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gewa
searching Neon…
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1.
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by
gewa
5d ago
We are still living in a capitalistic society. We have to find a solution which is responsible, safe and returns on the investment. The commercial aspect can be true at the same time.
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by
gewa
5d ago
I agree, and even if it’s both marketing and safety, the safety side has a huge potential downside risk which we have to manage. Also, just out of curiosity, is there any historical precedent for a nascent, fast growing new industry screami
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gewa
4y ago
There's a recent startup which wanted to take taste prediction of luxury drinks to the next level with ML: https://www.mpg.de/18773206/the-signature-of-taste
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gewa
5y ago
It doesn't seem like you are very familiar with German politics or culture, but this is definitely an outlier. Freedom of speech is a central part of our constitution. Defamation is one of the very few ways and enforcement and interpre
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by
gewa
5y ago
As a German I have to emphasize that this has no support at all in Germany. The uproar was huge today and its seen as a misuse of power by the politician. Especially as he is not acting as a politician but as representative of the public of
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by
gewa
5y ago
This has no support at all in Germany. The uproar was huge today and its seen as a misuse of power by the politician. Especially as he is not acting as a politician but as representative of the public office of interior. The search warrant
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by
gewa
5y ago
Isn't this, what a housing cooperative are about? They are very common in Germany and seen as valuable cultural heritage. https://en.wikipedia.org/wiki/Housing_cooperative
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by
gewa
6y ago
I agree, the headline is definetly not what the research shows. See my other comment on non-neutralizing antibodies. Please change the title to the original one.
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gewa
6y ago
Please note, that neutralization by antibodies is only one of the many possible ways how our immune system can take action. Antibody recognition is still possible with the found mutant: "To determine whether 501Y.V2 is still recognized
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gewa
6y ago
Please note, that neutralization by antibodies is only one of the many possible ways how our immune system can take action. Antibody recognition is still possible with the found mutant: "To determine whether 501Y.V2 is still recognized
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by
gewa
6y ago
This Report from the COVID-19 Genomics UK Consortium gives a good summary of the prevalent genotypes with UK COVID-19 cases. You can see how the B.1.1.7 mutations N501Y + Δ69-70 and N501Y are very recent and mostly showed up during the last
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by
gewa
6y ago
In this case, the B.1.1.7 variant has shown to be highly abundant in recent COVID-19 cases in the UK. Much higher compared to other mutations which are tracked too. This is pretty clear evidence of an increased infection rate or evolutiona
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gewa
6y ago
Biochemistry by Jeremy M. Berg, John L. Tymoczko and Lubert Stryer is a widespread introduction to Biochemistry.
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by
gewa
6y ago
Nice to see you on the Frontpage, what an amazing project!. I remember you introduced me to HN 7 years or so ago at some MUN meeting hahaha.
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gewa
6y ago
No, the proteins are vitrified very rapidly in liquid ethane at approx. -200°C, so that the structure ist conserved.
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gewa
6y ago
Yes viruses are not alive and speaking strictly there are no clades or specieses. But I stopped beeing to strict with terminology like this on HN. Most people are not from this field and don't have broad prior knowledge and so it would
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by
gewa
6y ago
I don't think the article addresses the point right. Yes, there is only one strain of Sars-CoV-2 as the definition of a strain is a strict scientific term. Nevertheless, there are different clades [1] of Sars-CoV-2, which are character
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gewa
7y ago
I definitely agree about the superiority of RT-PCR and the drawbacks of direct detection. Nevertheless, seroconversion can take between 5-12 days from symptom onset [1]. Therefore it's important to outline the different ELISA strategie
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gewa
7y ago
Yes, there are of course drawbacks. But the direct detection is applicable at the same stage of infection as a rt-pcr and therefore usefull for immediate disease diagnosis. Indirect tests after seroconversion are the easier alternative, and
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gewa
7y ago
Maybe one should note, that there are two possible Elisa based strategies. Yes, You can present some viral protein to detect antibodies produced by the body after serum conversion, as you said. This serum conversion takes at least a week to
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gewa
7y ago
Unfortunately viruses are not microorganisms.
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gewa
7y ago
That is just not true. There were a few number of cases, where a second test was positive after initial curing. This is being investigated and can be attributed to issues with the test, false positive diagnosis in the first place or various
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Evolutionary Rate and MRCA of 2019-NCoV Based on the Current 27 Genomes
(virological.org)
3 points
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gewa
7y ago
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gewa
7y ago
I worked with Pandas and numpy for different projects, and I really like the low level component way how numpy works. In most cases where I used Pandas I regretted it at some point. OOP and numpy in the first place would’ve been a better so
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gewa
7y ago
Please remember, that these ontologies describe biological systems and are used as a standard for common nomenclature. It's orders of magnitudes harder to derive an ontology describing the localization of proteins in the cell by an alg
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gewa
7y ago
It's true, that different codons are transcribed with different speed but I've never heard that this would lead to differences in folding. Speed of translation is nevertheless used in order to signal shortage of amino acids or to
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gewa
7y ago
Im not sure if it's legally flawless to upload the published journal article to your Website and open it up to the public. As far as i know, you're only allowed to pass it on a personal, per-request basis. This explicitly refers t
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gewa
7y ago
Probably, but he's lucky anyways. For a Croatian fisherman, asking for 20,000 Kuna is like asking for 30 grand in the US.
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by
gewa
7y ago
Yes, but the ester will probably only affect the hydrophobicity and will be hydrolised at some point. I wouldn't expect vast differences in specifity.
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gewa
7y ago
This interview sounds like unpublished bullshit, it would never stand reviewing. To claim this from the survey they conducted is just wrong. Every science student learns about the difference between causation and correlation.
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