flobosg

11 ms·

1.
by flobosg 6d ago
> It was much quicker and easier to get the agar to 90C temperature by putting it in a microwave for 40s at 900W Agarose gels in molecular biology labs are prepared in a similar way. (Agarose is the main component of agar.)
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by flobosg 6d ago
No. In this case “Arctic Monkey” is just the pseudonym used by the guide writer.
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by flobosg 12d ago
Somewhat related: https://en.wikipedia.org/wiki/Long-term_experiment
4.
by flobosg 12d ago
(2002) https://en.wikipedia.org/wiki/Letter_to_the_American_People
5.
by flobosg 26d ago
(2007)
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by flobosg 1mo ago
They literally compose and print their letters in Excel.
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by flobosg 1mo ago
> You can do horrifying and amazing things with Excel. A friend of mine writes all of their correspondence in it.
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by flobosg 1mo ago
Blog entries, alas, are not.
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by flobosg 1mo ago
(2021)
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by flobosg 1mo ago
All those publications describe the methodology and modelling process to generate genomes, without testing them experimentally. This article shows that their designed genomes actually work in the wetlab. Your last two links are both preprin
11.
by flobosg 1mo ago
> Based on my quick reading, the BBC article doesn't bring up a prior publication / release from 2025 called "AI-Designed Phages," https://www.asimov.press/p/ai-phages That link is a commentary a
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by flobosg 1mo ago
The publication: https://www.science.org/doi/10.1126/science.aec2657 It is paywalled, but this seems to be the corresponding preprint: https://www.biorxiv.org/content/10.1101/2025.09.12.6
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by flobosg 1mo ago
> The from-the-hip cameras typically have a waist-level viewfinder That is the case with twin-lens reflex cameras, for example, which are not commonly used for street photography. What the GP meant was holding an SLR or rangefinder camer
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by flobosg 1mo ago
It goes both ways, of course. There are Germans who do not take learning English seriously, and foreigners who stumble because many informal expressions (including jokes) are difficult to express in German since they rely on structures that
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by flobosg 1mo ago
Thanks for this comment. I also arrived in Germany into a similar bubble, but shortly thereafter it burst. I was forced to relocate to a backwater shithole (trust me, I’m doing my best to be charitable here) where I had an extremely bad lif
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by flobosg 1mo ago
Brings to mind Jeff Bridges’ homepage: https://www.jeffbridges.com/
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by flobosg 2mo ago
For a bit of context, Party Cannon is a death metal band with this logo: https://en.wikipedia.org/wiki/Party_Cannon#/media/File:Party...
18.
by flobosg 2mo ago
According to the article metadata: "datePublished":"2026-07-16T08:18:37+09:00"
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by flobosg 3mo ago
The Nintendo 64 Disk Drive (64DD) had the Randnet Browser.
20.
by flobosg 3mo ago
> Mac Micro Mac Nano, just like iPods!
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by flobosg 3mo ago
> Yes, as supplementary information Still part of the article.
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by flobosg 3mo ago
Usually, journals require raw, unmodified data to be deposited as supplementary information.
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by flobosg 3mo ago
> I would be more worried if the blotted area was different (the dark blob) Or if more than one blob is present (i.e. blobs at different molecular weights) for a supposedly selective and specific antibody that should show exactly one blo
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by flobosg 3mo ago
From the article: > This image is supposed to demonstrate that the antibody being sold works as intended. (…) Antibodies are near-ubiquitous but notoriously fickle laboratory reagents in biomedical research. For many applications, it is
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by flobosg 4mo ago
Same with the TIM barrel fold. It can catalyze a wide range of reactions.
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by flobosg 4mo ago
> since the data used to train AlphaFold is limited to existing experimentally determined protein structures Protein sequences, but the point still stands.
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by flobosg 4mo ago
8G ought to be enough for anybody.
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by flobosg 4mo ago
A small nitpick: chlorophyll is the pigment, photosystems are the protein complexes containing it. > So it works. But there has got to be a simpler/better/non-toxic way to create an ion trap using proteins and make plants work
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by flobosg 4mo ago
> that structure is as/more important than sequence? Structure is determined by sequence, so they are equally important. Structure is more conserved than sequence, mainly due to the physicochemical constraints that govern protein
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by flobosg 4mo ago
My PhD thesis addressed a similar question. I did a survey of sub-domain sized fragments shared between different protein folds. It turns out that there are plenty, even among folds considered evolutionarily distant.

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