7 ms·

> I highly doubt there'll ever be research in this area, but I'm very curious about whether it'll ever be possible to induce schizophrenia for a time, similar t

> I highly doubt there'll ever be research in this area, but I'm very curious about whether it'll ever be possible to induce schizophrenia for a time, similar to how psychedelics or dissociatives can induce altered mind states. It is not possible, by definition; here’s a portion of the DSM 5 definition of schizophrenia: “ The disturbance is not attributable to the physiological effects of a substance (e.g., a drug of abuse, a medication) or another medical condition” Hard to find a publicly accessible DSM link, but here is an excerpt https://floridabhcenter.org/wp-content/uploads/2021/03/Pages-2019-Psychotherapeutic-Medication-Guidelines-for-Adults_Schizophrenia_06-04-20.pdf https://floridabhcenter.org/wp-content/uploads/2021/03/Pages...

jvanderbot 1y ago
This is true, but I wonder if GP spoke naively about inducing symptoms that are similar enough that we can learn about what triggers those symptoms in otherwise healthy individuals. Kind of like how we were "lucky" to get a guy with a railroad spike through his brain to learn about how brain damage affects personality and impulsiveness..
- LoganDark 1y ago
  oh it was definitely for selfish reasons, I just want to feel it for myself. But I do have a feeling that it would advance science as well, that'd be a cool bonus I guess.
epsilonic 1y ago
This attribution criteria might be subject to revision based on research like this: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2829840 https://jamanetwork.com/journals/jamanetworkopen/fullarticle...
LoganDark 1y ago
> It is not possible, by definition I use schizophrenia to refer to the experience, not to the diagnosis. I'm not sure what to call the experience of schizophrenia other than schizophrenia, given it's not synonymous with psychosis. (Though, granted, I would also want to try psychosis someday; even if it's a terrible experience and I never want to do it again, I want to truly know what it's like. Hopefully without permanent brain damage though. That stipulation heavily limits my options.)

jvanderbot 1y ago

This is true, but I wonder if GP spoke naively about inducing symptoms that are similar enough that we can learn about what triggers those symptoms in otherwise healthy individuals. Kind of like how we were "lucky" to get a guy with a railroad spike through his brain to learn about how brain damage affects personality and impulsiveness..

LoganDark 1y ago
oh it was definitely for selfish reasons, I just want to feel it for myself. But I do have a feeling that it would advance science as well, that'd be a cool bonus I guess.

epsilonic 1y ago

This attribution criteria might be subject to revision based on research like this: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2829840 https://jamanetwork.com/journals/jamanetworkopen/fullarticle...

LoganDark 1y ago

> It is not possible, by definition I use schizophrenia to refer to the experience, not to the diagnosis. I'm not sure what to call the experience of schizophrenia other than schizophrenia, given it's not synonymous with psychosis. (Though, granted, I would also want to try psychosis someday; even if it's a terrible experience and I never want to do it again, I want to truly know what it's like. Hopefully without permanent brain damage though. That stipulation heavily limits my options.)