jryb

7 ms·

1.
I'm sorry, you're not going to die from an AI-engineered supervirus(blog.genesmindsmachines.com)
86 points by jryb 7d ago|126 comments
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by jryb 7d ago
https://blog.genesmindsmachines.com/p/im-sorry-youre-not-goi...
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by jryb 2mo ago
Local cops/AG persecuting groups they don’t like
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by jryb 3mo ago
When you’re deciding which antibodies to buy you’ll look at these figures to get a sense of their quality. Antibodies aren’t perfect and might bind proteins unrelated to the one you want to study. Depending on your application, some off-tar
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by jryb 3mo ago
Was there not enough interest from institutional investors?
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by jryb 4mo ago
I can see using them as a source of randomness for an aleatoric composition: https://en.wikipedia.org/wiki/Aleatoric_music
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by jryb 4mo ago
There’s nothing to be reminded of. English has a word to describe North and South America together (“the Americas”). Other languages have different words for the same concept. It’s like reminding someone they shouldn’t say “bicycle” but sho
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by jryb 4mo ago
This could easily be sleep apnea
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by jryb 5mo ago
Just wanted to say that I share any frustration you may feel at every reply to your comment completely missing the point
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by jryb 5mo ago
I’d be surprised if they’re running at less than 100% capacity after this. It’s just too useful to too many people for whom an $80/month increase is immaterial (I speculate)
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by jryb 5mo ago
I think it would be helpful to reframe this as a statistical problem, and not as an issue with units. Estimating some measure of central tendency and variance (mean and 95% CI maybe? I'm not familiar with time series statistics) would
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The AI Rewrite Dilemma(lh3.github.io)
2 points by jryb 5mo ago|0 comments
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by jryb 5mo ago
You’re conflating the colloquial meaning of “fitness” with the technical definition. It’s unfortunately overloaded.
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by jryb 6mo ago
You only get ~30 seconds of zero G. How would that work?
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by jryb 6mo ago
It’s been well known for as long time, the news here is the specific biological mechanism, which may open up new areas of research.
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by jryb 6mo ago
This is a difference without distinction.
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by jryb 7mo ago
Regardless, we're talking about a distribution of abilities, and the number of people who can't drive safely is going to increase dramatically in the near future. The point of this article wasn't to judge all boomers.
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by jryb 7mo ago
I work in a field that has a strong glass ceiling, and the only way through is with a PhD (some employers are starting to recognize that, with several years of experience, people with a bachelor's or master's degree can attain the
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by jryb 7mo ago
You don't need to synthesize an entire bacterial genome from scratch to do this. You can just insert them one at a time into existing bacteria. Or just give them plasmids. Anyway, the ability to achieve the outcome you're describi
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by jryb 7mo ago
Paper: https://www.nature.com/articles/s41586-025-10006-0
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by jryb 8mo ago
Sure, but there apparently wasn't enough of a dialog either. With a textbook, you're confronted with facts and explanations that you didn't ask about, or even knew to ask about. Don't get me wrong - my original recommend
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by jryb 8mo ago
LLMs may be enabling, but OP explicitly stated "I wanted to dig deeper into the subject, but not by reading a boring textbook", which, of course, would have eliminated the issues in this tool, or at least made it clear to them tha
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by jryb 8mo ago
This is so riddled with inaccuracies that I can spot them immediately despite not being a phage biologist. For example, the PhiX image has a DNA with about 20 base pairs - wildly not to scale. M13 is also wildly scaled, and it clearly has a
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by jryb 8mo ago
Not solved at all. Certainly AF is very useful but what it outputs is a fundamentally a prediction with important limitations. There’s plenty of utility in physical modeling.
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by jryb 8mo ago
This post might get the record for people responding to the title without reading the article. Jeez people, it takes five seconds to discover that it subverts expectations.
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by jryb 8mo ago
Years ago I worked at an insurance company where the whole job was doing this - essentially reading through long PDFs with mostly unrelated information and extracting 3-4 numbers of interest. It paid terrible and few people who worked there
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by jryb 8mo ago
But in the proposed scenario, there wouldn’t be any technical hurdles or effort required by the phone’s owner - you could have this be a service offered by businesses. Maybe even the place that sells the phone would pre-jailbreak it for you
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by jryb 8mo ago
To answer your first question, I work on cancer therapeutics. But maybe some perspective from the other end of the “meaningful work” continuum would be helpful in answering the real question. If your company creates any real utility to a pe
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by jryb 9mo ago
Doors no, couch yes (if it fits). I wouldn’t get one unless you see value in having 80% of your home vacuumed once a day. For me that’s still a huge improvement and spending a few minutes spot vacuuming every two weeks or so is all I need t
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by jryb 10mo ago
No one will touch this guy with a ten foot pole. Nothing he did technically was novel - it was just that everyone who had the skills to edit an embryo was unwilling and uninterested in doing so. Having him as part of your organization basic

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