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burning_hamster
searching Neon…
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7 ms
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burning_hamster
1y ago
I was going to call BS on this one, but after crunching some numbers, if anything this is likely an underestimate. human nuclear genome size (haploid): 3.1 billion bp mitochondrial genome size: 16 000 bp 1 human nuclear genome per egg ->
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burning_hamster
1y ago
I disagree. > I think it would be better to describe this as an ‘organelle’ transplant as it would be easier for people to understand and discuss. Unlike previous attempts, the donor mitochondria are not transferred into the mother egg.
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burning_hamster
1y ago
Natural sciences: about 3 years at best. You finish your degree, and start your PhD. The first year, you are busy learning techniques and getting caught up with the relevant literature. You are far too concentrated on learning new things to
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burning_hamster
1y ago
> A Dutch speaker can't read or understand German. A Dutch speaker can't necessarily read or understand German. However, a Dutch person nearly always does, and often flawlessly so.
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burning_hamster
1y ago
Garten / garden derive from garte / yard, which just meant an enclosed outdoor space.
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burning_hamster
1y ago
Huge fan of Distill here (and your personal blog). > In retrospect, I deeply regret trying to run Distill with the expectations of a scientific journal, rather than the freedom of a blog, or wish I'd pushed back more on process. Not
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burning_hamster
1y ago
The range notation indicates 95% confidence intervals, not the minima and maxima. If the lower bounds are close enough to zero (and the interval is large enough), then there may some residual probability mass associated with negative values
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burning_hamster
1y ago
I am a biochemist and neuroscientist and also thought it was fantastic read. It's rare that someone manages to cater to both audiences this well. Kudos!
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burning_hamster
1y ago
Some animals get most if not all of their sleep through microsleep [1]. So whatever mechanism "refreshes" the brain, it can work on short time scales. The switch in brain firing dynamics from wake to sleep (NREM) is very fast --
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burning_hamster
2y ago
It is worth noting that these topical applications are quite controversial in the medical literature. The evidence supporting a dermal absorption of magnesium (or other electrolytes) is pretty poor [1]. In that sense: yes, it would be excee
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burning_hamster
2y ago
It is worth noting that these topical applications are quite controversial in the medical literature. The evidence supporting a dermal absorption of magnesium (or other electrolytes) is pretty poor [1]. [1] https://pmc.ncbi.nlm.n
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burning_hamster
2y ago
In theory, there is enough magnesium in your bones (~12 g) to cover your RDA (~400 mg) for 30 days [1]. However, only a third of that is available without strongly negatively affecting your health. So if your Mg stores are full (if!), then
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burning_hamster
2y ago
> For example, let's say instead of gradient descent you want to do a Newton descent. Then maybe there's a better way to compute the needed weight updates besides backprop? IIRC, feedback alignment [1] approximates Gauss-Newton
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burning_hamster
2y ago
> it always automatically happens This is exactly the framing the author is criticizing. It assumes that the placebo effect is a constant that cannot be improved upon, and thus deserves no consideration, when designing the treatment. How
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burning_hamster
2y ago
> sizeable camps on both sides There are dozens of us! Mostly because Nedergaard's lab(s) are like 50 people all by themselves. I always find it interesting what people's perception of the size of academic subfields is. For mos
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burning_hamster
2y ago
I am also not a fan of the pivot to Snap. However, it is worth mentioning, that it has only been two years (I think, at least 22.04 LTS was the first release I had to wrestle with them on my machine), and the experience has become a lot bet
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burning_hamster
2y ago
You are referring to the critical period [1] of (second) language acquisition, which is generally thought to end with the onset of puberty [2]. Neurodevelopmentally, this period coincides with extensive synaptic and dendritic pruning and i
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burning_hamster
2y ago
> I find I feel more rested with more REM cycles which generally means REM starts earlier. This is probably the case because your NREM / slow-wave sleep need was low to begin with. If you go to bed relatively rested, it's easy
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burning_hamster
2y ago
> The data quality of wearables to detect sleep stages is in the 90%+ accuracy range now. Citation needed.
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burning_hamster
3y ago
> Yes I’ve made a whole procedural map generator & renderer just for this example, and I have zero regrets. You can be salty about excessive use of animations in modern UI all day long, but you have to respect that level of commitmen
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burning_hamster
3y ago
Not to mention a fantastic writer. Already his PhD thesis was brilliant, and one of the few [1] I have ever read cover-to-cover. "Advanced data analysis from an elementary point of view" is one of my go-to recommendations for peop
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burning_hamster
3y ago
Some octopus species use rudimentary tools, which would put them ahead of elephants and whales in at least that aspect.
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burning_hamster
3y ago
This grug not big brain. This grug ate food and read article on big screen at the same time. Now food on screen, not in belly. Grug still hungry, but need to find rag now to clean screen. Otherwise no more work and no more shiny rocks for g
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burning_hamster
3y ago
Oh, I misunderstood you then. I thought you meant classical Greek in general. My apologies.
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burning_hamster
3y ago
That's nonsense. Greek has prepositions, conjunctions, and cases that leave little room to interpretation. It is a rather precise language (much more so than English or even Latin).
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burning_hamster
3y ago
Arguably, there have been a good number of wars (ostensibly) over books (in particular religious texts seem to do the trick), whereas we are yet to declare war over any form of web content.
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burning_hamster
3y ago
> A proto-FaceGramTok I love it. Though FaceTokGram rolls off the tongue easier.
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burning_hamster
3y ago
Throwing a lot of money at one single approach doesn't validate that approach or make it magically successful. It gives one group of people the ability to try out more than just one idea (unlike typical grants that let you maybe work o
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burning_hamster
3y ago
Indeed, it's the classical Weismann's fallacy. From Nick Lane's 'Life Ascending': > The most popular idea, dating back to Weismann in the 1880s, is wrong, as he himself was quick to recognise. Weismann originally
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burning_hamster
3y ago
Due to the blood-brain barrier, it is quite difficult to get substances injected into the blood into the brain (though some obviously do, otherwise there would be no psychoactive substances). Injecting into brain tissue directly is possible
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