mcbain

7 ms·

1.
20× the CI traffic without getting slower: How we rebuilt Git serving at Datadog(datadoghq.com)
4 points by mcbain 28d ago|0 comments
2.
by mcbain 6mo ago
You might enjoy the matrix of regional sizes and names on Wikipedia: https://en.wikipedia.org/wiki/Beer_in_Australia#Beer_glasses No, us locals don't know them all either!
3.
by mcbain 6mo ago
https://www.avherald.com/h?article=536bb98e > Captain and first officer are reported to have died in the accident, two fire fighters on board of the truck received serious injuries, 13 passengers received injuries.
4.
Air Canada CRJ collides with fire fighting truck on landing in New York(flightradar24.com)
7 points by mcbain 6mo ago|1 comments
5.
Molecule in Python blood could pave way for new obesity drugs(theguardian.com)
4 points by mcbain 6mo ago|1 comments
6.
by mcbain 7mo ago
The former. It doesn't quite roll off the tongue, but with my (Australian) accent the difference is minor.
7.
by mcbain 7mo ago
Yes, with MRI brain too. I was on 4/year, but that number is reducing as time goes on without recurrence.
8.
by mcbain 7mo ago
I have multiple scans a year. "Scanxiety" is real.
9.
by mcbain 7mo ago
Spot on. And dealing with false positives sucks. One caveat is that regular PET isn't so good in the brain - there is so much metabolic activity that everything glows. So I get an MRI Brain to go with my regular full body PET/CT (
10.
by mcbain 9mo ago
Previously: https://news.ycombinator.com/item?id=45514378
11.
by mcbain 10mo ago
Linde was definitely around as a distinct brand in Australia before they bought BOC in 2006, but since then as you said, they now just trade as BOC.
12.
by mcbain 11mo ago
When have they ever claimed that?
13.
by mcbain 1y ago
As others pointed out, these are stage I trials and these are patients that have had other treatments already. In particular the melanoma patients had already had other immunotherapy - which is known to work for 50+% of cases - so this coul
14.
by mcbain 1y ago
The testing here is not just that it is safe on skin, but the SPF test itself is done by slathering it on humans and exposing them to light to determine a rating.
15.
by mcbain 1y ago
Also the club scenes, with a bunch of regulars from Hellfire/Black Market, on Regent St. (Now a cafe supply store.)
16.
by mcbain 1y ago
Sadly Richard has now had recurrence. There is still hope for this treatment for others, and it likely extended his life, but it isn't happily ever after this time.
17.
Why I no longer have an old-school cert on my HTTPS site(rachelbythebay.com)
409 points by mcbain 1y ago|420 comments
18.
by mcbain 2y ago
https://www.nature.com/articles/s41591-025-03512-1 Ipi/nivo/relatlimab and then a peptide vaccine that they haven't written up yet.
19.
by mcbain 2y ago
No chemo. The entire idea of this regime is to hit the tumour with immuno to get the reaction. They want lots of tumour cells and for it to be "treatment naive" - Richard hadn't even had corticosteroids, which dampens immune.
20.
by mcbain 2y ago
https://youtu.be/Y5K9HBiJpuk I think Petter's (Mentour Pilot) delve into it is quite good - there's a lot of detail I hadn't known.
21.
by mcbain 2y ago
It's easy for (say) AWS to terminate your EC2 instances. Do they also delete your DB backups? Delete your S3 buckets? All of these incur costs. How hard a cap do you want?
22.
by mcbain 2y ago
One big trial still going: https://clinicaltrials.gov/study/NCT03739931
23.
by mcbain 2y ago
There's a bunch of different immuno types for melanoma (and other cancers). That one is a combo of nivolumab (aka Opdivo) and relatlimab. Nivo is used a lot for melanoma, also commonly in combo with ipi (ipilimumab, yervoy). Pembro (ke
24.
The Titan Submersible Disaster. The Inside Story Is More Disturbing(wired.com)
125 points by mcbain 2y ago|115 comments
25.
by mcbain 2y ago
It does launch an instance and take a snapshot but what's happening is the sysprep and OOBE stuff that can take 10 mins or so (you can find it in the console and startup logs). That's a lot more overheard than just hydrating an EB
26.
by mcbain 2y ago
This is seeing great results but unless I'm mistaken, this started stage III in July 2023: https://classic.clinicaltrials.gov/ct2/show/NCT05933577
27.
by mcbain 2y ago
They are https://en.m.wikipedia.org/wiki/PD-1_and_PD-L1_inhibitors The hint is the -mab naming.
28.
by mcbain 2y ago
I get an MRI Brain every three months. I usually opt out of the piped music - mostly because it's either a bad choice by the radiology techs or tuned to a generically awful radio station - but the headphones lock into the head cradle s
29.
by mcbain 3y ago
The title here currently drops "Western" from the linked article and the start of the airport name - importantly this is the yet to be completed WSI not the existing SYD.
30.
NSW Digital Licence core is a 1980s green screen Solaris rig(themandarin.com.au)
1 points by mcbain 3y ago|0 comments

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