lekanwang

5 ms·

1.
by lekanwang 2y ago
As an investor in healthcare AI companies, I actually completely agree that there's a lot of bad implementations of AI in healthcare settings, and what practitioners call "alarm fatigue" as well as the feeling of loss of agen
2.
by lekanwang 2y ago
Pediatric allergy and atopic diseases in general is a mess an only slowly getting better. There's strong correlation between early eczema and food allergies, and now mild but convincing evidence it could even be causal. That eczema (an
3.
by lekanwang 2y ago
Freestyle rap should be the modern equivalent. Can judge on things like lyricism, flow/delivery, concept/cohesiveness, etc.
4.
by lekanwang 2y ago
As a healthcare tech investor, I do see a lot of startups selling potentially dangerous AI systems into the healthcare system. That said, there are also a good number of companies that are implementing systems thoughtfully to address a numb
5.
by lekanwang 3y ago
Metagenomic sequencing: The field exploded after technologies and techniques were developed for using next-gen sequencing to characterize entire populations/communities of living things, first with 16S rRNA sequences, then with full ge
6.
by lekanwang 3y ago
Yep, you're right. Only meant to associate them in terms of why they're valued land, but yes, they're in separate riparian zones. Central valley is Sacramento/San Joaquin river delta.
7.
by lekanwang 3y ago
The unfortunate thing is that large stretches of California desert (and much of the Central Valley to the north) used to be lake bottoms and have incredibly rich and fertile soils. Between that and a long growing season that's nearly c
8.
by lekanwang 3y ago
I like the Singaporean model of benchmarking high-ranking government salaries to a percent of the pay of top earners in the country ( https://www.dollarsandsense.sg/heres-much-singapores-preside... , https://www.ps
9.
by lekanwang 4y ago
Broadening out, this reminds me of one of the most eye-opening classes I've ever taken (and it was back in high-school!) -- Comparative Government/Politics: https://apcentral.collegeboard.org/media/pdf/ap
10.
by lekanwang 4y ago
Had a similar experience with GCP -- wanted to run an experiment in AWS, Azure, and GCP side-by-side. AWS and Azure were set up within a day. GCP required hitting up support to "turn on the feature," then a salesperson called to t
11.
by lekanwang 5y ago
I'm finding with the teams I'm working with that the junior employees are the ones most impacted by not working from an office, but they often don't realize what they're missing -- the less formal forms of mentorship, st
12.
by lekanwang 5y ago
You should -- protease inhibitors inhibit replication, but existing viruses should be more than enough to generate a durable response in most individuals.
13.
by lekanwang 5y ago
Yeah, as parent mentioned in another reply below, ritonavir is an antiviral, but has no effect on SARS-CoV-2 ( https://pubmed.ncbi.nlm.nih.gov/34048671/ ). Ritonavir is just used to inhibit CYP and therefore reducing cle
14.
by lekanwang 5y ago
ACLU, Cato, EFF, and EPIC have all shown real success in legislative efforts and in court.
15.
by lekanwang 5y ago
This is a decent state-by-state overview of the enforceability of non-competes: https://www.wonder.legal/us/guide/what-is-the-enforceability...
16.
by lekanwang 6y ago
Reminds me of when a honeybee swarm occupied the parking lot behind our building and eventually mostly settled on a bike rack (this also happens to be the building of the downtown Palo Alto Philz). As a beekeeper, I was so excited that I em
17.
by lekanwang 6y ago
^ Yeah that's directionally accurate. The AMA is one of the two funders of LCME, the accrediting agency of medical schools for MDs (outside of the med school trade association itself). While they do not run medical schools, they have e
18.
by lekanwang 6y ago
The AMA chooses who can be a doctor, who can train doctors, who can practice any kind of medicine, has extremely strong pricing power over the entire healthcare system via the RUC ( https://en.wikipedia.org/wiki/Specialt
19.
by lekanwang 6y ago
I was fascinated with the history of the Sami when I visited Karasjok in the dead of winter, and spoke to a few who still tried to keep a somewhat traditional lifestyle. It did feel like it was a fight against time to keep those nomadic her
20.
by lekanwang 6y ago
You can't go faster than the speed of light in a vacuum. But, you can definitely go faster than light in a medium. Speed of light in water, for example, is around 0.75c.
21.
by lekanwang 6y ago
I think you are perhaps conflating the public health definition of surveillance with what HN usually thinks of as "surveillance." (see https://en.wikipedia.org/wiki/Public_health_surveillance ) In the US, if y
22.
by lekanwang 6y ago
The WHO usually isn't in the business of sponsoring trials. The development of a single master protocol takes time, especially for one as large as this, and pulling one together within just a few weeks is already quite incredible, give
23.
by lekanwang 7y ago
I've worked on data related to healthcare and security (and sometimes both) for quite a while now, and I think there are a couple of general contextual themes, where, if present, means that you have to be extremely careful about applyi
24.
by lekanwang 7y ago
I think you may be referring to this publication: https://energyanalysis.lbl.gov/publications/co2-indoor-pollu...
25.
by lekanwang 7y ago
Having worked closely with FDA, I've been very impressed by the people there and how thoughtful they are despite the pressure they're under and the almost complete lack of good software tooling due to the sensitivity, regulatory r
26.
by lekanwang 8y ago
Yes, this is a very good point -- you're on the clock as soon as you file your patent, so sponsors have an incredibly strong incentive to take risks with trial design and use surrogate endpoints rather than direct endpoints for the pri
27.
by lekanwang 8y ago
You'll need more patients, which is expensive. But yes, you're actually right -- sponsors do run stratified phase 3 trials where subsets of patients are measured independently per pre-approved statistical analysis plan. The rub is
28.
by lekanwang 9y ago
I think there's false premise here that cancer has a single magic cure and we just need to focus on researching that instead of this expensive "personalized medicine." Cancer is a complex beast, and what we term cancer is rea
29.
by lekanwang 11y ago
A lecturer at Stanford CS (Keith Schwarz) also has a good collection of various implementations of interesting algorithms: http://www.keithschwarz.com/interesting/
30.
by lekanwang 12y ago
Cute idea. But as a beekeeper in the Bay Area, I have to agree with @tehchromic--there's some tricky stuff to consider to make this work: - How will they prevent the bees from covering the internal mechanism with wax? Bees often cover

More ›