maxall4

7 ms·

1.
Isaac Asimov Asks, "How Do People Get New Ideas?"(technologyreview.com)
4 points by maxall4 22h ago|1 comments
2.
by maxall4 8d ago
One of the most egregious cases of this, in my opinion, is only publishing metrics that cover part of the confusion matrix. “The false-negative rate? That could not possibly matter for a variant effect prediction model; why would we include
3.
by maxall4 13d ago
I really want to like Julia. It has a nice type system, a good ecosystem, reasonable syntax, and it’s far faster than Python. But there are several issues with its DX that prevent me from using it: the most severe of which being the complet
4.
by maxall4 13d ago
The benefit is probably from the removal of fat, not a direct antibacterial/antiviral effect. Fat plays a complex immunoregulatory role in human physiology: it down-regulates some pathways, while up-regulating others (notoriously, the
5.
by maxall4 13d ago
The official ARC-AGI 3 score—-without OpenAI’s custom harness—-can be found here: https://arcprize.org/leaderboard . Astra scores 62.7% at max reasoning for the low-low price of 26,000 dollars.
6.
by maxall4 13d ago
“I declare bankruptcy!” - Michael Scott
7.
A Cop's Case for Flock(worksinprogress.co)
2 points by maxall4 18d ago|0 comments
8.
The Implausibility of Intelligence Explosion (2017)(medium.com)
3 points by maxall4 18d ago|0 comments
9.
The University in the AI Era(four.htmx.org)
1 points by maxall4 19d ago|0 comments
10.
by maxall4 21d ago
I’m no expert, but I don’t believe that “high-assay low-enriched uranium” is the sort you can use in nuclear weapons, per it being “low-enriched”. According to the DOE, HALEU only goes up to 20% enrichment [0]. Nuclear weapons, it seems, ne
11.
Photon Gas(en.wikipedia.org)
2 points by maxall4 24d ago|0 comments
12.
A New Kind of Science by Stephen Wolfram: Monster Raving Egomania(bactra.org)
21 points by maxall4 25d ago|5 comments
13.
Science investigation suggests serious problems in Alzheimer's work(science.org)
2 points by maxall4 29d ago|0 comments
14.
by maxall4 1mo ago
Status page reports as down: https://status.claude.com/
15.
A New Alzheimer's Therapy – Or Is It?(science.org)
4 points by maxall4 1mo ago|2 comments
16.
FNIP1 variants are associated with favourable metabolism in 1M humans(nature.com)
2 points by maxall4 1mo ago|0 comments
17.
by maxall4 1mo ago
I agree that purchases on e-commerce sites are virtually never this fast; but I have used some extremely fast physical payment terminals (e.g., Square): sometimes it seems like the transaction is sub 300ms, which I find very impressive give
18.
Engineering a plant-derived nanofoundry to power mammalian cells(cell.com)
2 points by maxall4 2mo ago|0 comments
19.
by maxall4 2mo ago
Likewise, I have started doing Project Euler problems for fun, and to further my mathematics education.
20.
Anthropic should learn from those cotton-picking socialists(asteriskmag.com)
17 points by maxall4 2mo ago|1 comments
21.
Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer(nejm.org)
2 points by maxall4 2mo ago|1 comments
22.
Rising stars of mathematics awarded prestigious 2026 Fields Medal(nature.com)
4 points by maxall4 2mo ago|0 comments
23.
by maxall4 2mo ago
I'm honestly quite shocked that the physicians/scientists involved would choose to use an AAV for a brain-targeted gene therapy. There is just so much data demonstrating that these vectors are quite immunoreactive: most of the app
24.
Thoughts on the "Netflix Analogy"(science.org)
5 points by maxall4 2mo ago|0 comments
25.
by maxall4 2mo ago
I very much enjoyed Grok 4.5's rendition of the Mona Lisa as Elon Musk with tentacles.
26.
by maxall4 3mo ago
Especially an MRI which is a 3D medium —something current LLMs are very bad at.
27.
by maxall4 3mo ago
Or, alternatively, it may suggest that the NSA’s classified systems are not very secure, which seems at least as possible: they may rely on requiring physical access to these systems to even attempt to penetrate them.
28.
by maxall4 3mo ago
It doesn’t seem like it? Unless I am misunderstanding these Nasdaq insider trading reports: https://www.nasdaq.com/market-activity/stocks/cbrs/insider-a...
29.
by maxall4 3mo ago
This is rather reminiscent of the Bogdanov affair: https://en.wikipedia.org/wiki/Bogdanov_affair
30.
by maxall4 3mo ago
> We have reviewed the report and validated that the level of capability displayed there is widely available from other models (including OpenAI’s GPT-5.5), and is used every day by the defenders who keep systems safe. We will share mor

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