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bedast
searching Neon…
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bedast
3y ago
As noted in the article, it bans the app from the app stores, not individual devices. It doesn't penalize individuals for having and using the app.
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bedast
3y ago
I have my own domain attached to icloud mail at the moment. But primarily, I have my own domain and can move it to wherever I need it. Icloud mail isn't the best thing in the world, still, but it's more cost efficient than trying
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bedast
3y ago
I'm frequently reminding people that Google is not an email provider nor a search engine nor really anything else it pretends to be, but that it's a data harvesting and ad company. Thankfully I've been becoming less reliant o
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bedast
3y ago
Sometimes it's not just about getting rid of an annoyance. I've stuck to my guns with ad blocking to protect myself from malicious ad content. In terms of content creators getting paid, I pay for a Youtube Premium subscription to
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bedast
3y ago
Reading the article, I failed to see what link they found. The headline here matches the one on the article so I'm not calling that into question, but what seems to be more accurate is "Mobile phone calls correlated with increased
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bedast
3y ago
In my experience, the White Ambiance lights don't get as dim as the other Hue bulbs. In places where I wanted even lower light, I've had to use their White Ambiance Filament or Color Ambiance bulbs.
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bedast
3y ago
I've noticed the White Ambiance lights don't dim to a very low level for night time night light type of use, but the White and Color Ambiance bulbs can get far dimmer. Also the White Ambiance Filament bulbs seem to get dimmer than
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bedast
3y ago
I have a box of batteries I need to dispose of that I haven't just tossed in the garbage. My local Home Depot used to take batteries, but only non-lithium ion batteries. And sometime last year they stopped accepting any batteries. I st
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bedast
3y ago
I feel like there's not enough easily accessible information in the wild about what you're supposed to do with old electronics, and especially batteries. You're not supposed to throw any type of battery in the trash, let alon
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bedast
4y ago
The article notes that, yes, he will remain as spokesperson.
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bedast
4y ago
You might get a good few years from the drug. You have to still do the work to make the changes permanent.
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bedast
4y ago
In my experience, if you're going to use GLP-1 RA for weight loss, it needs to be part of a larger program of changes, including lifestyle changes. That you have to lead the charge on. The people that say losing weight on these means y
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bedast
4y ago
Mounjaro will never be approved for obesity. The documentation for dosing is for diabetes. If the trend follows with how Novo Nordisk has released their versions of this, dosing for weight loss will be different than dosing for diabetes car
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bedast
4y ago
This is not only an American issue. I've seen people in the UK struggle to get access to treatments and devices through the NHS. Canada tends to follow what the US is doing even though they have their more socialized system. It all ten
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bedast
4y ago
Do you even know what A1c is? Or how GLP-1 RA achieves this goal? GLP-1 RA does NOT achieve a reduced A1c through weight loss. It achieves improved glycemic control by slowing the release of glucose into the blood as well as promoting incre
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bedast
4y ago
Tirzepatide is in testing. The weight loss variant will not be called Mounjaro. If they follow similar patterns from Novo Nordisk with Saxenda and Wegovy, dosing will be different for the weight loss variant, which means it won't carry
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bedast
4y ago
You are among the people just learning about this class of drug. It's been around since 2004 (Byetta). I've been taking it since 2012 (Victoza). Even then, it was known to promote weight loss (Saxenda approved around 2014). This i
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bedast
4y ago
Significantly increasing production for a temporary benefit is going to require significant investment. Since it is a temporary benefit, it's probably not worth that significant investment. Because eventually the demand will falter. An
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bedast
4y ago
They also probably don't want to put significant investment in boosting production knowing that will be temporary since the weight loss effects aren't permanent. As someone who has been on GLP-1 RA for a decade, starting with Vict
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bedast
4y ago
Brand new drugs tend to take a while to get on insurance formularies. I believe Mounjaro is still missing in most formularies. Lilly wants people on their drug, not the competition.
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bedast
4y ago
Allowing the coupon to be used for the treatment of obesity is an implicit approval for the drug to be used in this way, and coupons are a form of marketing. Lilly cannot approve nor market this drug in a way that is off-label. This is why
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bedast
4y ago
> That it is currently labeled only for Type 2 diabetes is a marketing decision by the manufacturer, not a characteristic of the drug. Regulatory approval. It is a diabetes drug because it has been evaluated as such, including understand
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bedast
4y ago
I care that many people I know are losing glycemic control because they're going on a waiting list for their medication while Kim K and Elon Musk and TikTok promote easy mode cosmetic weight loss.
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bedast
4y ago
And dose. The doses are different. You need a much higher dose than is typically prescribed for diabetes to get the full weight loss benefits. Part of getting approval for on-label use of these drugs is understanding this part of it.
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bedast
4y ago
Yes, this is what Novo Nordisk did with Victoza around 2014 with the release of Saxenda. And then again with Ozempic around 2021 with Wegovy. These weight loss versions exist. And there will be one likely this year based on tirzepatide from
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bedast
4y ago
It's weird for anyone to "feel abandoned by Big Pharma" when you abused a coupon to get a drug for off-label use, and terms were changed to match its on-label use. Especially when there's versions of these drugs with on-
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bedast
4y ago
Yeah, feel free to spend the $1200/mo for it then. Because that's off-label use when there are drugs in this class with on-label weight loss use. And sometime this year, tirzepatide is expected to be among them. The coupon was cha
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bedast
4y ago
The biggest problem using these drugs for weight loss is they need to be used as part of a program that also includes making lifestyle changes. If you don't push the changes and just do things to your limits, when you stop the drug, yo
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bedast
4y ago
If she has insurance and a diabetes diagnosis, the coupon should apply. The coupon is still there. I use it.
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bedast
4y ago
Mounjaro is not an obesity drug. It's a type 2 diabetes drug. Do not call it an obesity drug. The headline is editorialized. The linked article's headline: The ‘next Ozempic’ became a social media sensation. Then everything change
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