boas

8 ms·

1.
In Situ Cancer Vaccine(mdpi.com)
3 points by boas 1mo ago|1 comments
2.
by boas 1mo ago
Immunotherapy can help the immune system attack cancer cells, but it often works poorly for liver metastases, where immune responses are naturally suppressed. This study proposes a new way to deliver immune-stimulating drugs directly into l
3.
by boas 3mo ago
The latest publication from my lab is a new intratumoral immunotherapy delivery platform, which achieves 6 days of intratumoral drug release, from a single injection. Tumors can be “painted” with drug using a needle, and the drug stays exa
4.
Programming the immune system with timed local drug delivery(link.springer.com)
3 points by boas 3mo ago|2 comments
5.
by boas 3mo ago
The immune system is like a computer, which uses chemical signals, instead of electrical signals. When the immune system sees a potential threat, it needs to integrate information from multiple sources, to decide how to respond. Making th
6.
by boas 10mo ago
Instead of major surgery, tumors can be treated by blocking off the artery supplying the tumor, thus starving the tumor of nutrients and oxygen. This is a common treatment for liver tumors, and this paper now shows that the same thing can
7.
Treating pancreatic tumors via the pancreatic artery(pubmed.ncbi.nlm.nih.gov)
2 points by boas 10mo ago|1 comments
8.
by boas 2y ago
OpenSCAD file for the barbed catheter: https://static-content.springer.com/esm/art%3A10.1038%2Fs415...
9.
by boas 2y ago
When the immune system encounters a new antigen, it needs to make a decision about whether to attack, or to ignore. Making the correct decision is important for fighting infections, killing cancer cells, and avoiding autoimmune diseases.
10.
3D printing catheters using microstereolithography(nature.com)
4 points by boas 2y ago|2 comments
11.
Show HN: Bee stinger catheter for directly injecting drugs into tumors(rdcu.be)
1 points by boas 2y ago|0 comments
12.
by boas 4y ago
That's the system we had in the 1970s (government owned the patent to government-funded research). And what happened is that the government didn't know what to do with the patents, and the inventors, who were best positioned to c
13.
by boas 4y ago
> Life would be simpler if only these hospitals could set aside their arrogance and just go with the recommended workflow! This would be like asking programmers to standardize on the recommended programming language. we would love to jus
14.
by boas 5y ago
In a hospital or healthcare system, all of the doctors can generally see all of the imaging, labs, and notes for all patients. The problem with "curbside consults" -- where another doctor provides an immediate opinion without see
15.
by boas 5y ago
Interventional radiologist here. The short answer is "no." I personally perform more than 100 different types of procedures, but there are lots of variations of each procedure, and different techniques for performing the same pr
16.
by boas 5y ago
Another thing to keep in mind is that “one” procedure often involves multiple CPT codes. Sometimes the CPT codes change during the procedure, based on what the surgeon finds. The hospital should be able to give you an estimate of the cost
17.
by boas 5y ago
Yes, we induce pancreatic cancer in pigs, and then we try to treat the cancer. One important question is why so many new cancer treatments are successful in mice and rats, but then fail in human trials. You could point to genetic differenc
18.
by boas 5y ago
We've tried the organoid approach, but ultimately, you need an animal model to properly model blood flow, immune response, etc. So we developed a pig model of pancreatic cancer: https://journals.plos.org/plosone/a
19.
by boas 5y ago
If the fluoro (X-ray) machine fails during a procedure, you can either bring in a portable C-arm, or move the patient (mid-procedure) to a different procedure room with working equipment. If the power goes out and the backup generator fails
20.
by boas 6y ago
p value by Fisher's exact test is 0.007. It's a significant difference.
21.
by boas 6y ago
> Vista[0] (the VA's EMR) is pretty scary. I wouldn't wish it on anyone. why do you say that? From a doctor's perspective, Vista is one of the more user friendly EMRs.
22.
by boas 11y ago
Here's a normal brain MRI, compared to photographed slices of a brain: https://www.claripacs.com/a.php?a=vw (Click and drag to scroll. "Share > Download" to download the full DICOM data) This site has tho
23.
by boas 11y ago
Thanks! I'll look into this. I also use g++ on Linux, so a cross-platform solution would be nice.
24.
by boas 11y ago
A lot of the radiology software that I write involves iterating over a 3D grid. The auto-parallelizer lets you easily process each 2D slice on a different processor core. My laptop has 2 cores x 2 hyperthreads per core = 4 virtual cores,
25.
Auto-parallelizer: #pragma loop
2 points by boas 11y ago|3 comments
26.
by boas 13y ago
I wish that on AWS, you could create EBS volumes larger than 1 TB. I know you can set up RAID to get > 1 TB, but it'd be nice if Amazon handled this automatically.
27.
by boas 13y ago
We developed an easy way to email and collaboratively view CT or MRI studies. http://www.claripacs.com .
28.
by boas 13y ago
The US post office is amazing. They can deliver a letter cross country, door-to-door, for 46 cents! In my experience, USPS and Gmail's spam filter lose important mail at similar rates, < 1%. This is based on how frequently my credit
29.
by boas 13y ago
Do you sign business associate agreements with your colo facility, ISP, and landlord? They also are physically capable of accessing your data, even though they are legally or contractually forbidden from doing so.
30.
by boas 13y ago
According to Amazon, their employees are not allowed to access to your data, so you don't need to sign a business associate agreement with them to be HIPAA compliant. I imagine this is similar to how sending patient information through the

More ›