DrAwdeOccarim

6 ms·

1.
by DrAwdeOccarim 3mo ago
The state of "Scientific AI". I know LLMs are accelerating at doing computer work, and I've experienced the acceleration of using LLMs to do science, but it's more along the lines of debugging and stitching together pipe
2.
by DrAwdeOccarim 4mo ago
Yes! I had a mandibular advancement device for many years, but after about 10, my lower jaw stopped resetting all the way in the morning. I forced myself to find the right CPAP (nasal pillows with fabric elastic chin strap to keep my mouth
3.
by DrAwdeOccarim 6mo ago
Totally doing this today! Have you tried OpenJarvis or NemoClaw (is it out yet?). I want to use my computer “through” the LLM.
4.
by DrAwdeOccarim 6mo ago
I want this, but using Nemotron Super 3 running local (128gb M5 Max macbook pro) that I use the computer “through”. Does Goose AI aspire/do this? I just started working on this yesterday.
5.
by DrAwdeOccarim 7mo ago
QSL! Boston, MA
6.
by DrAwdeOccarim 8mo ago
OK, I'll look around. Thanks!
7.
Ask HN: Local models to support home network infrastructure?
6 points by DrAwdeOccarim 8mo ago|3 comments
8.
by DrAwdeOccarim 8mo ago
https://thepihut.com/products/highpi-raspberry-pi-b-plus2-ca...
9.
by DrAwdeOccarim 8mo ago
I love this! I really wanted to go down this road when my kids were younger, but the paucity of floppys and the low storage space made me go down the Avery business card print outs with RFID stickers on the back and a raspberry pi with an R
10.
by DrAwdeOccarim 9mo ago
I use Opus 4.5 and GPT 5.2-Codex through VS Code all day long, and the closest I've come is Devstral-Small-2-24B-Instruct-2512 inferring on a DGX Spark hosting with vLLM as an "Open AI Compatible" API endpoint I use to power
11.
by DrAwdeOccarim 10mo ago
Does anyone know how this actually was done? Like, did they export every frame as a PNG and then run them each one by one through the model? Or did they somehow "load" the video into the model directly (which then internally someh
12.
by DrAwdeOccarim 11mo ago
Do yourself a favor and study for both your technician and general at the same time (I’m assuming you live in the US). HF is exponentially more fun than just VHF/UHF.
13.
by DrAwdeOccarim 1y ago
I’m surprised by your strong wording. >”… severe side-effects and likely consequences of long-term statin use, even low doses.” Could you provide a few reputable clinical outcomes studies to support your statements? I was unaware of thes
14.
by DrAwdeOccarim 1y ago
I don’t disagree with your point, but I just would like to point out that there are over 100 known post-transcriptional modified RNA bases [1]. In fact, tRNA are more modified bases than canonical if taken as a whole. AND! the ribosome can’
15.
by DrAwdeOccarim 1y ago
LM Studio lets you run a model as a local API (OpenAI-compatible REST server).
16.
by DrAwdeOccarim 1y ago
Yes, I use LM Studio daily with Qwen 3 30b a3b. I can't believe how good it is locally.
17.
by DrAwdeOccarim 1y ago
Yes. LM Studio acts like an OAi endpoint when you turn the server on.
18.
by DrAwdeOccarim 1y ago
LM Studio. I just vibe code the nodeJS code.
19.
by DrAwdeOccarim 1y ago
I adore Qwen 3 30b a3b 2507. Pretty easy to write an MCP to let us search the web with Brave API key. I run it on my Macbook Pro M3 Pro 36 GB.
20.
by DrAwdeOccarim 1y ago
Minstral small 3.2 Q4_K_M and Gemma 3 12b 4 bit are amazing. I run both in LM Studio on a Macbook Pro M3 Pro with 36GB of RAM.
21.
by DrAwdeOccarim 1y ago
The author says 36GB unified ram in the article. I run the same memory M3 Pro and LM Studio daily with various models up to the 30b parameter one listed and it flies. Can’t differentiate between my OAi chats vs locals aside from modern cont
22.
by DrAwdeOccarim 1y ago
I’m not sure that’s super feasible any longer with the advent of cheap SDRs. Over-the-horizon HF broadcast can be heard with a simple speaker wire antenna inside your house. If anyone is interested in trying to deploy such an idea, I’d love
23.
by DrAwdeOccarim 1y ago
I've been building MCP servers so I can grant local LM Studio LLMs access to the internet and to my local files. The way I've been thinking about MCP has been how you unshackle the local models as I believe the future will be infe
24.
by DrAwdeOccarim 1y ago
Yea, I’ve seen cashing out the principal+next investment and letting the rest ride.
25.
by DrAwdeOccarim 1y ago
Ah yea, biotech has been around for a while now and almost all best selling drugs are biotech drugs now a days.
26.
by DrAwdeOccarim 1y ago
Unsure if you’re genuine or trying to be edgy, but I’ll bite—-yes, most of them make significant profits currently.
27.
by DrAwdeOccarim 1y ago
Not op, but I’m in the field and can give you some things to read about: - CAR-T - CRISPR - PRIME editing - Base editing - Modified mRNA - PD-1 inhibitors - On the cusp of personalized cancer vaccines - ADCs - Structure correctors - Targete
28.
by DrAwdeOccarim 1y ago
This is a perfect analogy. Source: Am structural biochemist
29.
by DrAwdeOccarim 1y ago
And Brownian motion all but guaranteeing everything bumps into everything else constantly!
30.
by DrAwdeOccarim 1y ago
did it work?

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