armadsen

6 ms·

1.
by armadsen 2mo ago
That is true, but it's mostly true of people sending using a straight key (basically a simple button) or a bug (semi-automated key). Most morse code operators these days use a keyer paddle, and a fair number use a computer to send mors
2.
by armadsen 3mo ago
My father in law passed away from it about a year and a half ago at age 64. Two of his kids have tested positive for the mutation. They don’t have symptoms yet (they’re in their 20s and 30s).
3.
by armadsen 3mo ago
It’s sometimes frustrating to try to explain that the gene mutation in the family (PSEN1 in our case) means it’s a 100% chance you get it. Most people have never heard of it, so you get a lot of “well, maybe you’ll be lucky and it won’t aff
4.
by armadsen 3mo ago
There are multiple specific possible mutations that cause 100% penetrant dominantly inherited early onset Alzheimer’s. And there are three genes where mutations can cause it: PSEN1, PSEN2, and APP. The average age of onset seems to depend o
5.
by armadsen 3mo ago
My wife’s family has PSEN1-mutation EAD (my wife didn’t inherit it). In that particular case it does seem that the mutated genes relate directly to Amyloid production and clearing, and there are ongoing clinical trials for the use of the ne
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by armadsen 4mo ago
It's a figure of speech.
7.
by armadsen 5mo ago
That is indeed part of the charm. The people who like swing lens panoramic cameras like the Widelux like that look. The alternative is something like the Hasselblad Xpan, or even just a panoramic crop from a regular camera. A swing lens doe
8.
by armadsen 5mo ago
Right. The whole revival was his idea, according to the story told by the other founders. Also, presumably he has funded the whole effort so far.
9.
by armadsen 5mo ago
Yeah, I've been waiting for it for years too. I thought it was going to be substantially more than $4400 (more like $6-7K). Under $1,000 is unfortunately simply impossible. Used Wideluxes go for a fair bit more than $1K. That said, too
10.
New mechanical panoramic film camera from Jeff Bridges(wideluxx.com)
224 points by armadsen 5mo ago|110 comments
11.
by armadsen 5mo ago
Eddie Rocket's is an Irish chain of American diners. I've eaten there in Dublin. Although at least that location is downtown, and in a bigger building, not a classic diner style building. The inside is very much American Diner th
12.
by armadsen 5mo ago
Many of the film cameras that people 3D print essentially outsource that stuff to off-the-shelf focusing helicoids which are readily available, along with medium or large format lenses which are traditionally mounted in a leaf shutter anywa
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by armadsen 6mo ago
The animation was visible on Safari when I viewed it very early this morning (10 hours ago), and again about 3 hours ago.
14.
by armadsen 6mo ago
Yeah, it’s really starting to depress me how much text published to the web is written using an LLM now. Things that seem interesting at first glance become much less appealing when they have that telltale LLM quality to them, and I also st
15.
by armadsen 7mo ago
Spina Bifida is not primarily a genetic disease. It's caused by a failure of the neural tube in the developing embryo to close fully. No one knows the exact causes, but folic acid deficiency in the mother before and during pregnancy ma
16.
by armadsen 7mo ago
Thanks for sharing about your daughter. It's good to hear from other parents dealing with it. My daughter with spina bifida is only 18 months. It's early of course, but so far she's right on track cognitively and socially. I
17.
by armadsen 7mo ago
The main goal of physical repair of the defect in utero is actually to reduce the incidence of hydrocephalus and hindbrain herniation, which are very common in people with Spina Bifida. The existing fetal surgery reduces the incidence of hy
18.
by armadsen 7mo ago
Not only is it possible, fetal surgery is more or less standard treatment for spina bifida at this point. The news here is about the stem cell patch being applied during the surgery. (I have a child with spina bifida. We tried to get her in
19.
by armadsen 7mo ago
Seriously. My son and I are about 3/4ths through Fellowship of the Ring after he loved The Hobbit. We’ve read all of Narnia, Wildwood, and many other (long!) books and book series together. Either his mom or I have read to him very nea
20.
by armadsen 7mo ago
No. https://www.etymonline.com/word/chintzy
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by armadsen 7mo ago
To be a little more precise, f is not a camera-specific constant. It's the focal length of the lens. It's a formula that tells you the diameter of the entrance pupil. So at a focal length of 50mm, an aperture value of f/2 mea
22.
by armadsen 7mo ago
My experience with my Prius PHEV is the same. I don’t even have a level 2 charger. I just plug it in in the garage overnight, and most days I don’t use any gas. The only time the ICE turns on before my EV range is up is if I hit the windshi
23.
by armadsen 7mo ago
Yeah, I didn’t realize we were calling hybrids “EV”s now. Also, the BYDs I’ve been in were chintzy garbage as far as fit and finish goes. Can’t speak to their reliability, or other aspects of them, though.
24.
by armadsen 8mo ago
For what it’s worth, Philo Farnsworth and John Logie Baird were friendly with each other. I was lucky to know Philo’s wife Pem very well in the last part of her life, and she spoke highly of Baird as a person. David Sarnoff and RCA was an e
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by armadsen 9mo ago
My understanding is that amyloid plaques can actually be seen with a specialized PET scan now, so it can be more definitively diagnosed in living people.
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by armadsen 9mo ago
Biology is another discipline where the author is wrong. See e.g.: https://en.wikipedia.org/wiki/Sonic_hedgehog_protein
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by armadsen 10mo ago
I was lucky to work with him for a while. He’s a great guy IRL too.
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by armadsen 11mo ago
The rainy season is during the summer (Northern Hemisphere's winter). Outside of those months it doesn't rain very often! I've spent two winters (June-August) in Namibia and can't recall much, if any rain. But now that w
29.
by armadsen 1y ago
Yep. My new car has a digital rear view mirror. You flip a switch and the rear view mirror becomes a screen showing a feed from a camera on the back of the car. It’s nice for night time as well as when the rear window is blocked by rear sea
30.
by armadsen 1y ago
I’ve spent significant time in Africa. South Africa is higher than the US despite being a place where everyone has razor wire topped walls around their houses, and having the 5th highest murder rate in the world. The US has problems. I myse

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