charlysisto

6 ms·

1.
by charlysisto 3mo ago
Yes magnesium seems to be quit a common deficiency because the heavy use of fertilizer depletes the density of minerals in the food chain. Also magnesium is a very important co-factor in the use of Vit D, so supplementing with a magnesium d
2.
by charlysisto 10mo ago
Probably a joke... nevertheless I had the same reaction ! It exercises your deduction, binary thinking, also stochastic vs systematic methodology (first look around randomly find the most obvious before going number by number). Getting to
3.
by charlysisto 2y ago
Yes I remember Dr Bikman saying that and it make sense since it is a form of uncontrolled electrical storm in the brain analagous in that sense to epilepsy. The main theoretical idea behind mitochondrial dysfunction is that it is a root cau
4.
by charlysisto 2y ago
Apparently they play a critical role in neurones (which can have millions of them) not only because the brain is the most energy hungry organe but also because they play numerous parts in how they work : neurotransmitter transporters and re
5.
by charlysisto 2y ago
Chris Palmer, Harvard Psychiatrist has written a book called "Brain Energy" about the potential effects of Ketogenic therapy. The crux of his theory relies on Mitochondria's health which play essential roles (serotonine dopam
6.
by charlysisto 3y ago
I agree and think that's the main point of the story not AI, however questionnable it's usage may be
7.
by charlysisto 3y ago
Evolution indeed gave us fat storage which is one of those traits becoming unnecessary in the post industrial world of abundance. The problem is our body is more adapted to the too little rather than to the too much. E.g: fasting comes with
8.
by charlysisto 3y ago
I heard this a few times in the ruby community by some well known figures like Sandy Metz. Simple example : time related tests can be cumbersome to setup, but if you inject time in the method, test becomes easy, incidentally improving your
9.
by charlysisto 3y ago
And maybe we should mention the elephant in the room : the environmental price
10.
by charlysisto 3y ago
I don't know much about the gut microbiome, but it is pretty well established now that the ketones produced by fasting (or diet mimicking it like keto) have a powerful effect on the brain : as an alternative to glucose for fuelling neu
11.
by charlysisto 4y ago
You have a point but that would mean Russia cares about contractual ramifications - not sure about that ! On the other hand blowing up the pipe means giving up on : 1. blackmailing the europeans if they don't comply to some demands.
12.
by charlysisto 4y ago
> Russia because they could put pressure on Europe. That doesn't really hold because they could just turn off the tap
13.
by charlysisto 4y ago
I can only join the chorus and sing the praises of Ryan Bates. Railscasts was a blessing, I checked his videos almost every day. Sad when he left - spoiler alert, some sort of burnout I understood at the time... Ironically I now work for a
14.
by charlysisto 6y ago
Makes me wonder if you have the corollary concept : Social Heating... my feeling is social media has a multiplicative effect on both sides of the thermometer
15.
by charlysisto 7y ago
"that article pretty much nailed it" comment would probably be somewhere in its 29 steps :)
16.
by charlysisto 7y ago
Very impressed to find Jancovici here. I've been watching his intervention for 6 months and I found he has one of the most rational approach to our coming world. It is bleak but not desperate, although his main message is : technology&
17.
by charlysisto 7y ago
on the long term probably, the idea (I have heard from diverse sources) is that only nuclear power can ensure the transition from carbon to sustainable energy in order to avoid to avoid a catastrophic++ climate change
18.
by charlysisto 9y ago
Phone for me is an intrusion when it's not very close people. I tend to hate phone as well but if the conventions around phoning changed like, you'd systematically agree through messaging on a certain moment to call etc I guess I
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by charlysisto 9y ago
Excellent idea, there's a huge market for new phone management apps it seems, what are we waiting for
20.
by charlysisto 9y ago
I wrote nexter ( https://github.com/charly/nexter ) a few years ago without knowing I was applying the keyset principle (it's not pagination though but a next page library). It works well on a consistent data set b
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by charlysisto 9y ago
Did that Iceberg rollover when it heard the news today ?
22.
by charlysisto 9y ago
I am biased because I read HN daily and kind of assume everybody does - including the author of the story. Which is silly... Nevertheless I strongly believe in the presumption of innocence, even outside of court, as a general moral rule we
23.
by charlysisto 9y ago
Although some of these hypotheses are vaguely plausible I think it is outrageous to lay all the suspicion on a potential victim. I'm not saying we should be naive and take everything for granted in this story but the least we can do is
24.
An exciting new idea in Basic Income(medium.com)
2 points by charlysisto 10y ago|0 comments
25.
by charlysisto 10y ago
I would argue that the more intuitive principle behind composition is the "Single Responsibility" one. Although it is correlative to the idea of 'program to an interface' (aka don't mingle with the state from the in
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by charlysisto 10y ago
It's funny to see in the life cycle of every new language/framework in the block the rediscovery of good architectural patterns that can be summed up in one sentence: - inheritance & mixin bad / composition good. Good art
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by charlysisto 10y ago
A simple formula to take a lot of AR's bloat away is to use it mainly as a read library (AR's great for generating complex queries in a simple & readable manner). For write operations (aka user interaction) I use a combination
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by charlysisto 11y ago
Business is a part of society, not the other way round.
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by charlysisto 11y ago
This type of complexity should be covered by architecture (SRP & composition) not tests. The main value of test is revealing the flaws of your code, not making sure it works at all cost.
30.
by charlysisto 11y ago
Immutability, stateless function (or referential transparency), the ability to reason about state, the edge it gives to concurrency etc these are all valid, and objective arguments. It might not be the end of the discussion but at some poin

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