devaboone

7 ms·

1.
by devaboone 3y ago
I think doing an update would be great, when I have time. Just a note: the article you cited was not a randomized controlled trial. It is a meta-analysis that included only 2 small RCTs and a ton of observational studies. The image from my
2.
by devaboone 3y ago
I’m the author. In reading the comments here, there are some common questions and misunderstandings that I would like to address. First, about the patient being an outlier: I wrote the article because I see cases like hers pretty frequently
3.
by devaboone 3y ago
I wrote the article because I see cases like hers pretty frequently. She is an outlier in the severity of her symptoms, but not an outlier in getting Vitamin D toxicity from 5,000 units daily. I get at least one patient a week contacting me
4.
by devaboone 3y ago
Also, Michael Holick is a controversial figure. A lot of the articles pushing high doses of Vitamin D lead back to him. Please read this NY Times article for a great summary of his issues: https://www.nytimes.com/2018/0
5.
by devaboone 3y ago
This is one case report. Yes, this person took an insane amount of Vitamin D and ended up very sick from it. But we can't really conclude that amounts under her dose are safe.
6.
by devaboone 3y ago
It's really important to follow the sources when you see something like this quoted. The article you link to is not an actual study in which people were given Vitamin D. It is a review article, and the specific sentence you quote refer
7.
by devaboone 3y ago
There is a big difference between Canada and the US in how Vitamin D is treated. In the US, you can go into any major pharmacy chain like CVS or Walgreens and purchase Vitamin D over the counter in 5,000 unit pills, with the bottle instruct
8.
by devaboone 3y ago
Hey there! I'm here now and will try to respond to everything brought up. Some of the confusion stems from the complexity of the issue. There has been a lot of research on the clinical role of Vitamin D, much of it of questionable qual
9.
by devaboone 4y ago
I am a physician (specialty surgeon) in the US, so can comment from that perspective. Clinical documentation is often the bane of my existence, so there is definitely a need for innovation. But entering this market (in the US, anyway) may b
10.
by devaboone 5y ago
For example, the comment from Paul Gambill, the CEO of Nori who is quoted extensively in the article. He wrote in to clarify that he does not agree with the title and that he does in fact think that afforestation is necessary.
11.
by devaboone 6y ago
For those interested in Vitamin D and Covid, here is a summary of the research so far: https://www.devaboone.com/post/vitamin-d-and-covid
12.
by devaboone 6y ago
I see Vitamin D toxicity at MUCH lower doses than in this case report. Here is my description of one patient: https://www.devaboone.com/post/vitamin-d-part-2-shannon-s-st... Most of the patients I see with vitamin D to
13.
‘‘Am I the Asshole?’’ Reveals America’s Sexist Underbelly(gen.medium.com)
3 points by devaboone 6y ago|1 comments
14.
by devaboone 6y ago
The headlines on Vitamin D and Covid far surpass the actual data. Here is my summary on the latest research: https://www.devaboone.com/post/vitamin-d-and-covid
15.
by devaboone 6y ago
Which fields put names in alphabetical order? In medicine, at least, deciding who goes in the first and last name spots is a really big deal, and fights over this sometimes ruin professional relationships.
16.
by devaboone 6y ago
The chart is only regarding RCTs. In the best individual trials that we have, it does not show a benefit for respiratory infections. But we do see some suggestion of benefit in meta-analyses. In general, if the meta-analysis shows somethin
17.
by devaboone 6y ago
I don't think it is all due to sampling error. In my article I mention that one of the areas in which Vitamin D shows promise is with respiratory illness. I think there likely is an effect, just not as dramatic as the headlines are mak
18.
by devaboone 6y ago
I wrote the article. It was very hard to write a concise article about all of Vitamin D research, and so I didn't have space to address it, though I really appreciate the feedback. Race and Vitamin D is an interesting area. The VITAL
19.
by devaboone 6y ago
I wrote the blog post. Unfortunately I was not able to include every study on Vitamin D, and had to pare it back to the largest and/or most significant studies. Most of the studies you mention are small and published in obscure journal
20.
by devaboone 6y ago
Here is what the article states: "Therefore, a multivariate logistic regression analysis was performed to adjust the model by possible confounding variables such as hypertension and type 2 diabetes mellitus for the probability of the a
21.
by devaboone 6y ago
I tried really really hard to put in all of the most significant studies on Vitamin D. Small, low-quality studies didn't make it in, but the major trials did.
22.
by devaboone 6y ago
I didn't watch the whole video but I read the study. There is a lot of excitement about this study, but the details in it matter. It was randomized - but when you look at the two groups (treatment vs. control), they had some key differ
23.
by devaboone 6y ago
There is a lot of excitement about this study, but the details in it matter. It was randomized - but when you look at the two groups (treatment vs. control), they had some key differences. The control group (who didn't receive Vitamin
24.
by devaboone 6y ago
That is a reasonable hypothesis. Also, people who are very ill are less likely to get outside and get enough sun, so they will develop low Vitamin D. Vitamin D is likely a marker of poor health. (Once the Vitamin D gets low enough, we do se
25.
by devaboone 6y ago
Thanks for the feedback. I will edit the article to specify that she was NOT taking any calcium throughout all of this. This is not uncommon - Vitamin D seems to be more effective at raising calcium levels than calcium itself. I do take is
26.
by devaboone 6y ago
This is exactly it. I was able to see it because I deal with this every day. I am not more holistic than other doctors; I just know how to look at calcium and Vitamin D levels.
27.
by devaboone 6y ago
This is a correlation. There are lots of conditions that are associated with low Vitamin D. Mortality overall is associated with low Vitamin D. But it doesn't mean that the low Vitamin D caused any of these problems. Having overall poo
28.
by devaboone 6y ago
I really like the Cochrane reviews, and love that they periodically update areas when there is more recent research. And you are correct, their articles on Vitamin D have become less enthusiastic with time. This makes sense I think, since t
29.
by devaboone 6y ago
Thanks! Yes, I am very new to this. Hoping that by continuing to write, I'll get better. The comments on here are great for helping me understand how things are interpreted.
30.
by devaboone 6y ago
The problem is that a lot of people taking Vitamin D may not need it. The percentage of the population with vitamin D deficiency depends on your definition of deficiency - and that changes. From large trials in humans, there is very little

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