davemessina

5 ms·

1. 1.▲
   Cofactor Genomics (YC S15) Is Hiring a Marketing Specialist in SF(cofactorgenomics.recruiterbox.com)

   1 points by davemessina 8y ago
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   Cofactor Genomics (YC S15) Is Hiring an Account Executive (Sales)(cofactorgenomics.recruiterbox.com)

   1 points by davemessina 8y ago
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   Cofactor Genomics (S15) Is Hiring a Computational Scientist(cofactorgenomics.recruiterbox.com)

   1 points by davemessina 8y ago
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   Cofactor Genomics (YC S15) Is Hiring a Senior Software Engineer(cofactorgenomics.recruiterbox.com)

   1 points by davemessina 9y ago
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   Cofactor Genomics (YC S15) Is Hiring a Full-Stack Software Engineer(cofactorgenomics.recruiterbox.com)

   1 points by davemessina 9y ago
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   Cofactor Genomics (YC S15) Is Hiring a Senior Product Development Manager(cofactorgenomics.recruiterbox.com)

   1 points by davemessina 9y ago
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   Cofactor Genomics (YC S15) Is Hiring a Lead Generation Specialist(cofactorgenomics.recruiterbox.com)

   1 points by davemessina 9y ago
8. 8.▲
   by davemessina 11y ago

   Hi Jake, While we have no immediate plans to hire out west, we are changing rapidly and that certainly could change in the future. We'll be offering our test to patients through doctors and hospitals — imagine going for your annual che
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   by davemessina 11y ago

   I am not an expert in gene therapy, but I think getting the transcription or translation machinery to read the "good" copy instead of the stop codon would be the challenge there. circRNA have so much value already as a way to diag
10. 10.▲
    by davemessina 11y ago

    Hi everyone! Dave Messina from Cofactor Genomics here. I'd be happy to answer any questions you might have.
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    by davemessina 11y ago

    Over half of the YC companies (us included) don't really need the money. The $120k investment is only a small part of what YC does. See http://www.ycombinator.com/atyc/
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    by davemessina 11y ago

    Yes.
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    by davemessina 11y ago

    Thanks for your comments, and yes, you've got it exactly. In cancer, both DNA and RNA can be effective diagnostics, and there's been a lot of great work on the DNA side in cancer. In essentially all other diseases, though, there a
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    by davemessina 11y ago

    That some circRNAs are lower in cancer than in normal tissue is a reliably detectable difference and is precisely what makes them an excellent biomarker. There's additional evidence shown here: "Using circular RNA as a novel type
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    by davemessina 11y ago

    It's the fastest way for us to get this powerful diagnosis technology on the market and helping people. We believe that our RNA test can become a routine part of a doctor's visit, both as an early indicator of disease and — if the
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    by davemessina 11y ago

    Hi Daniel, We've filed patents on our work. Is there any biotech patent landscape as bad as RNAi? :)
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    by davemessina 11y ago

    Here's a good place to start: http://dx.doi.org/10.1038/cr.2015.82
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    by davemessina 11y ago

    We are looking at Parkinson's, heart disease, and cancer initially.
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    by davemessina 11y ago

    We plan to offer testing through your doctor, rather than direct to consumer. We are measuring circular RNAs.
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    by davemessina 11y ago

    Hi, Great question. We're developing tests around a recently discovered type of RNA called circular RNA. Tissue-specific circular RNAs are present in blood, and so that's how it's possible to use a blood test instead of havin
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    by davemessina 11y ago

    Hi everyone! Dave Messina from Cofactor Genomics here. I'd be happy to answer any questions you might have. We're excited to launch!