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bede
searching Neon…
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1.
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by
bede
7d ago
Seems not to be blacklisted, but I see the domain is only 22 days old, so that'll be it I imagine.
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by
bede
7d ago
FYI https://race-term.com is blocked by NCSC's Protective DNS service using my UK University's connection. Are you sure your domain is not blacklisted somewhere?
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by
bede
12d ago
Thanks for sharing data. I suspect this effect is heavily stratified across demographics. After a point, how much someone chooses to spend on their car is about their values more than their wealth. I once lived in a street with many parked
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by
bede
12d ago
"As vehicles are reliable indicators of a person's social rank and wealth" The wealthiest Europeans I know drive the cheapest vehicles. Modesty is wealth in many parts of the world, but perhaps not in California (the authors
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by
bede
5mo ago
I too would far rather bear a token cost than have my sessions rot silently beneath my feet. I usually have ~5 running CC sessions, some of which I may leave for a week or two of inactivity at a time.
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by
bede
5mo ago
Thanks for publicising. I recently decided not to renew my Backblaze in favour of 'self hosting' encrypted backups outside the US. But I was horrified to learn that my git repos may not have been backed up, nor my Dropbox, whose s
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by
bede
6mo ago
> Probably obvious for many, but I didn't realize ACs don't transport any air into the room, but just moves it around I had the same epiphany as you days after acquiring a CO2 monitor. Most people notice poor indoor air quality
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by
bede
8mo ago
> There’s another distance limit at work here, and that is the speed of light. It takes milliseconds for the signal in your phone to reach the hotel above ground and be handed over to the mobile network. It takes roughly 100us for light
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by
bede
1y ago
For BAM this could be a good place to start: https://www.htslib.org/benchmarks/CRAM.html Happy to discuss further
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by
bede
1y ago
Author of [0] here. Congratulations and well done for resisting. Eager to try it! Edit: Have you any specific advice for training a fasta compressor beyond that given in e.g. "Using OpenZL" ( https://openzl.org/gett
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by
bede
1y ago
A Zstd maintainer clarified this: https://news.ycombinator.com/item?id=45251544 > Ultimately, Zstd is a byte-oriented compressor that doesn't understand the semantics of the data it compresses
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by
bede
1y ago
Fascinating, thank you.
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by
bede
1y ago
Thanks for reminding me to benchmark this!
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by
bede
1y ago
Yes, when doing anything intensive with lots of sequences it generally makes sense to liberate them from FASTA as early as possible and index them somehow. But as an interchange format FASTA seems quite sticky. I find the pervasiveness of
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by
bede
1y ago
BAM format is widely used but assemblies still tend to be generated and exchanged in FASTA text. BAM is quite a big spec and I think it's fair to say that none of the simpler binary equivalents to FASTA and FASTQ have caught on yet (XK
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by
bede
1y ago
Thank you for clarifying this – yes the non-semantic nature of these particular line breaks is a key detail I omitted.
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by
bede
1y ago
Exactly. The line breaks break the runs of otherwise identical bits in identical sequences. Unless two identical subsequences are exactly in phase with respect to their line breaks, the hashes used for long range matching are different fo
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by
bede
1y ago
Yes I'd expect a dict-based approach to do better here. That's probably how it should be done. But --long is compelling for me because using it requires almost no effort, it's still very fast, and yet it can dramatically impr
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by
bede
1y ago
Yes, it sounds like 7-Zip/LZMA can do this using custom filters, among other more exotic (and slow) statistical compression approaches.
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Removing newlines in FASTA file increases ZSTD compression ratio by 10x
(log.bede.im)
279 points
by
bede
1y ago
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113 comments
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by
bede
1y ago
Just watched my iPhone 15 battery drop 2% scrolling for <60s
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by
bede
1y ago
Thank you, perhaps the parent can be edited to use this URL instead
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bede
1y ago
I assumed that the article must be about a frustrated CDC employee just trying to get internet access at work.
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by
bede
3y ago
I also lost faith in certain scientists (and many more politicians) during the pandemic. But be wary of generalising about a such a large and interdisciplinary group of people. Voices amplified by the media (indeed like Robert Malone on Rog
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bede
3y ago
Thanks for the recommendation
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by
bede
3y ago
Thanks!
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by
bede
3y ago
Not absolute, but pausing a sub with an explanation sends an immediate message. Which services would you recommend? I'm mostly after a broad and fresh electronic music catalogue.
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bede
3y ago
Depth and breadth of electronic music catalogue and switching cost. Former is probably narrowing rapidly. What would you recommend? Building Apple's future streaming monopoly isn't particularly appealing. Small perhaps, but pausin
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bede
3y ago
As a scientist working in public health, this decision burned my faith in Spotify. They were taking down conspiracy theory podcasts daily while bankrolling Rogan to provide a platform with insane reach for cranks like Robert Malone. I cance
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by
bede
3y ago
Title should be suffixed with (2005)
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