6 ms·

8 people as the entire control group... yeah I'd say "may" is the operative word in the title. My takeaway from long covid is that it's probably as severe as th

8 people as the entire control group... yeah I'd say "may" is the operative word in the title. My takeaway from long covid is that it's probably as severe as the much more deadly pandemic of the Spanish Flu. Considering there's now a newfound interest in "long flu", I think a spotlight has now been placed on the impact of severe respiratory illness. Whether that illness be covid or one of the any other respiratory illnesses.

jambalaya8 2mo ago
Yeah, twelve patients and eight in the control group isn't really a study.
- thenerdhead 2mo ago
  is a small proof of concept study not a study anymore? gastric biopsies aren’t exactly easy to obtain at scale.
  - Fomite 2mo ago
    They are studies, and frankly, without something like this, doing things like the appropriate power calculations and risk assessments for larger studies would be hard to do.
    - jambalaya8 2mo ago
      I would consider things like these the equivalent of a test to see if a study is viable, not a study. Sort of like, okay, if I have a hundred water balloons and I dropped fifty of those water balloons off the top of my house growing up, and fifty off the top of the Empire State building, would the latter always be that much worse? Just a few off the first and I can guess the outcome, and let's call that a control group, but the second, who knows... sure you might get lucky and knock one or two people out (or get a couple of good people showing results or seeming connections you want in a study) but you probably need more than a few to prove it isn't just a fluke. ;) Okay, messing around with the water balloons. Not with the study thing.
jMyles 2mo ago
[flagged]
- Izkata 2mo ago
  Yeah, it's a rebranding of what we used to call "post-viral fatigue" or "post-viral syndrome", except specific to this one virus.
  - PaulKeeble 2mo ago
    Post viral fatigue has a limited time frame, you recover from it. Long Covid is a lot more like ME/CFS, looks similar to PVF early on but you don't recover from it and the symptoms often progress and get worse and some people die from it. Its a lifelong severely disabling condition.
  - jMyles 2mo ago
    Is the term "long covid" specific to COVID-19 though (in other words, excluding oc43, hku1, 299e, and nl61)? Or does it mean "long coronavirus disease", including all covids? I see it being used both ways.
    - Izkata 2mo ago
      I don't know if it's drifted, but it was created in late 2020/2021 specifically for COVID-19.
      - jMyles 2mo ago
        Surely it's strange to use the term "long covid" to describe the effects of only one covid, when at least four others have been circulating for decades or more and have been causing similar effects?
- deleted 2mo ago
  [deleted]
- Erem 2mo ago
  I’m here to disagree with what you said about lockdowns. The world where we didn’t have lockdowns and just let delta rip through the pre-vaccine populace is an ugly one.
thenerdhead 2mo ago
severity is only one factor in developing long covid. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00684-9/fulltext https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
naturalmovement 2mo ago
Funny that reactive arthritis has been around for decades but no one dares call it "long chlamydia" I guess it doesn't sell YouTube clicks as well.
- dmix 2mo ago
  Usually they add “chronic” like chronic Lyme disease https://en.wikipedia.org/wiki/Chronic_Lyme_disease https://en.wikipedia.org/wiki/Chronic_Lyme_disease
- fsckboy 2mo ago
  wikipedia: Reactive arthritis, previously known as Reiter's syndrome,[1] is a form of inflammatory arthritis[2] that develops in response to an infection in another part of the body (cross-reactivity). Coming into contact with bacteria and developing an infection can trigger the disease.[3] By the time a person presents with symptoms, the "trigger" infection has often been cured or is in remission in chronic cases, thus making determination of the initial cause difficult. The most common triggers are intestinal infections (with Salmonella, Shigella or Campylobacter) and sexually transmitted infections (with Chlamydia trachomatis);[8] however, it also can happen after group A streptococcal infections.[9][10]
- deleted 2mo ago
  [deleted]

jambalaya8 2mo ago

Yeah, twelve patients and eight in the control group isn't really a study.

thenerdhead 2mo ago
is a small proof of concept study not a study anymore? gastric biopsies aren’t exactly easy to obtain at scale.
- Fomite 2mo ago
  They are studies, and frankly, without something like this, doing things like the appropriate power calculations and risk assessments for larger studies would be hard to do.
  - jambalaya8 2mo ago
    I would consider things like these the equivalent of a test to see if a study is viable, not a study. Sort of like, okay, if I have a hundred water balloons and I dropped fifty of those water balloons off the top of my house growing up, and fifty off the top of the Empire State building, would the latter always be that much worse? Just a few off the first and I can guess the outcome, and let's call that a control group, but the second, who knows... sure you might get lucky and knock one or two people out (or get a couple of good people showing results or seeming connections you want in a study) but you probably need more than a few to prove it isn't just a fluke. ;) Okay, messing around with the water balloons. Not with the study thing.

jMyles 2mo ago

[flagged]

Izkata 2mo ago
Yeah, it's a rebranding of what we used to call "post-viral fatigue" or "post-viral syndrome", except specific to this one virus.
- PaulKeeble 2mo ago
  Post viral fatigue has a limited time frame, you recover from it. Long Covid is a lot more like ME/CFS, looks similar to PVF early on but you don't recover from it and the symptoms often progress and get worse and some people die from it. Its a lifelong severely disabling condition.
- jMyles 2mo ago
  Is the term "long covid" specific to COVID-19 though (in other words, excluding oc43, hku1, 299e, and nl61)? Or does it mean "long coronavirus disease", including all covids? I see it being used both ways.
  - Izkata 2mo ago
    I don't know if it's drifted, but it was created in late 2020/2021 specifically for COVID-19.
    - jMyles 2mo ago
      Surely it's strange to use the term "long covid" to describe the effects of only one covid, when at least four others have been circulating for decades or more and have been causing similar effects?
deleted 2mo ago
[deleted]
Erem 2mo ago
I’m here to disagree with what you said about lockdowns. The world where we didn’t have lockdowns and just let delta rip through the pre-vaccine populace is an ugly one.

thenerdhead 2mo ago

severity is only one factor in developing long covid. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00684-9/fulltext https://www.thelancet.com/journals/laninf/article/PIIS1473-3...

naturalmovement 2mo ago

Funny that reactive arthritis has been around for decades but no one dares call it "long chlamydia" I guess it doesn't sell YouTube clicks as well.

dmix 2mo ago
Usually they add “chronic” like chronic Lyme disease https://en.wikipedia.org/wiki/Chronic_Lyme_disease https://en.wikipedia.org/wiki/Chronic_Lyme_disease
fsckboy 2mo ago
wikipedia: Reactive arthritis, previously known as Reiter's syndrome,[1] is a form of inflammatory arthritis[2] that develops in response to an infection in another part of the body (cross-reactivity). Coming into contact with bacteria and developing an infection can trigger the disease.[3] By the time a person presents with symptoms, the "trigger" infection has often been cured or is in remission in chronic cases, thus making determination of the initial cause difficult. The most common triggers are intestinal infections (with Salmonella, Shigella or Campylobacter) and sexually transmitted infections (with Chlamydia trachomatis);[8] however, it also can happen after group A streptococcal infections.[9][10]
deleted 2mo ago
[deleted]