iskander

7 ms·

1.
How to Design a Cancer Vaccine(owlposting.com)
4 points by iskander 2mo ago|0 comments
2.
by iskander 2y ago
Lots of practical but low impact suggestions in this thread. I think the only real answers involve large scale decoupling from the rapidly changing social norms. Can you cobble together a social group that will go Luddite with you? If not,
3.
by iskander 2y ago
I think unpopular to mention here but John Ioannidis did a really weird turn in his career and published some atrociously non-rigorous Covid research that falls squarely in the cross-hairs of "why...research findings are false".
4.
by iskander 2y ago
>we don't try to attack the actual cause It's cars and large houses peripherally connected to amenities by car-only infrastructure. People love this lifestyle and will fight you very energetically if you try to do anything to n
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by iskander 2y ago
What is Invidious? An alternative front-end to Google-hosted video content?
6.
by iskander 3y ago
#1 on ASPCA's list of common toxicoses in cats: https://www.aspcapro.org/sites/default/files/zl-vetm0606_339... Study of 286 cat/permethrin cases in London: https://journals.sagepub.com&#
7.
by iskander 3y ago
Related: Verifiable Delay Function https://link.springer.com/article/10.1007/s00145-020-09364-x
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by iskander 3y ago
Only clue in the source:
9.
by iskander 3y ago
I love the simple but elegant formatting of this blog. cgadski: what did you use to make it?
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by iskander 3y ago
Exceptions so far are Novo Nordisk and CostCo. Not sure if there are many others at scale.
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by iskander 3y ago
Not that anyone is offering $192B but I also suspect existing doctors and the AMA might actively oppose this. Debt-free MDs would probably create downward pressure on salaries.
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by iskander 3y ago
My dog seems to know least the names of 6 family members, 4 friends, and names of ~6-7 other dogs (in that she can go to those individuals on command). She also knows: cat, dog, cow, horse, friend, hello, "dai lapu" (Russian for g
13.
by iskander 3y ago
Moved to the US as a kid (by way of Estonia and then Italy), went to a year of Russian language "transitional" school here. So don't have any insight on the Ukrainian school experience.
14.
by iskander 3y ago
I was born in Kiev and spoke Russian at home. Can barely understand Ukrainian unless it's spoken slowly by a native Russian speaker. I can get the gist of what Zelensky is saying in an interview but can pretty much never understand nat
15.
by iskander 3y ago
I expected the core of the algorithm to be a parallel prefix scan though (isn't that the point of Mamba?): for i in range(l): x = deltaA[:, :, i] \* x + deltaB_u[:, :, i] y = einsum(x, C[:, i, :], 'b
16.
by iskander 3y ago
Keras started out great but grew clumsily, making custom use-cases cumbersome and error prone and also became inextricably linked with TensorFlow (which was a big headache compared with PyTorch). It seems like this rewrite cleans up the mea
17.
by iskander 3y ago
Like, huge tangible improvements. You can do general purpose programming in all kinds of DSLs and Rust libraries that compiles down to big-but-practical arithmetic circuits and then generate proofs that y=f(x) without revealing x for arbitr
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by iskander 3y ago
Can you still!? It's so incredibly traceable these days and every iteration of Silk Road gets busted, no?
19.
by iskander 3y ago
Merkle trees, yes! That was just an example of a technique that can be well hidden vs in the user's face. Newer techniques like Verkle trees, SNARKs, STARKs, &c are.... well, new.
20.
by iskander 3y ago
I think the initial impractical prototypes for the core techniques were in the literature for a while but there's really no comparison between eg interactive ZK protocols and the succinct non-interactive proofs used by the cryptocurren
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by iskander 3y ago
It would be a shame if this keeps happening, like: (2013) Bitcoin and its clones failed at all their stated purposes, (2017) the ICO craze left nothing of value, (2021) the DeFi/NFT bubble also left nothing but rubble. This stuff is ze
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by iskander 3y ago
I think you'll see people picking those techniques and using them in a hidden-from-the-user way (like how git and BlueSky use Merkle trees)
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by iskander 3y ago
I gave the "industry" a pretty thorough deep dive; I learned Solidity, wrote a bunch of smart contracts, tried a lot of DeFi, and listened to ~100 episodes of the Zero Knowledge podcast. My impression on the other end of it is tha
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by iskander 3y ago
Scott's political ontology seems intrinsically limited to white middle class. It doesn't really make sense in poorer parts of America and really falls apart once you start trying to correlate belief systems in non-white communitie
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by iskander 3y ago
...what happens in the next 50 years?
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by iskander 3y ago
I'm on a laptop and it looks totally fine to me.
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by iskander 3y ago
It's pretty readable at their large font size
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by iskander 3y ago
They're free but not accessible, it's a universe away from compassionate use access wrt practical availability.
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by iskander 3y ago
>This is how it already works - this is what a clinical trial is. That's not at all how clinical trials work. If and when someone decides to advance a drug to the next stage of development, it's done because they think there&#x
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by iskander 3y ago
Lots of cross-hatch patterns!

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