bnprks

5 ms·

1.
by bnprks 8mo ago
With genomics, your data is probably write ~once, almost entirely numeric, and is most likely used for single-client offline analysis. This differs a lot from what most SQL databases are optimizing for. My best experience has been ignoring
2.
by bnprks 2y ago
Amusingly, (to me at least) there's also an SSE instruction for non-reciprocal square roots but it's so much slower than reciprocal square root that calculating sqrt(x) as x * 1/sqrt(x) is faster assuming you can tolerate the
3.
by bnprks 2y ago
Yeah, I think DRAM is almost certainly the future, just in terms of being able to afford the memory capacity to fit large models. Even Cerebras using a full wafer only gets up to 44 GB of SRAM on a chip (at a cost over $2M). An interesting
4.
by bnprks 2y ago
Seems like the claims of the abstract for speed and energy-efficiency relative to an RTX 3090 are when the GPU is using a batch size of 1. I wonder if someone with more experience can comment on how much throughput gain is possible on a GPU
5.
by bnprks 2y ago
The article also gives reason to be skeptical of the quoted "10 fatalities out of an estimated 3.65 million jumps in 2023". If we count 28 known fatalities at this one facility from 1983 to 2021, we get around 0.75 fatalities per
6.
by bnprks 2y ago
Thanks for the link, and very good to know. I've always struggled to find component prices for Kioxia drives and higher-capacity RAM sticks so it's good to see I can finally look these up on serversupply when I'm curious.
7.
by bnprks 2y ago
Are you sure you're comparing equivalent memory and storage specs? I needed to go into the customization menus in the Dell configurator to spec something equivalent, where prices started going up quite rapidly. For example "3.2TB
8.
by bnprks 2y ago
The specifications page [1] gives a bit more context. I think minimum buy is about a half rack, which includes at least 16 64-core CPUs, 16 TiB of RAM, and 465.75 TiB of NVMe SSD storage. Playing around a bit with the Dell server configurat
9.
by bnprks 2y ago
If the function chooses to overwrite the value of a variable binding, it doesn't matter how it is defined at the call site (so inner x wins in your example). In the tidyverse libraries, they often populate a lazy list variable (think p
10.
by bnprks 2y ago
The good news is that most variables in R are immutable with copy-on-write semantics. Therefore, most of the time everything here will be side-effect-free and any weird editing of the variable bindings is confined to within the function. (T
11.
by bnprks 2y ago
One of the wildest R features I know of comes as a result of lazy argument evaluation combined with the ability to programmatically modify the set of variable bindings. This means that functions can define local variables that are usable by
12.
by bnprks 2y ago
To my knowledge AlphaGo models never became meaningfully available to the public, but 8 years later the KataGo project has open source, superhuman Go AI models freely available and under ongoing development [1]. The open source projects tha
13.
by bnprks 3y ago
I'm sorry about negative experiences and/or regrets other commenters might have about their vaccinations. Measuring the risk/reward profile of vaccines seems far from simple, particularly in cases like this where the large be
14.
by bnprks 3y ago
Strong second for wishing they tried physically testing some model output. The importance of "model that makes outputs AlphaFold thinks look like Cas" is very different from "model that makes functional Cas variants". Fo
15.
by bnprks 3y ago
Sadly even SSE vs. AVX is enough to often give different results, as SSE doesn't have support for fused multiply-add instructions which allow calculation of a*b + c with guaranteed correct rounding. Even though this should allow CPUs f
16.
by bnprks 3y ago
I hope this is just the start of egress fee changes in response to the European Data Act. Taking a look at other parts of the law's text [1], I think this change related to Article 25, but Article 34 section 2 is what really stands out
17.
by bnprks 3y ago
Yeah, the crux of the issue would definitely be whether use of an API is prohibited by default under copyright law for a country (i.e. does using a library make something a derivative work of the library). In the US, at least, the Google v
18.
by bnprks 3y ago
I think it is known that the Chinese state is making genetic databases of these minority populations and is taking genetic samples without consent. It's also known that the Chinese state is committing human rights violations against th
19.
by bnprks 3y ago
Looking closer at the GPL, it seems like most requirements only kick in once you "convey" GPL-covered code. If you make your users get the GPL component themselves from a 3rd party (e.g. PyPI or other package repository), then you
20.
by bnprks 3y ago
I think this 2019 article from the NY Times gives a reasonable introduction [1]. In short, the concern is that China is developing genetic databases as part of its state surveillance and repression of the Uighur people in Xinjiang. So the i
21.
by bnprks 3y ago
I appreciate that the authors released code and weights with their paper! This is the first high-profile DeepMind paper I can recall that has runnable inference code + checkpoints released. (Though I'm happy to be corrected by earlier
22.
by bnprks 3y ago
> Other tasks required studying the input data I also felt there were more problems than usual this year that could not easily be solved without looking at the input for special cases not alluded to in the problem descriptions. (As someo
23.
by bnprks 3y ago
I believe McFly hangs on to all history in the database, though you can limit the UI to only return the most recent entries (MCFLY_HISTORY_LIMIT). One side note -- I made a small tool to integrate the McFly database with the fzf UI, which m
24.
by bnprks 3y ago
Reading the methodology of the underlying paper makes this estimate seem quite dubious. Quoting from the paper [1]: > Due to lack of data, we assumed that revenue per minute of platform use was constant by age. Surely ad rates targeting
25.
by bnprks 3y ago
Though there are a couple caveats as to what code is available. Quoting from the github: > implementation contains an implementation of the evolutionary algorithm, code manipulation routines, and a single-threaded implementation of the F
26.
by bnprks 3y ago
The first sentence of the article claims 9.6 TB/s speeds, but the linked press releases only claim 9.6 Gbps -- 8000x slower
27.
by bnprks 3y ago
Agree 100%. I've always found it surprising there isn't a requirement for symmetric bandwidth charges. I think it's fine if AWS wants to have expensive bandwidth, but having free ingress + exorbitant egress seems like a trans
28.
by bnprks 3y ago
My new made-up email approach is using admin@$COMPANY in the hopes that they'll send the spam to themselves
29.
by bnprks 3y ago
At the time I bought my Framework, I paid $1,200 for a DIY edition including 3rd party purchase of 32GB RAM and 1TB SSD (Samsung 980 Pro). The cheapest Apple laptop that can be configured to those RAM and storage specs is the 14" Macbo
30.
by bnprks 3y ago
Should this title be updated to "Tracking a single person through wastewater viral RNA "? The SARS-CoV-2 genome is RNA [1], and this is presumably what's being measured by this virology researcher. The tweets don't spec

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