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Bikanta
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A Nano Step for Man, a Giant Leap for Mankind
(techcrunch.com)
1 points
by
Bikanta
11y ago
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0 comments
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by
Bikanta
12y ago
It's an emission light source or probe that can be directed to specific cells with targeting agents. On our website (www.bikanta.com) you can find links to some of our publications and if you would like more literature and information
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by
Bikanta
12y ago
We are planning to pursue the SBIR grant route, but there is a lag time in the grant application process and we are eager to supplement our current developmental traction in the meantime with funds from other sources as well.
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by
Bikanta
12y ago
I'm happy to answer these technical questions. It's nice to share that info as that is what makes them so valuable. The fluorescence comes from nitrogen-vacancy centers. Here is a link showing the excitation and emissions spect
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by
Bikanta
12y ago
:-) Thanks for that share!
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by
Bikanta
12y ago
I'm glad you asked! I would encourage you to look at this article where YC recently announced how it will be backing bitechs: http://www.nature.com/news/start-up-investor-bets-on-biotech... . We are excited to s
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by
Bikanta
12y ago
The in vivo pathologies and applications we are targeting initially are primarily nearer to the surface (i.e metastatic node detection, skin pathologies) or procedures where surgeons can use NIR fluorescence imaging systems that simultaneou
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by
Bikanta
12y ago
Toxicity concerns are always utmost to consider when developing tools for the clinic! Thus far, all studies regarding nanodiamonds have shown biocompatibility and non-toxicity. Coming from a research background and having done a number of
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by
Bikanta
12y ago
Thanks for the props! We plan to offer a few different sizes of the brightest diamonds possible to our customers. The sizing and separation of the nanodiamonds can be accomplished a few different ways, the challenge is always in preventing
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by
Bikanta
12y ago
these probes can be visualized by standard fluorescence imaing instruments including fluorescence microscopes, TIRF, gel scanners, flow cytometry, optical animal scanners, clinical cameras etc. They also have long fluorescence lifetimes an
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by
Bikanta
12y ago
you are correct, this is primarily targeted to disease states with ligands such as antibodies, aptamers, fab fragments, etc.
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by
Bikanta
12y ago
that is actually one area of applications we are exploring! I'd love to have a chat with you about it.
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by
Bikanta
12y ago
These nanodiamonds are cheaper to synthesize than what you find current optical imaging agents on the market for.
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by
Bikanta
12y ago
both, also for areas such as single molecule imaging
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by
Bikanta
12y ago
You are correct in the fact that the kidney's are one route of clearance for small agents that are injected. However, these are typically small molecule agents or particles on the lower size range at a couple nms in diameter. To refe
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by
Bikanta
12y ago
Hi everyone! I'm Ambika, one of the founders of Bikanta and inventors of this technology. I'd love to answer any questions that you may have. Here is also a link to our website: www.bikanta.com Thanks for the share from PG'