jashephe

5 ms·

1.
by jashephe 6mo ago
It sounds like you want a dictation mic. Philips’s SpeechMike and OM System’s (formerly Olympus) RecMic are big in the healthcare space. My SpeechMike is wireless with a USB dongle and has something akin to a trackpoint for mouse movement,
2.
by jashephe 1y ago
The periodic table poster under "High binding problems" is billed as evidence of model limitations, but I wonder if it just suggests that 4o is a fan of "Look Around You".
3.
by jashephe 3y ago
I'm a little disappointed that their linked preprint doesn't appear to include any molecular biology; i.e. they don't actually try to synthesize any of their predicted sequences and test function. It wouldn't be an outra
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by jashephe 3y ago
A tangent: does anyone have recommendations for a library for easy Swift-Rust interop? This is a cool tool, but I’d much rather make a GUI natively with e.g. SwiftUI and then call out to Rust for business logic. The previous times I’ve look
5.
by jashephe 4y ago
All sorts of offtopic prompts are unsurprisingly generating nonsensical answers, but even prompting with "lecture notes on clathrin-mediated endocytosis" yielded: "In the case of clathrin-mediated endocytosis, it is a process
6.
by jashephe 4y ago
Global models of gene expression for an entire cell are fairly distant at this point, but there is quite a bit of work into modeling transcriptional activity from sequence. If you're interested in reading more, a relevant technology to
7.
by jashephe 5y ago
I'm confused. Where does this say the vaccine is mRNA? The Valneva VLA15 website explicitly states "VLA15 is a multivalent recombinant protein vaccine" [1], and the linked press release calls it a "investigational multiv
8.
by jashephe 5y ago
Not sure why a direct quote from the article is getting so heavily downvoted. Maybe there’s something here, but if the variants were in the published paper, it doesn’t really matter if the raw sequences were yanked off of the SRA.
9.
by jashephe 5y ago
Taum Sauk is unusual in that the dam fully surrounds the upper reservoir (i.e. the lake was made from scratch), although certainly all types of dam can fail.
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by jashephe 5y ago
I'd be quite interested to see if there's any correlation between Valisure's measurements and time elapsed since manufacture for each lot.
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by jashephe 6y ago
Isn't pumped storage hydro kind of that "silver bullet"? At least in places with the right geography?
12.
by jashephe 6y ago
Indeed. Maybe someone with more expertise can chime in — it's not clear to me if getting a vaccine with the chimp adenovirus backbone would preclude the possibility of getting another vaccine based on that backbone in the future (becau
13.
by jashephe 6y ago
Based on this NYT article [1], some logistics companies planning to store and transport the vaccine are using freezers from Stirling Ultracold. It may just be a curiosity, but their freezers (as the name would suggest) use bona fide Stirlin
14.
by jashephe 6y ago
It’s always surprising to me to see an article like this that’s vaguely about a person, without seemingly any attempts to reach that person for comment. I’ve filed issued on a few of Michael’s repositories since he left Apple, and he was ex
15.
by jashephe 6y ago
While "Heroes of CRISPR" is a fairly detailed history of the whole affair, it's always worth noting that it was written by Eric Lander, the director of an institute with a strong vested financial interest in having the story
16.
by jashephe 6y ago
Indeed. In Chadwick Boseman’s case, the onset was at _such_ a young age that it suggests (total speculation) he might have had a hereditary cancer syndrome or some other familial risk factor. More widespread genetic testing may help people
17.
by jashephe 6y ago
Just to clarify — the vaccine uses as its backbone a type of adenovirus that typically infects chimpanzees, modified by the addition of pieces from SARS-CoV-2, but the experiments testing efficacy are performed in mice (specifically, a type
18.
by jashephe 6y ago
The above is a good example of how results can be "wrong" in theory papers, but I work in an experimental field of research and at least in my world, having a paper present results that turn out to be wrong isn't really all t
19.
by jashephe 6y ago
This calls to mind the ever-relevant “Science: The Endless Frontier” [1] by Vannevar Bush, who more or less oversaw the entire American federal research enterprise during and post-WWII. He famously said that the best thing you can do for sc
20.
by jashephe 7y ago
Oh, absolutely. I guess I was wondering if accusations alone would serve to substantially inconvenience or embitter individual scientists, or decrease public trust in academic research and academicians in general. Not trying to suggest that
21.
by jashephe 7y ago
The conspiracy theorist in me can't help but wonder if "leaking" forged documents of this nature could be an effective way for China or another foreign government to sabotage the leaders of the American research enterprise. O
22.
Whistleblower Reveals Failings at UNC Pediatric Heart Surgery Department(nytimes.com)
1 points by jashephe 7y ago|0 comments
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by jashephe 7y ago
Some folks have raised plenty of practical/medicolegal reasons, but it's also worth noting that patients are often not comfortable being told that they have an "anomaly" that their doc is going to sit back and do nothin
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by jashephe 7y ago
Some of the comments here don't touch on the practical limitations of this, but here's one — I'm at a 1400+ bed top-10 US academic medical center, and even our outpatient MRI machines book patients until near-midnight becau
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by jashephe 7y ago
(for context) https://twitter.com/realDonaldTrump/status/11178449872934871...
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by jashephe 8y ago
Tangentially, it's interesting to see how Samsung's reveal video (at the top of the article) [1] is so uncannily similar to what Microsoft came up with a few years ago for the Surface Studio [2], right down to the music selection.
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by jashephe 9y ago
For lack of a rebuttal to the FDA dissolution comment, which I'm sure others are more qualified to respond to, I wanted to address the efficacy/safety remark: A growing number of people have voiced objections to the burdens of the
28.
by jashephe 9y ago
The fact is, unfortunately, that Nanopore sequencing (and also, from what I’ve read, PacBio) has a dramatically higher error rate than Illumina sequencing-by-synthesis. In the near future, anyway, I would expect to see inaccurate PacBio&#x2
29.
by jashephe 10y ago
Right, but none of the incidents on that list involved a nuclear missile silo. I read the author's sentence as "It would have been impossible ( for Morris or other silo crew members ) to start World War Three by accident."
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by jashephe 10y ago
It's important to note that aging is not so much a mechanism to protect against cancer as it is a method to avoid cancer (that is, by dying before cancer develops).

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