dna4cy

5 ms·

1. 1.▲
   by dna4cy 5y ago

   In addition to what others have written (mainly, loss of tumor antigen target CD19) the antigen receptor (part of the CAR) can be recognized as foreign (FMC63 on human CD19 targeting CARs is mouse origin) and the body will generate an antib
2. 2.▲
   by dna4cy 5y ago

   Tumor vaccines are not at all equivalent to CAR-T. CAR-T involves genetically reprogramming T cells with information encoding a specific signal to find cancer, recognize it like a lock and key, and then destroy it. CAR-T > tumor vaccines
3. 3.▲
   by dna4cy 5y ago

   Founder CEO of LEAH Labs here. Our pilot studies in dogs with cancer are slated to start in April. We're first focused on the unmet need for dogs and working to build the first companion animal health company founded on gene editing ex