jlafon

7 ms·

1.
by jlafon 5y ago
Many have commented here on the computational challenges of enumerating, storing, and searching very large virtual libraries. While molecules can be represented and stored as strings, that's an oversimplification of the problem (from a
2.
by jlafon 10y ago
OpenEye Scientific | Santa Fe, NM | Onsite/Fulltime | http://www.eyesopen.com/careers OpenEye Scientific Software provides software to the Pharmaceutical Industry for molecular modeling and cheminformatics. It has done
3.
by jlafon 10y ago
First of all, I'm not defending what is obviously predatory. However, there is more involved then what you might think at first glance. Right or wrong, correctional facilities have reasons to discourage phone calls (context: I put myse
4.
Cycle Computing gets patent for detecting faults in cloud infrastructure(patft.uspto.gov)
1 points by jlafon 11y ago|0 comments
5.
by jlafon 11y ago
OpenEye Scientific Software (Santa Fe, New Mexico) - various positions: http://www.eyesopen.com/careers
6.
Show HN: Parallel file utilities for petabyte scale file systems(github.com)
3 points by jlafon 11y ago|0 comments
7.
by jlafon 11y ago
Nice work. I implemented something very similar last year: https://github.com/jlafon/pynamodb .
8.
Making Python 3 more attractive(lwn.net)
10 points by jlafon 11y ago|1 comments
9.
by jlafon 12y ago
That makes sense. I had only seen the Memcache & Redis datastores being used (and both being comparable to DynamoDB).
10.
by jlafon 12y ago
It's interesting that Netflix decided to write this rather than using Amazon's own DynamoDB. I wonder specifically if DynamoDB was too expensive (as I have found), or was there some other reason?
11.
by jlafon 12y ago
Author of the paper here. The file operations are distributed strictly without links, otherwise we could make no guarantees that work wouldn't be duplicated, or even that the algorithm would terminate. We were lucky in that because the
12.
by jlafon 12y ago
What I meant is that getting the toolbar to show up when you aren't serving from localhost isn't as trivial as setting DEBUG=True. It requires other settings ( https://github.com/django-debug-toolbar/django-deb
13.
by jlafon 12y ago
I end up using Django Rest Framework ( http://www.django-rest-framework.org/ ) generated UIs along with the debug toolbar, and then disabling the generated UIs when I'm done profiling.
14.
by jlafon 12y ago
For those interested, here are a couple of differences between this and django-debug-toolbar (an excellent, widely used utility that also provides SQL inspection). 1. django-debug-toolbar can be difficult to enable if you aren't servin
15.
by jlafon 12y ago
I'm trying to understand this too. This is only a problem if the OAuth provider (Google, Twitter, etc) does not validate the URL that the client is trying to redirect the user to after the user has authorized the app, correct?
16.
by jlafon 12y ago
If you did a line for line transliteration, did you use any of Go's concurrency features such goroutines or channels? I ask because I find that when I translate a program from Python to Go that it's beneficial to structure the pro
17.
by jlafon 12y ago
Well done. All of my questions were answered by browsing the site. +1 for using SSL everywhere.
18.
by jlafon 12y ago
Out of curiosity, why did you choose Ember? For context, my team is evaluating Angular vs. Ember. Thanks.
19.
by jlafon 13y ago
Can someone explain the downvotes?
20.
by jlafon 13y ago
Front end web developer, OpenEye Scientific Software - Santa Fe, NM Email hr@eyesopen.com for details. About OpenEye Scientific Software, Inc: OpenEye Scientific Software provides software to the pharmaceuticals industry for molecular model
21.
by jlafon 13y ago
The most interesting part to me is that there is no database. It had never occurred to me to use Django without one.
22.
by jlafon 13y ago
How can this be? Perhaps, their sample is biased? It would really be sad if 25% of Americans really have this misconception - not to mention the similarly high percentages for other countries.
23.
by jlafon 13y ago
Java has many great features, but I find it to be too tedious for me to experiment. For example: want to read a file into a string? The Python version is open(name).read(), and I've never seen a Java equivalent be that concise.
24.
by jlafon 13y ago
This looks pretty cool! I like the story flow. You might want to include some links that explain what the keys are, what PGP is, etc - because not everyone who lands on your site will know.
25.
by jlafon 13y ago
This looks really powerful, and I'm glad you offer student pricing.
26.
by jlafon 13y ago
Yeah, it's probably a developer focused mindset, but I'm a developer. Without a test suite, it makes it very difficult for anyone to contribute, because there isn't a clear way to tell if they broke something. How do you deci
27.
by jlafon 13y ago
I wasn't counting the default django 1 + 1 test, but I did find one actual test. It's obvious that a lot of work was put into this, and I think it has potential. My suggestion to the creators is to start with tests from the beginn
28.
by jlafon 13y ago
This looks interesting, but I can't take it seriously. From what I can tell, you haven't written any tests at all.
29.
by jlafon 13y ago
Or, I could send an email with my signature line, which includes most of that information. Am I missing something?
30.
by jlafon 13y ago
What is the advantage of adding braces to Python? I find Python's indentation based syntax to be very readable, very close to pseudo code.

More ›