ampdepolymerase

6 ms·

1.
by ampdepolymerase 2mo ago
Can you add support for touch?
2.
by ampdepolymerase 1y ago
The phospholipid micelles are non-trivial (trade secret) to make and it's the major reason why African nations and other countries have not been able to successfully create mRNA vaccines at scale. A cell is a bundle of proteins wrapped
3.
by ampdepolymerase 2y ago
> getting infected with the zika virus (probably the best thing to do IMO Virology based methods don't last very long because the immune system adapts quickly. If you want to go down that route, make sure you have experts on hand.
4.
by ampdepolymerase 2y ago
You should try to convince the others on the Facebook groups to undergo full genome DNA sequencing (around $1K USD, usually not covered by insurance, I would pay for the other patients if I were you, their data is more than worth it given i
5.
by ampdepolymerase 2y ago
> the mitochondria is the powerhouse of the cell The explanation doesn't get much better at higher levels. You have the Krebs cycle which biology people religiously memorize but it doesn't really explain much either. The actu
6.
by ampdepolymerase 2y ago
Also "off target effects".
7.
by ampdepolymerase 2y ago
Work/volunteer as a minimum wage software developer lab rat (or whatever your day job speciality is). There are plenty of labs that are in need of free labor when it comes to software/engineering support in general, just ask aroun
8.
by ampdepolymerase 2y ago
Most of the pop sci books are useless for practical use cases, and similarly the Feynman lectures self select for the physics/mathematically inclined. Biology is a leaky abstraction, it's very hard to do anything with rigor withou
9.
by ampdepolymerase 3y ago
No, no, no. Explanation is inaccurate. The central dogma is the central dogma because information flow is primarily one way (yes there are exceptions i.e. epigenetics but primary information flow is from DNA to protein) and this is the fu
10.
by ampdepolymerase 4y ago
> This is still relevant to his concern, but from the other end. They might be making the labor artificially scarce to increase pay. This is very much true. I find that a lot of people in tech seem to put healthcare on a pedestal and b
11.
by ampdepolymerase 4y ago
Note FDA rules require them to retain the data for a few years.
12.
by ampdepolymerase 4y ago
There is a bigger iceberg lurking around. Look up the people who control medical school accreditation and funding. They have more blood on hands than many other industries put together. Medical innovation has been slowed down by magnitudes
13.
by ampdepolymerase 4y ago
More specifically pseudo science not guided by empiricism. The line between science and pseudo science is very thin. Scientific theories are often incorrect, especially in life science, but we refine upon them based in empirical and observe
14.
by ampdepolymerase 4y ago
Voit looks gimmicky. Uri Alon's treatment (An Introduction to Systems Biology) is much better.
15.
by ampdepolymerase 4y ago
There is a bottleneck in the number of MD positions. Without the MD title, your typical life science researcher cannot easily carry out medical research. Medical education and training has a scale problem.
16.
by ampdepolymerase 5y ago
I won't put too much stock in unglazed clay cooking ware.
17.
by ampdepolymerase 5y ago
The best C and C++ package manager I have used is Xmake/Xrepo. They support all the major package repositories out of the box including Vcpkg and Conan. https://github.com/xmake-io/xmake#supported-package-reposito.
18.
by ampdepolymerase 5y ago
Human trials for drugs is the expensive part. If the situation is urgent, look into compassionate use and right to try. If you have time, the fastest way to get it to production is to have the trials done in a lower cost country. At the end
19.
by ampdepolymerase 5y ago
I haven't looked into the Moderna vaccine but in general there are many ways to get rid of a virus. Using the typical B cell + viral glycoprotein is the most obvious way as viral activity is hard to detect when replicating inside a cel
20.
by ampdepolymerase 5y ago
Fwiw, rarely can lab designed viruses i.e. made through splicing have features that are more "optimal" (or efficient) than those that are evolved. Directed evolution is truly marvelous when done properly (it won a Nobel!).
21.
by ampdepolymerase 5y ago
Just because the bacteria is dead doesn't mean the toxins it produced have been decomposed by the heat. Leaving food out is very bad idea.
22.
by ampdepolymerase 5y ago
The math sounds nonsensical. The risk adjusted exposure from a reactor should definitely be higher as you would be closer to the threshold of DNA bond breaking. Being stabbed once a year isn't necessary better than getting hundred pape
23.
by ampdepolymerase 5y ago
You don't, not without either resequencing it with another sequencing system or benchmarking the sequencer with a known sequence.
24.
by ampdepolymerase 5y ago
GC rich regions as in hairpin loops? How would the sequencer deal with those?
25.
by ampdepolymerase 5y ago
I recommend reading this review https://genomebiology.biomedcentral.com/articles/10.1186/s13... I guess there are limits to ensemble methods if the underlying accuracy doesn't increase. I don't work on g
26.
by ampdepolymerase 5y ago
The one I linked to is a decade out of date and OEM discontinued.
27.
by ampdepolymerase 5y ago
A used laboratory grade NGS system can be had for less than 10K https://www.ebay.com/itm/265148387179 Nanopore is still not quite ready yet for precise and high accuracy sequencing. Give it another five years.
28.
by ampdepolymerase 5y ago
This is not the first attempt. Growing tiny brain organoids is fairly well understood, scaling it up is not. I have not read the paper but previous attempts at this have struggled with getting useful outputs out of the neural culture, most
29.
by ampdepolymerase 5y ago
Same quality yes, but not access to the same opportunities.
30.
by ampdepolymerase 5y ago
Tertiary education at the elite level is rarely about the quality of education. The difference between Georgia Tech and Columbia or Harvard's CS program is not that stark. However, the story is completely different when it comes to alu

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