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Personalized mRNA vaccines are in fact, extremely new, and only made possible by recent advances across multiple fields. This comment reveals a total lack of ba
by HedonicEscal8r 28d ago
Personalized mRNA vaccines are in fact, extremely new, and only made possible by recent advances across multiple fields. This comment reveals a total lack of basic understanding on this topic.
- cogman10 28d agoI believe the comment was talking specifically about immunotherapy rather than personalized mRNA. But I'd agree it's still misinformed as immunotherapy has been a game changer across multiple cancers.
- HedonicEscal8r 28d agou/danjl was originally asking about "this class of drugs", which is more reasonably interpreted as referring to personalized mRNA vaccines rather than the much broader concept of (personalized or not) immunotherapy. The comment is wrong because it's stupid. Just because we've known that personalized immunotherapy was a promising idea for a long time, and have been trying it with the limited tools we had (CAR T being the poster child, and while an incredible advancement for blood cancers and many other diseases, it is notoriously dangerous and expensive), does not mean we had the technology to accomplish it. Today's results are only possible because of recent advancements in multiple fields, and to respond with "they've tried immunotherapy for decades" is profoundly ignorant. You may as well say, "scientists have been trying to cure cancer for years."
- ChickeNES 28d ago> This comment reveals a total lack of basic understanding on this topic. My thoughts as well, Keytruda alone has been a miracle to many many people at this point (quoting GP: "scientists, for decades, have tired [sic] to harness the immune system to attack cancer and it almost never works."), I frequently get ads for local CAR-T centers (unthinkable a little over a decade ago)