eweitz

5 ms·

1.
by eweitz 5mo ago
"RP11" is that man from Buffalo who comprises 74% of the human reference genome [1]. [1] https://undark.org/2024/07/09/informed-consent-human-genome-...
2.
by eweitz 5mo ago
Yes. For folks looking for more: * Celera genome, first published 2004: https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_000002115.1... * Human reference genome, first published 2001 and most recently updated in
3.
by eweitz 4y ago
User interfaces for biology have drastically improved over the last 10 years. Domain-specific tools like genome browsers, protein viewers, or phylogenetic explorers [1-3] almost all look and feel a lot better than they did in 2012. The bigg
4.
by eweitz 4y ago
https://eweitz.github.io/ideogram/related-genes - gene search recommendation engine paired with a web component for genome visualization
5.
by eweitz 5y ago
I'm more interested in read speed than write speed. I have about 2 MB of data that I fetch, parse and transform into a nested object for easy look-up by various types of keys. It consists of 6 other objects, and I'd guess it&#x2
6.
by eweitz 5y ago
Some notes towards those ends: WikiPathways supports advanced queries via their SPARQL API and UI. See [1] and [2]. I find WikiPathways nice because it lets logged-in users create and edit pathways, with a low barrier to entry. I've
7.
by eweitz 5y ago
I created Ideogram.js, a JavaScript library for chromosome visualization [1]. Ideogram supports genomic views to research and report findings on cancer, clinical variants, gene expression, evolution, agriculture, and more [2]. What previou
8.
by eweitz 7y ago
> refutation of the single source's work Janssens seems less skeptical of 23andMe's paper on polygenic score for type 2 diabetes [1][2], which -- interestingly -- positively cites the Khera 2018 paper on polygenic score for hea
9.
by eweitz 7y ago
Large genetic datasets yield medical progress by increasing statistical power of tests. These better tests enable earlier and more targeted treatment. Take heart disease. It has a significant but complex genetic component. Many genetic v
10.
by eweitz 7y ago
UK Biobank has a smaller cohort but deeper and more reliable data. All UK Biobank participants were tested for blood pressure, bone mineral density, grip strength, BMI, etc. The last 200,000 participants underwent detailed tests of cogniti
11.
by eweitz 7y ago
23andMe is CLIA certified and FDA authorized, and makes many medical claims. From [1]: "CLIA certification and CAP accreditation 23andMe laboratory testing is done in U.S. laboratories certified to meet CLIA (Clinical Laboratory Impro
12.
by eweitz 11y ago
> Manhattan has twice the people with half the land area, on an island. Manhattan has twice the residents based on U.S. Census population data, but actual daytime population is more than just residents. A more important statistic is c
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Meet one of the world’s most groundbreaking scientists. He’s 34.(statnews.com)
1 points by eweitz 11y ago|0 comments
14.
by eweitz 11y ago
Several major classics are oddly omitted from that list: - "The Art of Computer Programming" (TAOCP) - "The C Programming Language" (K&R) - "Structure and Interpretation of Computer Programs" (SICP) - &quot