scam, especially if they employ chiropractors or naturopaths - DO STAY AWAY. Fact that those professions are allowed to give medical advice in some countries/states is actually an emerging problem because
14.
by mdomans 8y ago
It happens. There are multiple others possible problems, but I'd say that it's 20% other and 80% diet
15.
by mdomans 8y ago
Here's the best compilation of data (not mine, but by a man I incredibly respect for his insights in neuropsychopharmacology) https://www.quora.com/Can-clomiphene-citrate-trigger-depress...
16.
by mdomans 8y ago
Honestly, I have to dig through. The thing is those things are often underreported. I worked with a TRT clinic for a while, people on Clomid for fertility reasons were miserable (as in "kill me now") so that's my bias.
17.
by mdomans 8y ago
This is pure honesty and wanting to help. People who feel better on cycle usually a) in fact do need TRT and b) should consider professional counsel in regard to their psychological help. Testosterone is very potent antidepressant - if you
18.
by mdomans 8y ago
They usually have underlying psychological condition which they fail to address. Note that all the "regain" studies were done in cohorts that had either severe problems or lacked proper professional assistance (which these days yo
19.
by mdomans 8y ago
If I may chime in: trenbolone and boldenone will hit your psyche hard. Here's a short on pro bodybuilders. Most of them know jack shit about endocrine system. I'm sorry, but I work in this business. I've seen pros with IFBB p
20.
by mdomans 8y ago
The main point of Clomid are quite usual psychological side-effects, including such fun stuff as suicidal thoughts.
21.
by mdomans 8y ago
In regard to this study I'd like to point one thing. Therapeutic dose of testosterone enanthate (that can be prescribed legally) is nowhere near 600mg a week. Highest I heard of is 200mg. That will put average man above normal levels.
22.
by mdomans 8y ago
That to some degree is driven by how taboo TRT (fuelled by steroid craze of the `80s) was. In effect there were seriously hundreds of men forced to live for example on Clomid because testosterone was a no-no (compared to TRT Clomid is like
23.
by mdomans 8y ago
Something I think should pointed out in the article is that the author tries to understand testosterone (I don't know why, since it's effects through maturation are actually quite a bit studied, there are medical textbooks on it)
24.
by mdomans 8y ago
It'd be a nice theory but we actually know that as men get their testosterone levels lower they get to be at higher and higher risk of certain diseases. For example, testosterone is often cited as carrying risk of CVD and for many year
25.
by mdomans 9y ago
Probably, not so much. The amounts of ingredients and composition of ingredients in energy drinks are just stupid. I see now a trend of "health" drinks that actually seem sensible, though a bit more pricey. Like magnesium, ginseng
26.
by mdomans 9y ago
Well, yeah. This is the level of oppression Soviet Russia was. The horrors of Nazi camps are often discussed - not many people discuss Russian camps on Siberia.
27.
by mdomans 9y ago
This isn't really huge news, technically speaking. Any anti-inflammatory drug will have negative net impact on your body function. For a while we know now that NSAIDs alter ROS levels in response to injury and in fact any normal proces
28.
by mdomans 9y ago
And an extra note when someone says "it's hard to implement ... without locks and so". Look at Firefox. I dumped it's bushy tail around 7 years ago when switching to the apple-scented world for good. I came crawling back
29.
by mdomans 9y ago
Also as a pinch-of-a-salt in the whole sugary environment of HN where every new feature is cool by definition. For example, what are the shortcomings of Kafka compared to Redis Streams?
30.
by mdomans 9y ago
It was meant as a joke. Alas, I have been more than once bitten by poorly implemented GIL and in my personal experience any GIL is problematic in a high-throughput environment. It simplifies the problem of implementation of environment or A

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